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500 个结果
  • 简介:Theeffectandmechanismofcarmustine(BCNU)combinedwithall-transretinoicacid(ATRA)ontheapoptosisofhumanglioblastomaU251cellswereinvestigatedbymeansof3-(4,5-dimethylthiazol-2-yl)-2,5-diphe-nyltetrazoliumbromide(MTT)assay,flowcytometry,reversetranscription-polymerasechainreaction(RT-PCR)andWesternblotanalysis.TheresultsshowthatBCNUorATRAshowstime-anddose-dependentinhibitioneffectsonhumanglioblastomaU251cellsandthecombinationofBCNUwithATRAshowsansynergisticinhibitioneffectonhumanglioblastomaU251cells,andthecombinedBCNUandATRAcansignificantlyinhibittheproliferationofhumanglioblastomaU251cells,andinducetheapoptosisofthem,makingthecellsarrestinthestageofG1phase,thestageofSandG2phasesdecline,therateoftheapoptosisofhumanglioblastomaU251cellsincrease,thecorrespondingmRNAexpressionofcyclinEandcyclin-dependentkinase2(CDK2)downregulatedandthecorrespon-dingmRNAexpressionofp27kip1unregulated.Inaddition,thecombinedBCNUandATRAreducedtheproteinexpressionofnuclearfactorkappaB(NF-κB).Takentogether,theseresultssuggestthatthetreatmentofhumanglioblastomaU251cellswithacombinationapplicationofATRAandBCNUcanexertsynergisticeffect,thecourseofthiskindofcombinationchemotherapymaylikelybeassociatedwithmultiplemolecularmechanismsforapoptosis,furthermore,thecyclinEandp27kip1shouldbeconsideredasnoveltargetsforcontrollingthegrowthofglioblastomacells.

  • 标签: 全反式维甲酸 脑胶质瘤 细胞凋亡 细胞周期素 卡莫司汀 细胞周期蛋白依赖性激酶
  • 简介:ThespectrumoftheΣ(1193)excitedstates,Σ,withisospinI=1andstrangenessS=??1isoneofthemostimportantissuesinhadronicphysics.TheΣresonancesaremostlyproducedandstudiedinK-inducedreactions.ManyΣresonancesarenowcatalogedbytheParticleDataGroup[1].However,ourknowledgeoftheseresonancesisstillverypoor.Intheenergyregionbelow2GeV,onlyafewofthemarewellestablished,suchastheΣ(1385)ofspin-parityJP=3=2+,Σ(1670)ofJp=3=2??andΣ(1775)ofJp=5=2??.Theothersarenotwellestablishedandsomeofthemareevenoflargeuncertaintiesontheirexistence.Thus,thestudyoftheΣresonancewiththeavailableexperimentaldataisnecessary.

  • 标签: EXPERIMENTAL Π now OUR is
  • 简介:SomecharacterizationsoftheconditionalexpectationoperatorsonLebesgue-BochnerspacesL_p(μ,X)aregiven,where1p<∞,p≠2.AlsoanexampleisgiventoshowthatthecharacterizationsoftheconditionalexpectationoperatorsonL_p(μ,X)aredifferentfromthatonL_p(μ)_zFinally,arepresentationoftheconstant-preservingcontractiveprojectiononspacesL_p(μ,X)isgotwhen0<p<1.

  • 标签: preserving EXPECTATION OPERATORS Radon CONDITIONAL LEBESGUE
  • 简介:<正>LetD={z∈:|z|<1}andφbeanormalfunctionon[0,1).Forp∈(0,1)suchafunctionφisusedtodefineaBergmanspaceA~p(φ)onDwithweightφ~p(|·|)/(1-|·|~2).Inthispaper,thedualspaceofA~p(φ)isgiven,fourcharacteristicsofCarlesonmeasureonA~p(φ)areobtained.Moreover,asanapplication,threesequenceinterpolationtheoremsinA~p(φ)arederived.

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  • 简介:Letp(z)=beapolynomialdegreenandletThenaccord-ingtoBernstein’sinequality||p’||p||.ItisawellknownopenproblemtoobtaininequalityanalogoustoBernstein’sinequalityfortheclassIInofpolynomialssatisfyingp(z)≡znp(1/z)HereweobtainaninequalityanalogoustoBernstein’sinequalityforasubclassofIInOurresultsincludeseveraloftheknownresultsasspecialcases.

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  • 简介:InthispaperwestudytheconvergencenfaclassofmeansonHp(G)(0<p<1),themeanstaketheBochner-Rieszmeansin[1],thegeneralizedBochner-Rieszmeansin[2],andtheoperatorsTΦrin[3]asspecialcases.Weobtainweak-typeestimatesfortheassociatedmaximaloperatorsandthemaximalmeanboundednessforthemeans.

  • 标签: operators maximal RIESZ CLASS estimates singular
  • 简介:在这份报纸,我们分类有限p组与确切顺序p的给定的结构的一A1亚群3。

  • 标签: 有限P-群 群阶 结构
  • 简介:Inthispaper,wegetW1,p(Rn)-boundednessfortangentialmaximalfunc-tionandnontangentialmaximalfunction,whichimprovesJ.Kinnunen,P.LindqvistandTananka’sresults.

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  • 简介:设α是正实数,[α0;α1,α2。…]是α的简单连分数;d是非平方整数,d1、d2是适合d1d2=d,1≤d11,d2)=1的正整数,本文证明了:当且仅当α=(d2/d1)(1/2)时,α=[α0α1,…αn-1,2α0],其中α0>0,αi=αn-1(i=1…,α-1).

