简介:【摘要】目的:一年一度宫颈癌项目工作的开展,分析农村35-64岁妇女宫颈癌筛查结果。在于尽早实施筛查,早发现、早预防、早治疗。为了深入了解农村35-64岁之间妇女宫颈癌的患病情况。方法:回顾性分析2017年1月至2019年12月接受宫颈癌筛查的800例农村妇女35-64岁资料,对其宫颈癌患病率与疾病知识认知程度进行分析。结果:800例农村妇女中,确诊阴道炎92例,细胞学异常22例,宫颈息肉14例,低级别病变12例,高级别病变5例,宫颈浸润癌2例,宫颈微小浸润癌2例。不同文化程度、经济收入的农村妇女,对宫颈癌的相关知识掌握程度存在差异,有统计学意义(p<0.05)。结论:农村妇女的宫颈癌患病率较高,受到经济条件、文化程度等因素影响,农村妇女的疾病认知程度相对较低,需要加强健康宣教,早期筛查、积极预防。
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简介:ToobservetheeffectofGardeniaextractZGontheadsorptionquantityofherpessimplexvirustype1(HSV-1)soastoexplorethemechanismofitsantiviralactivity,fluoresceinisothiocyanate(FITC)wasusedasthefluorescentprobetolabelvirusesandheparinsodiumwasusedascontrol.Meanwhile,theeffectofGardeniaextractZGontheadsorptionquantityonthesurfaceofHep-2cellswasdeterminedbyflowcytometry.ItwasdemonstratedthatadsorptionofHSV-1onthesurfaceofHep-2cellsexhibitedthecharacterofsaturationandspecificityandheparinsodiumcouldpreventattachmentofvirusesonthesecells.Theseresultsareinaccordwiththosereportedpreviously.Itwasalsoprovedthatthemannerofdrug-usepriortoadsorptionorsimultaneoususeofdrugandadsorptionwasbetterthanadsorptionpriortodrug-use,andtheinhibitionratesoftheformerandlattermannerwere84.76%and82.92%respectively.Threemannersofdrug-usewithGardeniaextractZGwerealleffectivetoreducetheadsorptionquantityofviruses,especiallythemannerofsimultaneoususeofdrugandadsorptionwithanadsorptioninhibitionrateof68.46%.Fromtheaboveobservation,itisapparentthatthemechanismofanti-viralactivityofGardeniaextractZGmaybeviaseveralstepsinvolvedintheHSV-1adsorption.
简介:WeareracingwithHIV-1,theetiologicagentforAIDSinhumanbeings[1,2],withtwopossibleendconsequences:ifwewin,HIV-1willbeunderourcontrolbyimmunologicortherapeuticmeasures;ifHIV-1wins,theSIVAfricanmonkeys'storywouldrepeatinhumans,i.e.,onlythefewindividualsthatarenotkilledbythevirus
简介:[摘要]通过护理一例颅内动脉瘤栓塞术后发生假性动脉瘤患者总结的护理经验。由此总结的护理要点:病人手术后要遵医嘱延长腹股沟穿刺点压迫时间,观察有无皮下血肿形成;加强宣教;用药指导;心理护理;疼痛护理;功能锻炼;出院指导,让病人早日回到家庭,融入社会工作学习。通过近两个月的治疗护理病人病情稳定,伤口愈合出院,出院后病人来院复查数次,状况良好。
简介:【摘要】:目的 分析 2017年望都县农村地区 6~ 17岁学生维生素 A营养状况。方法 采用多阶段分层与人口成比例的随机抽样方法 ,以我县农村送检的学生血清样本为研究对象 ,共抽取样品 280份 ,高效液相色谱法( HPLC法)测定血清视黄醇浓度 ,评价维生素 A营养状况。结果 我县 6~ 17岁农村学生血清视黄醇浓度为( 0.35±0.09) µg/mL,其中 6~ 11岁组血清视黄醇浓度分别为( 0.33±0.08) µg/mL ,显著低于 12~ 17岁组的 (0.38±0.09) µg/mL ( t=4.87, P<0.0005) 。维生素A缺乏率、边缘缺乏率分别为 2.14%、 25.36%; 6~ 11岁学生维生素 A边缘缺乏率为 32.74%,高于 12~ 17岁学生的 14.29%( P<0.05)。男女之间差异均无统计学意义( P>0.05)。结论 本县农村地区学生的维生素 A缺乏轻度存在 ,但边缘缺乏情况较为严重。
简介:Wehavepreviouslydemonstratedtheabilityofmalariaparasitestointerferewithspecificimmuneresponses.CD4Tcellsspecifictoparasiteantigens,butnotCD4Tcellsspecifictoanirrelevantantigen,ovalbumin(OVA),aredeletedviaapoptosisduringmalariainfection.Itisofinterest,therefore,toinvestigatetheimmuneresponsesthatdevelopedfollowingvaccinationwiththe19kDacarboxylterminusofthemerozoitesurfaceprotein1(MSP119)inmicethathadpreviouslyexperiencedmalariainfection.Inthisstudy,pre-exposureofmicetoPlasmodiumyoeliielicitednativeanti-MSP119antibodyresponses,whichcouldbeboostedbyvaccinationwithrecombinantMSP119,Likewise,infectionofMSP119-primedmicewithPlasmodiumyoelii(P.yoelii)ledtoanincreaseofanti-MSP119antibodies.MSP119vaccinationofmalariapreexposedmiceorimmunizationbyinfection/cureofMSP119-primedmiceenabledthemicetosurvivechallengeinfection,withtheformergrouphavingslightlylowerparasitaemia.Thedatasuggestthatexposuretomalariainfectionprimesanaturalimmuneresponsewhichcanbeboostedbyvaccination.Thisinformationisrelevanttothedevelopmentofavaccineforuseinindividualslivinginmalaria-endemicareas.
简介:ToexplorethemechanismoftheinhibitionofHIV-1byMycoplasmafermerttans,culturesupernatantsandthallodicproteinsfromM.fermerttansPG18werepreparedandtheproteincomponentsofthesupernatantswerepurifiedwithhighperformanceliquidchromatography(HPLC).Theinhibitoryactivitiestoreversetranscriptase(RT)andthenucleaseactivitiesweredetected;theinfluenceofM.fermerttansonIL-10secretionbybothnormalandH1V-1infectedhumanPBMCweredetermined,andtheinhibitoryeffectofrhIL-10onH1V-1replicationwasdetectedwithEI,ISAmethod.Theresultsshowedthatthepurifiedproteinswithamolecularweightof67-100kDaor10-25kDashoweda36%or34%inhibitoryac-tivitytoRTandpartialnucleaseactivity.ThethallodicproteincouldinducebothnormalandH1V-1infectedPBMCtosecretIL-10remarkably,andtothelatter,thiseffectwasmoreapparent.WhilerhIL-10couldinhibitreplicationofH1V-1inPB-MCinvitroinadose-dependantmanner.ItconcludesthattheinhibitoryeffectoftheM.fermentansPG18culturesupernatantsonRTandthepromotingeffectofPG18thallodicproteinonIL-10secretioninPBMCexplainthemechanismsofinhibitiontoHIV-1byM.fermentansPG18.