简介：Eccentricphoto-refractionusuallyisusedasearlyeyesightdiagnostictestofinfantsandsmallchildren.Unlikecurrentlyapprovedgeometricalopticalmodelofeccentricphotorefractometer,thecrescentformationandthelight-intensitydistributioninthepupilimageofamyopiceyeareanalyzedbyFourieropticswiththeassumptionofanisotropicscatteringretina.Inthecaseoflittlecircularlightsourceandrectangularslit,thesimulationresultsofdifferentmyopicdioptersareobtainedbygeometricalopticaltheoryandFourieropticsrespectively.ItisfoundthatthesimulationresultsbyFourieropticsaresimilarasthoseobtainedbygeometricaloptics,andallsimulationsarealmostcorrespondingtotheexperimentalresult.Theresultdemonstratesthatthenewmethodpresentedhereisfeasible.

简介：microRNA（miRNA）是近年来发现的一类长度为19—25个核苷酸的非编码小分子RNA。它主要通过与靶目标基因3’非翻译区的完全或不完全配对，降解靶目标基因mRNA或抑制其翻译，从而参与调控个体发育、细胞凋亡、增殖及分化等生命活动。实验证据表明，miRNA可通过调控其靶基因参与的信号通路，影响肿瘤的发生和发展，发挥着类似于癌基因或抑癌基因的功能。本文就miRNA的生物学功能、miRNA与肿瘤发生的关系、癌症相关的主要miRNA和癌症治疗的展望等问题进行了概括性的论述。

简介：Thebasicideaofthefiniteelementbeampropagationmethod(FE-BPM)isdescribed.Itisappliedtocalculatethefundamentalmodeofachannelplasmonicpolariton(CPP)waveguidetoconfirmitsvalidity.Boththefielddistributionandtheeffectiveindexofthefundamentalmodearegivenbythemethod.Theconvergencespeedshowstheadvantageandstabilityofthismethod.Thenaplasmonicwaveguidewithadielectricstripdepositedonametalsubstrateisinvestigated,andthegroupvelocityisnegativeforthefundamentalmodeofthiskindofwaveguide.Thenumericalresultshowsthatthepowerflowdirectionisreversetothatofphasevelocity.

简介：Asimplifiedmodalmethodtoexplaintheresonancephenomenoninguidedmoderesonance(GMR)gratingswithasymmetriccoatingsispresented.Theresonanceobservedisduetotheinteractionoftwopropagationmodesinsidethegrating.Thereflectivityspectraandelectricfielddistributionscalculatedfromthesimplifiedmodalmethodarecomparedusingrigorouscoupled-waveanalysis(RCWA).Theinfluencesofhigh-orderevanescentmodesontheresonancepeakareanalyzed.AmatrixFabry-Perot(FP)resonanceconditionisdevelopedtoevaluatetheresonancewavelength.AnexplanationfortheresonancephenomenonobservedbasedontheFPresonancephaseconditionisalsoproposedanddemonstrated.ThesimplifiedmethodprovidesclearphysicalinsightsintoGMRgratingsthatareusefulfortheanalysisofavarietyofotherresonancegratings.

简介：Quantumkeydistribution(QKD)isamajorresearchtopicbecauseitprovidesunconditionalsecurity.Unfortunately,manyimperfectionsremaininQKD’sexperimentalrealization.TheFaraday–Michelson(FM)QKDsystemisproposedtoeliminatetheseimperfectionsusingpolarization.However,thelongarm’sphasemodulator(PM)hasanunexpectedinsertionloss,meaningthatthestatesentisnolongerperfect.Inthisletter,weproposeanalternativeFM-QKDsystemstructure,andanalyzethesecurityandkeygenerationrateincomparisonwiththeoriginalsystemviadifferentanalysismethods.WefindanobviouskeyrateimprovementwhenthePMinsertionlossisnotextremelysmall.

简介：Areal-timetwo-dimensional(2D)triangulationrangefinderispresented,whichiscomposedoftwolinearcomplementarymetaloxidationsemiconductor(CMOS)chips,twocameralenses,andfourlightemittingdiodes(LEDs).Thehighorderdistortioninimageaberrationsisthemainfactorresponsibleforthecoarseerrors.Thetheoreticalpredictionisingoodagreementwithexperimentsandthecorrectionequationisusedtoobtainmorereliableresultswiththeuniquedistortioncoefficientinthewholeworkingregion.

