简介:Thecomplexnatureoflaser-materialinteractioncausesnon-stoichiometricablationofalloysamples.Thisisattributedtomatrixeffect,whichreducesanalyzingcapability.Toaddressthisissue,theanalyticalperformanceofthreedifferentnormalizationmethods,namelynormalizationwithbackground,internalnormalizationandthreepointsmoothingtechniquesatdifferentparametersettingsisstudiedforquantificationofAgandZnbyLaserinducedbreakdownspectroscopy(LIBS).TheLIBSspectraoffiveknownconcentrationofsilverzincbinarycompositeshavebeeninvestigatedatvariouslaserirradiances(LIs).CalibrationcurvesforbothAg(I)line(4d^105s^2S1/2→4d^105p^2P1/2at338.28nm)andZn(I)line(4s5s^3S1→4s4p^3P2at481.053nm)havebeendeterminedatLIof5.86×10^10Wcm^-2.SlopesofthesecalibrationcurvesprovidethevaluationofmatrixeffectintheAg–Zncomposites.Withcarefulsamplepreparationandnormalizationaftersmoothingatoptimumparametersetting(OPS),theminimizationofsamplematrixeffecthasbeensuccessfullyachieved.AgoodlinearityhasbeenobtainedinAgandZncalibrationcurveatOPSwhennormalizedthewholeareaofspectrumaftersmoothingandtheobtainedcoefficientsofdeterminationvalueswereR^2=0.995and0.998closerto1.Theresultsofmatrixeffecthavebeenfurtherverifiedbyanalysisofplasmaparameters.BothplasmaparametersshowednochangewithvaryingconcentrationatOPS.However,athighconcentrationofAg,theobservedsignificantchangesinbothplasmaparametersatcommonparametersettingPS-1andPS-2werethegestureofmatrixeffect.Inourcase,thebetteranalyticalresultswereobtainedatsmoothingfunctionwithoptimizedparametersettingthatindicatesitismoreefficientthannormalizationwithbackgroundandinternalnormalizationmethod.
简介:Variousagriculturalcropresiduesincludingcornstover,corncob,andsorghumstalkwithamoisturecontentof75wt%weresubjectedtoalongpretreatment(12-60h)withsupercriticalCO2(scCO2),atlowtemperature(50-80℃)andapressureof17.5-25.0Mpa.Thesugaryieldsfromtheenzymatichydrolysis(EH)ofthepretreatedsampleswereasmuchasthree-tofourfoldgreaterthanthoseaffordedbytherawmaterials.However,whenpretreatmentwasconductedwithinashorttime(e.g.0.5h),aspreviouslyreportedintheliterature,onlyaslightincreaseintheEHsugaryieldswasobserved.TheproposedscCO2pretreatmentmechanismdemonstratedtheroleofmoistureinthesystem.Wetting,softening,andswellingwereobservedtomainlyaffectthelignocellulosewhenasuitableamountofwaterwasadded.Finally,thesampleswereanalysedbyX-raydiffractionandscanningelectronmicroscopy,beforeandafterpretreatment,toinvestigatethechangesinthemicroscopicstructureofthebiomass.
简介:摘要目的分析该院2016-2017年3种抗癫痫药血药浓度监测数据。方法研究对象为抗癫痫药患者例数90例,均只使用一种抗癫痫药进行治疗,根据不同抗癫痫药方式对研究对象90例进行分组,患者收取时间在2016年1月2日到2017年1月2日,分为a组(丙戊酸钠药物)、b组(卡马西平药物),c组(苯妥英钠药物),对3种抗癫痫药血药浓度进行监测和分析。结果苯妥英钠、丙戊酸钠、卡马西平等抗癫痫药血药浓度结果具有显著差异,苯妥英钠偏离有效浓度范围比例较高,而丙戊酸钠在有效浓度范围内比例较高(P<0.05)。结论苯妥英钠、丙戊酸钠、卡马西平3种抗癫痫药血药浓度具有一定差异,丙戊酸钠在有效浓度范围内比例较高,同时正确进行药物监测,给予每位患者制定给药方式,能显著提高癫痫疾病治疗的有效性和安全性。
简介:EffectsoftheorientationandapexangleonthesettlingvelocityofconicalparticlesinBinghamplas-ticfluidsarenumericallyinvestigatedoveraReynoldsnumberrangeof1≤Re≤100,Binghamnumberrangeof0≤Bn≤100,andconeanglerangeof20≤α≤150°.Governingequations(ofcontinuityandmomentum)aresolvednumericallyusingthefiniteelementmethodtoobtainvelocityandpressurefieldsthatarepostprocessedtoobtainvaluesofthedragcoefficien.Futthermore,theeffectofconeori-entationontheflowfieldisvisualizedandexploredintermsofstreamlinecontoursandthemorphologyofyielded/unyieldedregions.Finally,theobtainedvaluesofdragarecorrelatedviaasimplepredictiveexpressionintermsofthemodifiedReynoldsnumber.Theeffectoftheconeangleondragisfoundtobemoderatebecausethedragforceactingonthelateralsurfaceisasmallfractionoftheoveralldrag.
