简介:自发的术语劳动在包括cytokine生产和白血球渗入的myometrium与放大煽动性的事件被联系;然而,调整如此的事件的潜在的机制充分没被理解。我们由成长胎儿假设了子宫的墙的那机械段由子宫的myocytes通过各种各样的cytokines的版本便于外部白血球溢出进术语myometrium。人的myometrial房间(hTERT-HM)受到静态的机械段;调节段的媒介被收集并且分析了使用48-plexLuminex试金和ELISA。人的子宫的microvascularendothelial房间(UtMVEC-Myo)的房间粘附分子表示上的调节段的媒介的效果被量的聚合酶链反应(qPCR)和流动cytometry检测;测试leukocyte-endothelial相互作用的功能的试金:到endothelial房间和象THP-1monocytic房间的移植一样的标记calcein的主要人的neutrophils的transendothelial移植的白血球的粘附被萤光计估计。在vitro学习的水流证明机械段(i)直接由hTERT-HM细胞导致多重cytokines和chemokines的分泌物(IL-6,CXCL8,CXCL1,移植禁止的因素(MIF),VEGF,G-CSF,IL-12p70,bFGF和导出血小板的生长因素子单元B(PDGF-bb),P<;0.05);导致段的cytokines(ii)提高白血球粘附到包围的内皮细胞层子宫的微脉管系统由(iii)导致endothelial房间粘附分子的表示并且(iv)指导外部白血球的transendothelial迁居。(vi)抵销Chemokine抗体和用途广泛的chemokine禁止者堵住白血球移植。我们的数据从子宫的血容器为白血球招募提供机械规定的一个证明给myometrium,为白血球建议通常认为的机制在劳动和产后的复杂物期间渗透到子宫。
简介:REPLACEMENTOFARTERIESWITHePTFEVASCULARGRAFTSLINEDWITHCONFLUENTAUTOLOGOUSENDOTHELIALCELLSINNON-HUMANPRIMATESREPLACEMENTOFARTER...
简介:Electroacupuncture(EA)hasbeenclinicallyusedtotreatdepressionandhasresultedinfavorableeffectsinChina.However,resultsfromanimalstudiesandpathologydonotreflecttheinfluenceofelectroacupuncturetreatmentoninvivophysiologicalfunctions.Tothoroughlyanddynamicallyobservepathologicalchangesduringdepression,thepresentstudyestablishedEA+fluoxetineandfluoxetinegroupstoobservedepressioninpatients.1H-magneticresonancespectroscopywasutilizedtodeterminethecorrelationbetweenhippocampalfrontallobemetabolitechangesandmentaldisorderscale.ResultsrevealedsignificantlyincreasedN-acetylaspartate(NAA)/creatine(Cr)inthebilateralhippocampusandrightfrontallobeofdepressionpatientstreatedwithEAcomparedwithfluoxetine.ChangesinNAA/Crinbilateralhippocampusandrightfrontallobeinbothgroups,beforeandaftertreatment,negativelycorrelatedwithseverityandcurativeeffects.Choline/Crchangesinthebilateralfrontallobesofbothgroupsweresignificantbeforeandaftertreatment,butnegativelycorrelatedwithcurativeeffects.Choline/CrchangesinthebilateralhippocampusweresignificantintheEA+fluoxetinegroupbeforeandaftertreatment,butnegativelycorrelatedwithseverityandthecurativeeffectsofdepression.Theseresultsdemonstrateabnormalbiochemicalmetabolisminbilateralfrontallobesandhippocampusofdepressionpatients,andshowthatEAsignificantlyalteredbiochemicalindicesinthefrontallobesandhippocampuscomparedwithfluoxetine.
简介:Inthispaper,wedescribehowtoconstructarealanti-symmetric(2p-1)-bandmatrixwithprescribedeigenvaluesinitsρleadingprincipalsubmatrices.Thisisdoneintwosteps.First,ananti-symmetricmatrixBisconstructedwiththespecifiedspectraldatabutnotnecessaryabandmatrix.ThenBistransformedbyHouseholdertransformationstoa(2ρ-1)-bandmatrixwiththeprescribedeigenvalues.Analgorithmispresented.Numericalresultsarepresentedtodemonstratethattheproposedmethodiseffective.
简介:电影冷却是一项重要措施启用一台煤气的汽轮机并且从而的入口温度的增加,到改进它的全面效率。冷却剂在片或endwalls通过洞的spanwise排被逐出建立防护材料的一部电影。洞经常在下游的方向被使倾向并且产生一个肾旋涡。这是相反旋转的旋涡对,与在二个旋涡之间的一个向上的流动方向,它趋于上升离开表面并且局部地在对外面向片喂热空气。颠倒旋涡的旋转感觉颠倒这二个缺点进优点。在考虑盒子中,一个反肾旋涡用两个都使倾向的洞的二随后的排被产生有内错角的下游、偏航的spanwise。在以前的研究,我们执行了大旋涡的模拟(它集中了于充分狂暴的边界层)凉下来电影、比较的这个反肾旋涡他们到一个相应物理实验。现在的工作详细分析模仿的流动领域,在全体会议开始(在片或endwall内)通过直到有热边界层的混合的洞。识别在吝啬的流动并且在即时流动发现的旋涡的结构,我们主要使用2标准和显示的线积分卷绕旋转(LIC)技术部分优化。流动区域(冷却剂全体会议,洞,和边界层)随后被学习并且连接了到对方。在整个边界层追踪反肾旋涡,我们建议基于涡度的二个标准并且在LIC结果上。这使我们能在墙把喷气旋涡与冷却有效性联系,它是电影冷却的特色。
简介:Theproblemofananti-planeGriffithcrackmovingalongtheinterfaceofdissimilarpiezoelectricmaterialsissolvedbyusingtheintegraltransformtechnique.Itisshownfromtheresultthattheintensityfactorsofanti-planestressandelectricdisplacementaroundthecracktiparedepen-dentonthespeedoftheGriffithcrackaswellasthematerialcoefficients.Whenthetwopiezoelectricmaterialsareidentical,thepresentresultwillbereducedtotheresultfortheproblemofananti-planemovingGriffithcrackinhomogeneouspiezoelectricmaterials.
简介:AChina-EuropeinternationalforumontheConventionagainstTortureandOtherCruel,InhumanorDegradingTreatmentorPunishmentandtheoptionalprotocoltotheconventionwasheldinBeijingfromAugust12-13,2006.JointlysponsoredbytheResearchCenterfortheproceduralsystemandjudicialreformoftheRenminUniversityofChinaandtheGreatBritain-ChinaCentre,theforumwasattendedbymorethan100professionals,expertsandscholarsfromtheBritishembassyinChina,EuropeanCommissiondelegationtoChina,thehumanrightslawcenteroftheUniversityofEssexofBritain,theRightsPracticeofBritain,theMaxPlanckInstituteforFor-