简介：Apavementreflectancemeasurementsystemisestablishedbasedonagonio-photometerexistingbychangingabrackettocarrytheroadsampleandluminancemeter,addingacollimatedlightsourcetoprovideincidentlight.Thisautomatedsystemcouldfinishthereflectionmeasurementofaroadsamplein4h.AnuncertaintybudgetofthismeasurementsystemismadeandthecombinedstandarduncertaintyofQ0is5.26%.

简介：Therelativebandgapforarhombuslatticephotoniccrystalisstudiedbyplanewaveexpansionmethodandhighfrequencystructuresimulator(HFSS)simulation.GeneralwavevectorsinthefirstBriliouinzonearederived.Therelativebandgapasafunctionofair-fillingfactorandbackgroundmaterialisinvestigated,respectively,andthenatureofphotonicbandgapfordifferentlatticeanglesisanalyzedbythedistributionofelectricenergy.Theseresultswouldprovidetheoreticalinstructionfordesigningopticalintegrateddevicesusingphotoniccrystalwitharhombuslattice.

简介：Thefingerjointlinesdefinedasfingercreasesanditsdistributioncanidentifyaperson.Inthispaper,weproposeanewfingercreasepatternrecognitionmethodbasedonLegendremomentsandprincipalcomponentanalysis(PCA).Afterobtainingtheregionofinterest(ROI)foreachfingerimageinthepreprocessingstage,LegendremomentsunderRadontransformareappliedtoconstructamomentfeaturematrixfromtheROI,whichgreatlydecreasesthedimensionalityofROIandcanrepresentprincipalcomponentsofthefingercreasesquitewell.Then,anapproachtofingercreasepatternrecognitionisdesignedbasedonKarhunen-Loeve(K-L)transform.ThemethodappliesPCAtoamomentfeaturematrixratherthantheoriginalimagematrixtoachievethefeaturevector.Theproposedmethodhasbeentestedonadatabaseof824imagesfrom103individualsusingthenearestneighborclassifier.Theaccuracyupto98.584%hasbeenobtainedwhenusing4samplesperclassfortraining.Theexperimentalresultsdemonstratethatourproposedapproachisfeasibleandeffectiveinbiometrics.

简介：Scalefactorofaconstantratebiasedringlasergyro(RLG)isstudiedboththeoreticallyandexperimentally.Byanalyzingexperimentaldata,wefindthattherearethreemaintermscontributingtothescalefactordeviation.Oneofthemisindependentoftime,thesecondvarieslinearlywithtimeandthethirdvariesexponentiallywithtime.Theoreticalanalysesshowthatthefirsttermiscausedbyexperimentalsetup,thesecondandthethirdarecausedbyun-uniformthermalexpensionandcavitylossvariationoftheRLG.

简介：Thereappeartobethreeprincipleforcesdrivingthefutureofnewdrugdevelopment:under-standingthegenome-transcrip-tome-protemecorrelations,under-standingandmappingproteinposttrans-lationalmodification(PTM)pathways,andintegrationofmassspectrometry(MS)techniquesintoroutineproteinidentificationandcharacterization.

简介：我们表明电的敲击笔记分析和一个连续波浪(cw)锁在3THz(100m)附近射出的兆兆赫量串联激光(QCL)的收音机频率(RF)注射。在免费的跑，QCL的敲击笔记频率与增加开车电流显示出180MHz的移动。敲击笔记，调整反应，拉的注射，和兆兆赫排放光谱在不同当前的政体的特征我，II，和III被调查。结果证明在我关上到激光阀值的当前的政体，我们在洞双程票频率获得RF调整的更狭窄的敲击笔记和扁平的反应。拉的效果并且光谱调整大小在当前的政体验证那我锁住的RF注射是有效的更多和一个柔韧的工具调制模式数字和兆兆赫QCL的模式频率。