简介:Glowdischargeisintroducedasanartificialdisturbancetoinvestigatetheevolutionoffirst-andsecond-modeinstabilitiesinahypersonicflatplateboundarylayer.ExperimentsareconductedinaMach6.5quietwindtunnelusingRayleighscatteringvisualizationandparticleimagevelocimetry(PIV).Detailedanalysisoftheexperimentalobservationsisprovided.Itisfoundthattheartificiallyintroduced17kHzdisturbance,whichbelongstothefirst-modefrequencyband,caneffectivelyenhancefirst-modewaves.Moreover,itcanenhancesecond-modewavesevenmoreintensely.Possiblemechanismstoexplainthisphenomenonarediscussed.
简介:Anovelgas-phaseelectrocatalyticcellcontainingalow-temperatureprotonexchangemembrane(PEM)wasdevelopedtoelectrochemicallyconvertCO2intoorganiccompounds.TwodifferentCu-basedcathodecatalysts(CuandCu-C)werepreparedbyphysicalvapordepositionmethod(sputtering)andsubsequentlyemployedforthegas-phaseelectroreductionofCO2atdifferenttemperatures(70-90℃).ThepreparedelectrodesCuandCu-CwerecharacterizedbyX-raydiffraction(XRD),X-rayphotoemissionspectroscopy(XPS)andscanningelectronmicroscopy(SEM).Asrevealed,CuispartiallyoxidizedonthesurfaceofthesamplesandtheCuandCu-Ccathodiccatalystswerecomprisedofaporous,continuous,andhomogeneousfilmwithnanocrystallineCuwithagrainsizeof16and8nm,respectively.Theinfluenceoftheappliedcurrentandtemperatureontheelectro-catalyticactivityandselectivityofthesematerialswasinvestigated.Amongthetwoinvestigatedelectrodes,thepureCucatalystfilmshowedthehighestCO2specificelectrocatalyticreductionratesandhigherselectivitytomethanolformationcomparedtotheCu-Celectrode,whichwasattributedtothehigherparticlesizeoftheformerandlowerCuO/Curatio.Theobtainedresultsshowpotentialinterestforthepossibleuseofelectrical「enewableenergyforthetransformationofCO2intovaluableproductsusinglowmetalloadingCubasedelectrodes(0.5mgCucm2)preparedbysputtering.
简介:内容摘要改革开放以来,我国的经济迅速发展,在大型铸件铸造方面,铸造技术和铸造方法随着经济的发展也处于不断的创新中,在这个过程中,铸件会出现气孔、缩松、裂纹等各种缺陷,影响铸件的机械性能和使用安全,通常可以将缺陷清除后,选择相同、相似或者更优的焊材进行铸件补焊。针对以上问题,本文对手工电弧焊与二氧化碳气体保护焊进行了详述的概括,分析讨论了二者的优缺点,并且通过实验,在保证了试块拉伸、弯曲、冲击、硬度等机械性能的情况下,针对不同的焊块类型,确定出合理的焊接工艺及相应的焊后热处理方法,并且研究了手工电弧焊与二氧化碳气体保护焊相结合的创新方法,一定程度上增强了焊铸的效率,为铸件缺陷补焊工作提供了有力的技术支持。
简介:Monoclinicparacetamol(PA)isnotoriousasapoorlycompactiblemodeldrug.Polyvinylpyrrolidone(PVP)isapolymerthatcanactasaneffectivebindertoimprovethemechanicalpropertiesofPA.ItissurprisinghoweverthattheroleofmixingconditionsonthephysicochemicalandmechanicalpropertiesofPA-PVPmixtureshasnotbeenreportedpreviously.TheresultsofthisworkshowedthatPA-PVPmixturescontaining5%(w/w)PVPpreparedusinghighenergymixingconditionshadconsiderablysmallerparticlesizedistributionsandhighercohesivitiesthanmixturespreparedusinglowenergymixingconditions.Solid-stateanalysisdidnotdetectanychangeinthemonocliniccrystallineformofPAaftermixingwithPVP.ThefollowingrankorderoftabletabilityforPA-PVPmixtureswasobtainedaccordingtothemixingcondition:lowshear-mediumshear