  • 标签: 简单连分数 正整数 渐近分数 当且仅当 定理 引理
  • 简介:<正>WestudythesolvabilityoftheCauchyproblem(1.1)-(1.2)forthelargestpossibleclassofinitialvalues,forwhich(1.1)-(1.2)hasalocalsolution.Moreover,wealsostudythecriticalcaserelatedtotheinitialvalueu0,for1<p<∞.

  • 标签: P-LAPLACIAN equation STRONGLY NON-LINEAR SOURCES Existence
  • 简介:证明了指数型超椭圆方程x^2=p^2m-p^m+n+1无解(x,p,m,n),其中x,m,n∈N^+,m〉n〉1pP.上述结果部分解决了组合论中关于可逆Abel差集的Ma猜想.

  • 标签: 指数型超椭圆方程 正整数解 PELL方程
  • 简介:Inthispaperwewillshowthatifanapproximationprocess{Ln}n∈Nisshapepreservingrelativetotheconeofallk-timesdifferentiablefunctionswithnon-negativek-thderivativeon[0,1],andtheoperatorsLnareassumedtobeoffiniterankn,thentheorderofconvergenceofDkLnftoDkfcannotbebetterthann2evenforthefunctionsxk,xk+1,xk+2onanysubsetof[0,1]withpositivemeasure.Takingintoaccountthisfact,wewillbeabletofindsomeasymptoticestimatesoflinearrelativen-widthofsetsofdifferentiablefunctionsinthespaceLp[0,1],p∈N.

  • 标签: 渐近估计 N-宽度 线性相关 次可微函数 逼近过程 线性关系
  • 简介:Let(.theMuckenhouptclass).Inthispaper,theauthorintroducetheweightedHerz-typeHardyspaces(w2)andpresenttheiratomicdecomposition.Usingtheatomicdecomposition,theauthorfindouttheirdualspaces,establishtheboundednessonthesespacesofthepseudo-differentialoperatorsoforderzeroandshowthat,theclassofC(Rn)-functionswithcompactlysupport,isdenseinandthereisasubsequence,whichconvergesindistrbutionalsensetosomedistributionof,ofanyboundedsequenceinInaddition,theauthoralsosetuptheboundednessofsomenon-linearquantitiesincompensatedcompactness.

  • 标签: 量子
  • 简介:InthispaperwestudythetheoreticalpropertiesofmultigridalgorithmfordiscretizationofthePoissonequationin2Dusingamortarelementmethodundertheassumptionthatthetriangulationsoneverysubdomainareuniform.WeprovetheconvergenceoftheW-cyclewithasufficientlylargenumberofsmoothingsteps.ThevariableV-cyclemultigridpreconditionerarealsoavailable.

  • 标签: 多重网格算法 POISSON方程 收敛性 有限元法
  • 简介:混乱理论教了我们很可能有非线性和随机的输入愿望的一个系统生产不规则的数据。如果随机的错误是不规则的数据,那么随机的错误过程将提起非线性(Kantz和Schreiber(1997))。Tsai(1986)与AR(1)错误在线性模型为自相关和heteroscedasticity介绍了合成测试。刘(2003)与DBL在非线性的模型为关联和heteroscedasticity介绍了合成测试(p,0,1)错误。因此,在回归模型的重要问题是bilinearity,关联和heteroscedasticity的察觉。在这篇文章,作者与DBL讨论非线性的模型的更一般的大小写(p,q,1)由20测试的随机的错误。为bilinearity,关联,和heteroscedasticity的测试的几统计在简单矩阵公式被获得,并且表示。有线性错误的回归模型的结果与双线性的错误被扩大到那些。模拟学习被执行调查测试统计的力量。这篇文章的所有结果扩大并且发展结果Tsai(1986),魏,等(1995),和刘,等(2003)。

  • 标签: 非线性回归模型 随机误差 异方差性 相关性
  • 简介:Fluorescencepropertiesofaseriesofstyrene/p-divinylbenzene(St/p-DVB)copolymerbeadswereinvestigatedbysteady-statefluorescencespectra.Inadditiontothefluorescenceofthephenylringexcimer,anewemissionbandatca395nmappearswhenp-DVBcontentinfeedishigherthan13%(wt).Theintensityofthisnewemissionwasfoundtochangewithp-DVBcontentandtodecreasewithswollenbeads.Theoriginofthisnewemissionisconsideredtobeamulti-ringexcimerformation.

  • 标签: 聚合物网络 网状物 光物理研究 荧光性 苯乙烯 对乙烯苯
  • 简介:Thespectrumofisospin3/2Δ++(1232)excitedstatesisoneofthemostimportantissuesinhadronicphysicsandisattractingmuchattentionbecauseitisthemostexperimentallyaccessiblesystemcomposedofthreeidenticalvalencequarks.However,ourknowledgeontheseresonancesmainlycomesfromoldNexperimentsandisstillverypoor[1].Intheenergyregionaroundorabove2.0GeV,therearestillmanytheoreticalpredictionsofmissingΔstateswhichhavesofarnotbeenobserved.Searchingforthesemissingstatesfromotherproductionprocessesisnecessary.ApossiblenewexcellentsourceforstudyingtheseΔresonancecomprisesthe+p!K+Σ+(1385)andpp!nK+Σ+(1385)reactions,whichhaveaspecialadvantage,i:e:,thereisnocontributionsfromisospin1/2nucleonresonancesduetotheisospinandchargeconservations.

  • 标签: PP EXCELLENT ADVANTAGE source most is