简介：Theproblemonthedynamicresponseofarigidembeddedfoundationinthepresenceofanundergroundrigidtunnelandsubjectedtoexcitationofincidentanti-planeSHwavesisanalyzed.Byusingtheexactanalyticalsolutionforthetwo-dimensionalSH-wavepropagationinandaroundboththesurfacerigidfoundationandsubsurfacerigidtunnel,thoseaspectsoftheresultinggroundmotionsthatareofspecialinterestandimportanceforseismicresistantdesigninearthquakeanalyseshavebeenexamined.Thecomputedamplitudesoftheresultingperiodicgroundmotionsdisplayaverycomplicatedwave-interferencebetweenthesurfacefoundationandundergroundtunnelthatleadtoobservedstandingwavepatterns,togetherwithabruptchangesinthewaveamplitudesandlargeamplificationoftheincidentmotions.

简介：无

简介：

简介：Inordertoinvestigatetherelationshipbetweenthetraceelementsandthecharacteristicsoftheoysters,weanalyzedthetraceelementspresentinthegermplasmofoystersfromdifferentproducingareasintheJiaozhouBay.Theelementfingerprintswereestablishedtoreflecttheelementalcharacteristicsoftheoysters.Concentrationpatternsoftheelementsweredecipheredbyprinciplecomponentanalysis(PCA)andhierarchicalclusteranalysis(HCA).ThesixregionswerediscriminatedwithaccuracyusingHCAandPCAbasedontheconcentrationof16traceelements.Theelementswereviewedascharacteristicelementsoftheoystersandthefingerprintsoftheseelementscouldbeusedtodistinguishthequalityoftheoysters.

简介：150casesofprolapseoflumbarintervetebraldiscwererandomlydividedintotreatmentandcontrolgroups.80casesintreatmentgroupweretreatedwithcombinationofacupuncture,oraladministrationofChinesemedicinalherbs,traction,point-injectionandintravenousdripofenergydehydrationmixture;70casesincontrolgroupweremanagedbycombinationofacupuncture,oraladministrationofherbalmedicines,traction,acupoint-injection(withoutenergydehydrationmixture).Theresultsshowedthatthecurativerateandthetotaleffectiverateofthetreatmentgroupwere91.25%and98.75%separately,whilethoseofthecontrolgroup62.86%and92.86%respectively.Comparisonofthecurativeratebetweenthe2groupsshowedaremarkablesignificance(P＜0.01).TheobservationdemonstratedthatcombinedtreatmentofprolapseoflumbarintervertebraldiscwithtraditionalChineseandWesternmedicineisaneffectiveapproach.

简介：Acutemyeloidleukemia(AML)isageneticallyheterogeneousmyeloidmalignancythatoccursmorecommonlyinadults,andhasanincreasingincidence,mostlikelyduetoincreasingage.PrecisediagnosticclassificationofAMLrequiresclinicalandpathologicinformation,thelatterincludingmorphologic,immunophenotypic,cytogeneticandmoleculargeneticanalysis.RiskstratificationinAMLrequirescytogeneticsevaluationasthemostimportantpredictor,withgeneticmutationsprovidingadditionalnecessaryinformation.AMLwithnormalcytogeneticscomprisesabout40%-50%ofallAML,andhasbeenintensivelyinvestigated.Thecurrentlyused2008WorldHealthOrganizationclassificationofhematopoieticneoplasmshasbeenproposedtobeupdatedin2016,alsotoincludeanupdateontheclassificationofAML,duetothecontinuouslyincreasingapplicationofgenomictechniquesthathaveledtomajoradvancesinourknowledgeofthepathogenesisofAML.ThepurposeofthisreviewistodescribesomeoftheserecentmajoradvancesinthediagnosticclassificationandriskstratificationofAML.