简介:Purpose':Physicalactivity(PA)andfundamentalmotorskillsareimportantcomponentsofcurrentandfuturetrajectoriesofhealthinyoungchildren.Thisstudyexaminedtheeffectsofa5-weekmotorskillinterventiononpreschoolers,motorskillcompetenceandtheirPAbehaviorswhileparticipatinginthemotorskillinterventionoroutdoorfreeplay(recess).Methods'.Atotalof102preschoolersservedasparticipantsandwerepartofamotorskillinterventiongroup(n=64)oracontrol/outdoorfreeplaygroup(n=38).Children'smotorskillswereassessedbeforeandaftertheinterventionusingtheTestofGrossMotorDevelopment-3rdedition.PAduringthemotorskillinterventionandoutdoorfreeplaywasassessedusingaccelerometersbothimmediatelybeforethestart(baseline,Week0orWeek1)andend(late.Week5orWeek6)oftheintervention.Results:Allchildrensignificantlyimprovedtheirmotorskillsfrombaselinetolateassessment(p<0.05).Childreninthemotorskillinterventiondemonstratedgreaterratesofchange(p<0.001)andscoredhigheronallmotorskillsatthelateassessmentcomparedwiththecontrolgroup(p<0.001).Therewasnoeffectofgroup(controlvs.intervention),buttherewasasignificanteffectofsexonchildren'sPAduringoutdoorfreeplayatbaseline(p<0.05).Similarly,therewasnoeffectofgrouponPAduringdayswiththemovementprogram(interventionvs.outdoorfreeplay)ateithertimepoint,butboysweremoreactivethangirlsatthelateassessment(p<0.05).Last,childrenintheinterventionengagedinmorePAwhileparticipatingintheinterventiontowardtheendoftheinterventionthanatthebeginning.Conclusion'.The5-weekmotorskillinterventionwaseffectiveatimprovingpreschoolers,motorskillsandratesofchangeinmotorskillswerehigherforchildrenwhocompletedtheinterventioncomparedwithchildreninthecontrolgroup.PreschoolersintheinterventiondiddemonstratePAchangeswhileparticipatingintheintervention,
简介:Step-edge-inducednucleationplaysakeyroleincontrollingthegrowthofnovelnanostructuresandlow-dimensionalmaterials.However,itisdifficulttoexperimentallydeterminethestepedgestructuresofcomplexmetaloxides.Inthiswork,wepresentadetailedtheoreticalstudyofthestabilityofstoichiometTicstepsonsapphire(OOOl).Basedonfirst-principlescalculationsandexcesschargecomputationbyFinnis1approach,apairofnon-polarstepedgesaredeterminedtobethemoststable.BystudyingtheadsorptioncharacteristicsofZnOandcombiningpreviousworks,wesuccessfullyexplainedhowgrowthtemperatureanddepositionrateaffectthein-planeorientationofZnOgrownonsapphire(OOOl).Theknowledgeonthestepedgestructuresandnucleationpatternswouldbenefitthestudyonstep-edge-guidednanostructuregrowth.
简介:Ininsects,thegustatorysystemplaysacrucialroleinmultiplephysiologicalbehaviors,includingfeeding,toxinavoidance,courtship,matingandoviposition.Gustatorystimulifromtheenvironmentarerecognizedbygustatoryreceptors.Todate,littleisknownaboutthefunctionofgustatoryreceptorsinagriculturalpestinsects.Inthisstudy,weclonedasugargustatoryreceptorgene,N/Gr11,fromthebrownplanthopper(BPH),Nilaparvatalugens(Stal),aseriouspestofriceinAsia;wethenidentifieditsligands,namely,fructose,galactoseandarabinose,bycalciumimagingassay.AfterinjectionofN/Gr11doublestrandedRNA,wefoundthatthenumberofeggslaidbyBPHdecreased.Moreover,wefoundthatN/Gr11inhibitedthephosphorylationofadenosinemonophosphate-activatedproteinkinase(AMPK)andpromotedthephosphorylationofproteinkinaseB(AKT).ThesefindingsdemonstratedthatN/Gr11couldacceleratethefecundityofBPHthroughAMPK-andAKT-mediatedsignalingpathways.Thisisthefirstreporttoindicatethatagustatoryreceptormodulatesthefecundityofinsectsandthatthereceptorcouldbeapotentialtargetforpestcontrol.