简介:摘要目的对血尿酸水平与冠心病的内在关联性进行评价.方法随机选取282例在我院进行冠状动脉造影的患者,并根据造影结果的不同分为两组,即冠心病组以及对照组.然后将冠心病组再分为A、B、C三个亚组来评价患者病情的严重程度,分组依据为冠脉评分标准.测定各组之间的血尿酸水平以及血糖、纤维蛋白等其他相关指标.冠心病的发生与血尿酸之间是否具有内在关联的评价采用logistic回归分析.结果比较血尿酸水平,冠心病组明显高于对照组,B、C两个亚组高于A亚组,P均<0.05.logistic回归分析表明冠心病的发生与血尿酸水平之间没有独立的相关性.结论若患者患有冠心病则其血尿酸水平相比于其他患者要偏高,并且血尿酸的水平会随着患者病变的严重度增加而升高.血尿酸水平与冠心病的发生之间并没有独立的相关性,其两者之间的关联可能是由于其他因素之间的作用引起的.关键词血尿酸水平;冠心病;内在关联性AssociationbetweenserumuricacidandcoronaryheartdiseaseDepartmentofCardiology,Ya'anPeople'sHospitalYa'anSichuanChinaRenPing625000AbstractObjectiveTherelationshipbetweenserumuricacidlevelandcoronaryheartdisease.MethodRandomlyselected282patientswithcoronaryangiogGraphyinourhospital,andaccordingtotheresultsofthecontrastofthetwogroups,thatis,thecoronaryheartdiseasegroupandthecontrolgroup.ThenthecorGonaryheartdiseasegroupwasfurthersubdividedintoa,B,Cthreesubgroupstoevaluatetheseverityofthepatient'sconditionandgroupaccordingtocoronaryscoringcriteria.Blooduricacidlevelsandotherrelatedindicators,suchasbloodglucoseandfibrin,weremeasured.ThecorrelationbetweentheoccurrenceofcorGonaryheartdiseaseandserumuricacidwasanalyzedbylogisticregressionanalysis.ResultTheserumuricacidlevelandcoronaryheartdiseasegroupweresignifiGcantlyhigherthanthoseinthecontrolgroup,theBandCtwosubgroupswerehigherthanthoseintheAsubgroup,andthePwaslessthan0.05.LogisticregresGsionanalysisshowedthattherewasnocorrelationbetweentheoccurrenceofcoronaryheartdiseaseandserumuricacidlevel.ConclusionIfpatientswithcoronaryheartdisease,theirserumuricacidlevelscomparedtootherpatients,andthelevelofserumuricacidwiththeincreaseintheseverityofthedisease.Therewasnoindependentassociationbetweenserumuricacidlevelandtheoccurrenceofcoronaryheartdisease.ThecorrelationbetweenserumuricacidandcoronaryheartdisGeasemKaeyybweocradusedbyotherfactors.Serumuricacidlevel;coronarydisease;Intrinsiccorrelation中图分类号R446.1文献标识码B文章编号1008-6315(2015)12-0848-01