简介：为了进一步加强数字图像处理技术在医学图像领域的应用，提供一种基于Canny算子的医用X光图像边缘检测方法。首先介绍边缘检测算法的理论基础，然后结合Ganny算子的实现过程，说明边缘检测的所遵循的基本原则，最后对该算法进行了实验验证。从实验的结果可以看出，这种方法对医用X光图像非常有效，对利用计算机进行图像处理有着重要的现实意义。

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简介：【摘要】目的：探讨分析颈椎病早期诊断中X光片的临床应用。方法：选取2020年1月~2021年1月期间我院诊断的26例颈椎病患者，所有患者均行X线检查，对比最终确诊结果，观察X线检查的诊断符合率，并分析各类型颈椎病的X线表现。结果：

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简介：摘 要：目的：研究CT结合X光片在颈椎病诊断中的价值。方法：选择2021年02月－2022年02月到本院治疗颈椎病患者100例作为观察对象，对全部患者实施CT与X光片诊断，评估诊断价值。结果：CT结合X光片组各项目诊断准确度均度高于X光片组，P＜0.05。结论：运用CT结合X光片诊断颈椎病价值较高，可运用。

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简介：AbstractBackground:Macrophages play an important role in renal ischemia reperfusion injury, but the functional changes of macrophages under hypoxia/reoxygenation and the related mechanism are unclear and need to be further clarified.Methods:The effects of hypoxia/reoxygenation on functional characteristics of RAW264.7 macrophages were analyzed through the protein expression detection of pro-inflammatory factors TNF-α and CD80, anti-inflammatory factors ARG-1 and CD206. The functional implications of C-X3-C motif chemokine receptor 1(CX3CR1) down-regulation in hypoxic macrophages were explored using small interfering RNA technology. Significance was assessed by the parametric t-test or nonparametric Mann-Whitney test for two group comparisons, and a one-way ANOVA or the Kruskal-Wallis test for multiple group comparisons.Results:Hypoxia/reoxygenation significantly increased the protein expression of M1-related pro-inflammatory factors TNF-α, CD80 and chemokine C-X3-C motif chemokine ligand 1 (CX3CL1)/CX3CR1 and inhibited the protein expression of M2-related anti-inflammatory factors ARG-1 and CD206 in a time-dependent manner in RAW264.7 cells. However, the silencing of CX3CR1 in RAW264.7 cells using specific CX3CR1-siRNA, significantly attenuated the increase in protein expression of TNF-α (P < 0.05) and CD80 (P < 0.01) and the inhibition of ARG-1 (P < 0.01) and CD206 (P < 0.01) induced by hypoxia/reoxygenation. In addition, we also found that hypoxia/reoxygenation could significantly enhance the migration (2.2-fold, P < 0.01) and adhesion capacity (1.5-fold, P < 0.01) of RAW264.7 macrophages compared with the control group, and CX3CR1-siRNA had an inhibitory role (40% and 20% reduction, respectively). For elucidating the mechanism, we showed that the phosphorylation levels of ERK (P < 0.01) and the p65 subunit of NF-κB (P < 0.01) of the RAW264.7 cells in the hypoxic/reoxygenation group were significantly increased, which could be attenuated by down-regulation of CX3CR1 expression (P < 0.01, both). ERK inhibitors also significantly blocked the effects of hypoxic/reoxygenation on the protein expression of M1-related pro-inflammatory factors TNF-α, CD80 and M2-related anti-inflammatory factors ARG-1 and CD206. Moreover, we found that conditioned medium from polarized M1 macrophages induced by hypoxia/reoxygenation, notably increased the degree of apoptosis of hypoxia/reoxygenation-induced TCMK-1 cells, and promoted the protein expression of pro-apoptotic proteins bax (P < 0.01) and cleaved-caspase 3 (P < 0.01) and inhibited the expression of anti-apoptotic protein bcl-2 (P < 0.01), but silencing CX3CR1 in macrophages had a protective role. Finally, we also found that the secretion of soluble CX3CL1 in RAW264.7 macrophages under hypoxia/reoxygenation was significantly increased.Conclusions:The findings suggest that hypoxia/reoxygenation could promote M1 polarization, cell migration, and adhesion of macrophages, and that polarized macrophages induce further apoptosis of hypoxic renal tubular epithelial cells by regulating of CX3CL1/CX3CR1 signaling pathway.

简介：摘要目的探究神经刺激器引导下臂丛神经阻滞在手外科手术中的应用效果。方法随机抽取我院外科自2015年2月至2016年6月收治的需要行手部或者前臂手术的患者30例，分为实验组和对照组，每组15例。对照组采用传统臂丛肌间沟神经阻滞，实验组采用神经刺激器引导下臂丛肌间沟神经阻滞。对比两组患者穿刺后的起效时间以及持续时间。结果实验组起效时间以及持续时间均优于对照组的，差异显著，具有统计学意义（P<0.05）。结论神经刺激器引导下臂丛神经阻滞在手外科手术中取得了显著的效果，一定程度的延长了麻醉时间，值得进一步推广和使用。

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简介：摘要目的比较0.5%罗哌卡因20mL，30mL，40mL在超声引导下腋路臂丛神经阻滞中的效果。方法选择符合条件的上肢手术患者75例，随机分为三组，A组20ml，B组30ml，C组40ml，均采用0.5%罗哌卡因，在超声引导下行腋路臂丛神经阻滞结果臂外侧上皮神经，臂内侧皮神经及前臂内侧皮神经阻滞起效时间A组明显长于C组（P<0.05），尺神经运动阻滞起效时间B组明显长于C组（P<0.05）。各组内腋神经运动阻滞起效时间明显长于其余运动神经阻滞起效时间（P<0.05）。阻滞维持时间A组，显著短于B、C两组（P<0.05)结论超声引导腋路臂丛阻滞综合考虑起效时间、阻滞效果及并发症，30ml局麻药量可能是较好的选择。

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