简介:眼内病毒感染多由疱疹病毒家族导致。在免疫功能正常者中,以病毒性前葡萄膜炎与急性视网膜坏死综合征较为常见。对免疫功能低下者,有巨细胞病毒视网膜炎及进行性外层视网膜坏死,两者均发生在获得性免疫缺陷综合征(AIDS)后期。其他非AIDS患者,如白血病、器官移植、恶性肿瘤或自身免疫性疾病,因长期使用免疫抑制剂亦可发生巨细胞病毒视网膜炎。本文结合文献分别对上述眼内病毒感染性疾病进行叙述。
简介:AIM:Todeterminethenormativevaluesofwhite-towhitecornealdiameterwithOrbscanIITopographySystemandtocomparerightandlefteyesdatainthenormalyoungpopulation.METHODS:Atotalof1001healthyparticipantsaged18-45yparticipatedinthisobservationalcross-sectionalstudy.Thestudypopulationconsistedof616femaleand385malesubjects.ThecornealdiameterwasmeasuredwiththeOrbscanII.Thedifferencesbetweengenders,betweenrightandlefteyesandage-relatedchangeswereevaluated.StatisticalanalyseswereperformedusingStudent’st-test.RESULTS:Theaveragewhite-to-whitedistanceinourstudypopulationwasrecordedas11.65±0.36mm(median:11.60mm,mode:11.70mm,minimum:10.50mmandmaximum:13.60mm).Thewhite-to-whitedistancewas11.60±0.35mminmalesand11.71±0.36mminfemaleswhichwasstatisticallydifferentbetweengenders(P<0.01).However,white-to-whitedistancewasnotstatisticallydifferentbetweenrightandlefteyes.Inaddition,thisparameterdecreasedwithincreasingage.Considering95%confidenceinterval,cornealdiameterlessthan10.93mmandgreaterthan12.34mmwouldbeconsideredasmicrocorneaandmegalocornea,respectivelybasedonthisstudypopulation,usingtheOrbscanIItopography.CONCLUSION:DetaileddescriptionandanalysisofcornealdiameterwithOrbscandemonstratethattheobtainedaveragevalueofhorizontalwhite-to-whiteishigherinmalethanfemaleanddecreasesslightlywithincreasingage.Ourdataalsosuggeststhecutoffvaluesfordefinitionofmicrocorneaandmegalocornea,whichcanbeemployedwiththispopulation.