简介：Influenceofthermal-mechanicalpropertiesonthefeaturesofthepandapolarization-maintainingopticalfiber(PMF)infabricationprocessisstudiedindetailbyfiniteelementmethod(FEM).Thestressbirefringenceis2.13443×10-4obtainedbythestaticanalysisand2.1269×10-4bydynamicanalysis.Thedifferenceinsimulationbytwomethodsisaround0.4%.Thenon-uniformityofstressbirefringenceinthefibercoreisabout1.6%.Predictedresultsdemonstratethateffectofthethermalconductiveparameteronfiberthermalstressdominates.Thehighanduniformstressbirefringenceinthefibercoreisobtainedbyappropriatelyselectingsuitablestressregionareaandposition.

简介：Anumericaldesignonthetriangularphotoniccrystalfiber(PCF)basedbackwardmulti-pumpRamanamplifierispresented.ItisdemonstratedthathighflatRamangaincanbereachedbasedonPCF.InfluencesofdifferentgeometricparametersandgermaniumdopingconcentrationsontheRamannetgain,amplifiedspontaneousemission(ASE)noiseanddoubleRayleighbackscattering(DRBS)ofthesignalhavebeenanalyzed.ForoptimizingcrystalfiberRamanamplifier(FRA),thereistradeoffbetweenthegeometricparameterandgermaniumdopingconcentrationoftriangularPCF.TheresultsshowthatPCFisanappropriatecandidateforhighgainRamanamplifiers.

简介：WeinvestigatethelateralshiftofaTM-polarizedlightbeamreflectedfromOttoconfigurationundergrazingincidence.Itisfoundthatthelateralshiftisstronglydependentonthethicknessoftheair-gaplayer.Byemployingthepole-nullrepresentation,wedemonstratethatthelateralshiftiscloselyrelatedtothenullofthereflectionfunction.ThenumericalsimulationsforaGaussianbeamareperformedtodemonstratethevalidityofourtheoreticalanalysis.

简介：很多研究采用分子信标技术来作为活体细胞中RNA表达研究的成像手段。然而,越来越多的证据表明,由于该技术易产生假阳性信号使得RNA的检测灵敏度显著降低。本文就如何克服这些缺陷,实现活体细胞中RNA的高灵敏检测来构建分子信标进行了阐述。

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简介：WhenfemtosecondlaserpulsesinterferewithchirpedfemtosecondlaserpulsesinAs2S3fiber,achirpedfibergratingisformed.Ananalyticalexpressionisgiventodescribethechirpedgrating,anditsBraggreflectivityiscalculated.BecauseofthehighphotosensitiveeffectofAs2S3material,thechirpedfibergratinghasawideBraggreflectivespectrumandhighreflectivitybychoosingproperparameters.Thisindicatesthatthechirpedfibergratingcanbeusedasastretcherinthefemtosecondchirpedpulseamplification(CPA)system.

简介：Thereisatradeoffbetweenthequantumefficiencyandthespectralresponselinewidthinresonant-cavityenhanced(RCE)photodetectors.Recentlyanewtypeofphotodetectorstructurehasbeenproposed,whichutilizesaninclinedmirrorinathree-mirrorcavity.Itdecouplesthequantumefficiencyandthespectralresponselinewidthandhashighresponsespeed,highquantumefficiency,andnarrowlinewidthsimultaneously.Theanalysisresultindicatesthatthelinewidthof0.8nmandquantumefficiencyhigherthan70%canbeachievedonthisdevice.Fora30×30μm2device,themaximumbandwidthapproaches23GHz.

简介：Wereportthedirectfabricationofamicrofluidicchipcomposedoftwohigh-aspectratiomicrofluidicchannelswithlengthsof3.5cmand8mminaglasssubstratebyfemtosecondlasermicromachining.Thefabricationmainlyconsistsoftwosteps:1)writingmicrochannelsandmicrochambersinaporousglassbyscanningatightlyfocusedlaserbeam;2)high-temperatureannealingoftheglasssampletocollapseallthenanoporesintheglass.Migrationofderivatizedaminoacidsisobservedinthemicrofluidicchannelbyapplyingelectricvoltageacrossthelong-migrationmicrochannel.