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500 个结果
  • 简介:摘要:目的 减少膈下游离气体误诊为胃肠道穿孔。方法 回顾分析一例腹部平片提示膈下游离气体患者误诊为胃穿孔的临床病例。结果 腹腔镜探查术中发现子宫穿孔,术后入重症医学科进一步观察治疗。三天后患者病情稳定,转妇产科治疗。

  • 标签: 膈下游离气体 胃肠穿孔 子宫脓肿穿孔 误诊
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  • 简介:摘要目的:探讨儿童不明原因发热的中医治疗思路,为临床治疗不明原因发热积累经验。方法:辨证论治,分析致病因素对症治疗。结果:该例病例好转出院。结论:对于此类不明原因发热的患儿治疗把握住阴液不足,阳气内盛的病机,以滋阴清热治疗会有好的疗效。

  • 标签: 午后潮热 滋阴清热 清骨散 蒿芩清胆汤
  • 简介:摘要:通过分析该儿童疑似新型冠状病毒肺炎患儿的临床资料,给患儿早期使用喜炎平、干扰素治疗,体温迅速下降,但病程中呼吸道症状反复,根据其临床表现与检查结果增加阿奇霉素治疗,在隔离治疗6天后患儿病情好转回家继续隔离服药治疗,疗程13天,门诊随访预后良好。结果:因目前尚无抗新型冠状病毒的特效药物,治疗中以对症治疗为主,早期抗病毒治疗,根据病情变化随时调整隔离治疗方案,能迅速有效地控制病情发展,阻止并发症的发生,缩短病程。

  • 标签: 儿童 疑似 新型冠状病毒肺炎
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  • 简介:摘要目的提高对创伤性肾动脉栓塞的诊治水平。方法回顾性分析本院收治的1例创伤性肾动脉栓塞的临床病例资料,就其临床表现、诊断及治疗进行讨论,结合复习相关文献。结果该例患者术中探查见腹膜后大量血肿及肾脏断裂伤,并行肾脏切除术。结论对于创伤性肾动脉栓塞,如果合并血流动力学不稳定,或出现肾性高血压,应及时行肾脏切除术。

  • 标签: 肾动脉梗阻 创伤和损伤
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  • 简介:摘要报告1例垂体功能减退致婴儿胆汁淤积性肝病,探讨内分泌激素在胆汁淤积性肝病中的作用及发病机制。通过总结临床特征、实验室、病理及基因检测结果,就肝细胞胆管膜面相关转运蛋白研究其表达是否正常,发现婴儿胆汁淤积伴低血糖应警惕垂体功能减退,皮质激素可能通过下调胆盐输出泵功能致胆汁淤积的发生。

  • 标签: 胆汁淤积 垂体功能低下 胆盐输出泵
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  • 简介:摘要67岁女性患者,发现右后胸部肿块6月余。肺增强CT检查示右侧第9/10后肋间隙水平胸壁内见卵圆形、结节状密度灶,边界清,大小约1.8 cm×2.2 cm,可见浅分叶,增强后见明显不均匀强化。2019年7月在全麻下行右侧胸壁肿块切除术+胸壁修补术,病理诊断为SMARCA4缺失的胸部肉瘤。术后随访2个月,肿瘤未见复发和远处转移,患者至上海市肿瘤医院进一步治疗。SMARCA4缺失的胸部肿瘤侵袭性强,易发生远处转移,确诊需依赖组织病理学、免疫组织化学或SMARCA2基因检测。其治疗原则首选根治性手术,术后辅助放、化疗等综合治疗。

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  • 简介:【摘要】总结 1 例失血性休克患者的护理 经验。 护理要点: 失血性休克 患者的抢救过程中对于生命体征的监控非常关键,需要全程密切监控患者的生命体征,及时合理的进行补液,维持各项体征的稳定,并且在患者治疗期间注意对下肢深静脉血栓、坠床等护理,为患者提供更加全面的护理。同时护理中注意做好病情的观察与监控,包括神志、尿量变化等,并进行详细记录,一旦发生休克征象则立即准备相应的抢救措施,配合医生完成抢救工作,在药物使用期间则监控血压值,结合血压变化情况调整药物浓度以滴速等,防止药物外渗。

  • 标签: 失血性休克 护理 措施
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  • 简介:AbstractBackground:Degree of mucosal recovery is an important indicator for evaluating the therapeutic effects of drugs in treatment of inflammatory bowel disease (IBD). Increasing evidences has proved that tight junction (TJ) barrier dysfunction is one of the pathological mechanisms of IBD. The aim of this study was to observe whether enhancement of TJ can decrease colitis recurrence.Methods:Eighty C57BL/6 mice were randomly divided into four groups including normal group, colitis group, sulfasalazine (SASP) treated group, and traditional Chinese drug salvianolic acid B (Sal B) treated group. Colitis was established in mice by free drinking water containing dextran sulfate sodium, after treatments by SASP and Sal B, recombinant human interleukin-1β (IL-1β) was injected intraperitoneally to induce colitis recurrence.Results:Compared with sham control, cell apoptosis in colitis group was increased from 100.85 ± 3.46% to 162.89 ± 11.45% (P = 0.0038), and TJ dysfunction marker myosin light chain kinase (MLCK) was also significantly increased from 99.70 ± 9.29% to 296.23 ± 30.78% (P = 0.0025). The increased cell apoptosis was reversed by both SASP (125.99 ± 8.45% vs. 162.89 ± 11.45%, P = 0.0059) and Sal B (104.27 ± 6.09% vs. 162.89 ± 11.45%, P = 0.0044). High MLCK expression in colitis group was reversed by Sal B (182.44 ± 89.42% vs. 296.23 ± 30.78%, P = 0.0028) but not influenced by SASP (285.23 ± 41.04% vs. 296.23 ± 30.78%, P > 0.05). The recurrence rate induced by recombinant human IL-1β in Sal B-treated group was significantly lower than that in SASP-treated group.Conclusions:These results suggested a link between intestinal mucosal barrier dysfunction, especially TJ barrier dysfunction, and colitis recurrence. The TJ barrier dysfunction in remission stage of colitis increased the colitis recurrence. This study might provide potential treatment strategies for IBD recurrence.

  • 标签: Colitis Inflammatory bowel disease Recurrence Tight junctions
  • 简介:摘要Bub1通过参与组装纺锤体组装检查点(SAC)以保证姐妹染色单体正确分离。Bub1异常表达可导致SAC功能缺陷,增加染色体不稳定性及非整倍体细胞的发生率。近年来研究发现Bub1在多种恶性肿瘤中呈异常表达,并通过影响肿瘤细胞增殖、侵袭、迁移及肿瘤干细胞活性等参与恶性肿瘤发生发展。进一步了解Bub1在恶性肿瘤中的作用机制有望为肿瘤靶向治疗提供新方法。

  • 标签: 肿瘤 Bub1