简介：

简介：无

简介：AbstractObjective:To investigate whether the fetal gender affects the incidence of pre-eclampsia (PE) and fetal growth restriction (FGR) in singleton and twin pregnancies.Methods:This was a 10-year single-center, retrospective, cohort study from January 2009 to January 2019. A total of 57,129 singleton and 3699 twin pregnancies aged between 18-55 years old were recruited at the Third Affiliated Hospital of Guangzhou Medical University, China. We used multivariable logistic regression to analyze the effect of fetal gender on the incidence of PE and FGR.Results:In singleton pregnancies, the incidence rates of PE and FGR with a female fetus were higher than those with a male fetus (6.4% (1713/26,793) vs. 5.9% (1803/30,336), P < 0.05 and 3.5% (932/26,793) vs. 2.4% (745/30,336), P < 0.05, respectively). A female fetus was an independent risk factor for either PE or FGR (adjusted odds ratio: 1.169 or 1.563; 95% confidence interval: 1.036-1.319 or 1.349-1.810, respectively). In twin pregnancies, the incidence of early-onset PE was greater in pregnancies with two females compared with two males or one male plus one female (4.6% (46/1003) vs. 4.1% (54/1305) vs. 2.4% (33/1391), P < 0.05). Female-female twins was an independent risk factor for PE (adjusted odds ratio: 1.367, 95% confidence interval: 1.011-1.849), especially early-onset PE.Conclusion:The female fetus was associated with PE in both singleton and twin pregnancies and was also a risk factor of FGR in singleton pregnancies.

简介：AbstractObjective:To evaluate the clinical utility of noninvasive prenatal screening (NIPS) for fetuses with congenital heart disease (CHD) and impact of NIPS results on pregnancy outcome.Methods:This was a retrospective study of pregnant women with fetuses diagnosed with CHDs by sonographic examination, who willing to underwent NIPS as a side-test for fetal aneuploidies. From August 2016 to October 2017, in the sonographic examination center of Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region. NIPS was offered to 117 women, 19-32 years old, who carried fetuses with CHD diagnosed by fetal ultrasound (mean gestational age= 24 weeks). The pregnancy outcomes were followed-up.Results:NIPS positive rate in our pregnancies with CHD fetuses’ cohort was 11.1% (13/117), and the positive predictive value for aneuploidies is 85.7% (6/7). In the NIPS positive group (n = 13), all pregnancies terminated, 76.9% (10/13) of those decisions were made on ultrasound finding alone. In the NIPS negative group (n= 104), 2 lost follow-up, 79 pregnancies terminated, among which 77.2% (61/79) of the decision was made by ultrasound results alone. Twenty-three pregnancies continued and 78.3% of those fetuses carried single type CHD. In terminated pregnancies that did not considered NIPS results (71/115), 73.2% (52/71) of those carried fetuses with two or more types of CHDs.Conclusion:NIPS can detect common aneuploidy associated with CHD with high positive predictive value and screening yield. The NIPS result played certain meaningful roles in determining pregnancy outcomes, particularly for fetus with simplex CHD; yet the parents’ decision of pregnancy was mainly made based on ultrasound findings.

简介：Thewide-shallowcompositebucketfoundation(WSCBF)isanewtypeofoffshorewindpowerfoundationthatcanbebuiltonlandandrapidlyinstalledoffshore,therebyeffectivelyreducingtheconstructiontimeandcostsofoffshorewindpowerfoundation.Inthisstudy,thehorizontalbearingcapacityiscalculatedbyfiniteelementsimulationandcomparedwithtestresultstoverifythevalidityofresults.Inthisprocess,theverticalloadandbendingloadarerespectivelycalculatedbythefiniteelementsimulation.Undertheverticalloadeffect,thebucketfoundationandthesoilinsideareregardedasawhole,andthecorrespondingbucklingfailuremodeisobtained.Theultimateverticalbearingcapacityiscalculatedusingempiricalandtheoreticalformulas;thetheoreticalformulaisalsorevisedbyfiniteelementresults.Underbendingload,therotationalcenterofthecompositebucketfoundation(inaregionclosetothebucketbottom)graduallymovesfromtheleftofthecentralaxis(reversetoloadingdirection)tothenearbycompartmentboardsalongtheloadingdirection.TheH–Menvelopelineshowsalinearrelationship,anditisdeterminedthattheverticalandbendingultimatebearingcapacitiescanbeimprovedbyanappropriateverticalload.

简介：2004年10月1日，北京塞尔瑟斯仪表科技有限公司正式加入HART基金会，成为其重要一员。塞尔瑟斯研发部自成立以来即不断开发出技术领先的产品，此次加入HART基金会意味着塞尔瑟斯已经积累了足够的技术力量来完成HART产品的开发，并决心在这个领域奋力一搏。

简介：Asaspecialgeologicalphenomenon,thecharacterofcollapsibleloessfoundationiscollapsiblewhenpenetratedbywater.Thischaracterleadstothesoillosingloadbearingcapacitylargelyandmayleadtofoundationfailure.Pileisapopularfoundationusedincollapsibleloess.Thesqueezedbranchandplatepileisanewtypeofpiledevelopedinrecentyearsandhasnotbeusedinaprojectbefore.Inthispaperthreesqueezedbranchandplatepilesaretestedincollapsibleloessafterimmersionprocessing.Theresultsmaybeusedforreferenceinsimilarconstructionproject,andtoprovidetheoreticalreferencesforde-signingofthesqueezedbranchandplatepilesinengineeringpractice.

