简介:摘要:目的分析人性化护理干预对晚期肿瘤患者化疗后并发症及胃肠道不良反应的影响。方法选取2018年1月~2020年1月本院80例患者作为研究对象,按照随机数字表法分为观察组(人性化护理)与对照组(常规护理)两组,每组40例。比较两组患者护理前后焦虑自评量表(SAS)评分、抑郁自评量表(SDS)评分、生活质量评定问卷(QOL)评分,以及患者满意度。结果两组患者SAS、SDS护理后评分均低于护理前评分,观察组护理后各项评分较对照组低(P<0.05);观察组护理后QOL评分较对照组改善更为显著(P<0.05);比较两组患者满意度,观察组较对照组高(P<0.05)。结论人性化护理应用于晚期肿瘤化疗患者,能够调整患者焦虑抑郁情绪、提高生活质量,降低并发症的发生,改善胃肠道不良反应有着突出效果,患者满意度高,可予以推广。
简介: 【摘 要】目的:探究他克莫司与环磷酰胺治疗狼疮性肾炎的的效果和用药不良反应率。方法:纳入观察对象 40例(均确诊为狼疮性肾炎)进行实验研究,研究时间从 2015年 3月直至 2019年 5月。采用随机分组法,将观察对象分为甲乙两组,甲组 20例患儿使用他克莫司治疗,乙组 20例患儿采取环磷酰胺治疗。观察对比两组患儿治疗效果、不良反应发生情况。结果:甲组中 1例患儿疗效不明显,另外 19例均有改善,总有效率 95%;乙组中 5例疗效不明显, 1例病情恶化,另外 14例病情改善,总有效率 70%,两组间进行比较后得到 P<0.05。治疗后随访观察到,甲组患儿 1例出现尿痛的不良反应,乙组中有 6例,两组不良反应发生率的差异显著( P<0.05)。结论:狼疮性肾炎患儿在治疗过程中可应用他克莫司与环磷酰胺进行治疗,对比发现,他克莫司可以明显提升治疗的有效率,并且控制了患儿不良反应的出现,治疗安全性得到保障,临床应用效果理想,值得推广。 【关键词】他克莫司 ;环磷酰胺 ;狼疮性肾炎 ;效果 ;不良反应率 [Abstract] Objective: To explore the effect and adverse reaction rate of tacrolimus and cyclophosphamide in the treatment of lupus nephritis. Methods: 40 patients (all diagnosed as lupus nephritis) were included in the experimental study. The study period was from March 2015 to may 2019. The observation objects were randomly divided into two groups, group A (20 cases) was treated with tacrolimus, and group B (20 cases) was treated with cyclophosphamide. The treatment effect and adverse reactions of the two groups were observed and compared. Results: in group A, the curative effect of 1 case was not obvious, the other 19 cases were improved, the total effective rate was 95%; in group B, the curative effect was not obvious in 5 cases, 1 case was deteriorated, the other 14 cases were improved, the total effective rate was 70%, the comparison between the two groups showed that P < 0.05. After treatment, 1 case of adverse reactions occurred in group A and 6 cases in group B. There was a significant difference in the incidence of adverse reactions between the two groups (P < 0.05). Conclusion: tacrolimus and cyclophosphamide can be used in the treatment of children with lupus nephritis. Compared with cyclophosphamide, tacrolimus can significantly improve the efficiency of treatment, and control the occurrence of adverse reactions in children. The safety of treatment is guaranteed and the clinical application effect is ideal, which is worthy of promotion.
简介:【摘要】 目的 评价医院-社区-家庭护理干预对稳定性冠心病患者经皮冠状动脉介入治疗(PCI)后心血管事件发生的影响。方法 本次研究将2020年1月-2020年12月本院接受PCI治疗的稳定性冠心病患者作为研究对象,随机抽签法分为两组,各40例。对照组接受常规护理,观察组实施医院-社区-家庭护理干预,对比两组护理效果及心血管事件发生率。结果 观察组患者心血管事件发生率低于对照组,本组患者生活质量评分均高于对照组(P