简介：

简介：本刊讯11月21日．现场总线基金会中国市场委员会于2008年11月13日在广州华美达酒店成功举办了现场总线技术应用指导会议．吸引了200多位来自不同过程工业的用户涌跃参加。会议的亮点在于邀请了国内领先的企业用户分享他们的成功应用经验。内容囊括了采用基金会工厂自动化结构所获得的运行优势和经营收益。

简介：并且它符合人生三定律中的平衡稳定定律以及生存发展定律按照人生三定律之平衡稳定定理,对当事人双方都能得到人生平衡,对当事人双方都能得到人生平衡

简介：寻找一种恰当的方法帮助术者实施精确的肾盏穿刺是目前经皮肾镜碎石术（percutaneousnephrolithotomy,PCNL）研究的热点。来自广州中山三院的医师设计了一种独特的CTU辅助超声引导方案帮助术者按照预设的穿刺路径快速、安全的实施穿刺。

简介：无

简介：Type2cytokinesareusuallypredominantintumorpatientsandassociatedwithtumorprogression.Toexplorewhetherreversingoftype2predominancecouldbeapromisingstrategyintumorimmunotherapy,PBMCsof35lungcancerpatientsand19healthysubjectswerepreparedandsubjectedtobeexaminedforcytokinesecretionandgeneexpression.Tetra-Methylpyrazine(TTMP),extractedfromatraditionalChinesemedicinalherbwhichhasbeenusedinclinictoreversetheTh2statusofcancerpatientsinChina,wasaddedtoPBMCculture.DeterminedbyRT-PCR,thepositivepercentagesofmRNAexpressionoftype1cytokines(8.6%forIFN-γand11.4%forIL-2)werelowerthanthoseoftype2cytokines(71.4%forIL-4,60%forIL-6and80%forIL-10)inpatients'PBMCs.Thepotentialofgeneexpressing(measuredasrelativeintensitytotheratioofβ-actin)inthepatientsfortype1cytokineswasalsoinalowlevel(0.111forIFN-γ,0.119forIL-2)incomparisonwitharelativehighlevelfortype2cytokines(0.319forIL-4,0.303forIL-6and0.377forIL-10).Meanwhile,bothpositivepercentageandrelativeintensityofgeneexpressionwerelowerforatype1cytokine-relatedtranscriptionfactorT-bet(31.4%and0.142,respectively)thanthosefortype2cytokine-relatedGATA3(85.7%and0.378,respectively).ThebloodserumlevelsofIFN-γandIL-2inthepatientswereslightlylowerbutnotsignificantlywhencomparedwithhealthycontrol.Incontrast,thelevelsIL-4andIL-6inpatientsweresignificantlyhigherthanthoseinhealthysubjectsbyELISAanalysis.TTMPcouldenhancesupernatantconcentrationandgeneexpressionlevelsofIFN-γ,IL-2andT-bet,butreducedthoseoftype2cytokines.Theseresultsdemonstratethatthelungcancerpatientshadapredominantexpressionoftype2cytokinesandTTMPcouldreversethetype2dominantstatus,whichmightofferanalternativetherapeuticregimeforlungcancerpatients.Cellular&MolecularImmunology.2004;1(1):63-70.

简介：PulsediagnosisplaysavitalroleinTraditionalChineseMedicine(TCM).Toextracteffectiveandproperfeaturesfromthewrist-pulse-signalsisacrucialstepfortherecognitionandclassificationofthepulsesignals.Althoughtheanalysisinthetimedomainisalsoveryeffectiveforalotofpulsetypes(SHUetal.,2007),thefrequencyandtime-frequencyanalysisareusuallyusedintheliterature(YANetal.,2005;YUEetal.,2006)becausethepulsesignalsarenon-stationaryandnon-periodictimeseriesinthepathologicalstates.Inrecentyears,anewtime-frequencyanalysismethod,Hilbert-HUANGTransformproposedby