简介：0—2度脊椎前滑脱基本无明显症状，但是随着时间推移以及出现的一些影响背痛的因素，从而导致慢性下腰痛。标准的治疗方法为物理治疗和激素等非手术治疗，但有些患者因效果不佳需要手术治疗。AunobleS等介绍一种治疗0—2度脊椎前滑脱症的新技术：视频辅助下前路椎间融合和固定。选择慢性下腰痛2年以上并经非手术治疗效果不佳的20例患者，记录临床信息和根性痛情况。术前和术后（直至随访结束）应用Oswestry评分和可视性评分（visualanalogscoreVAS）对腿痛和腰痛进行评估。X线平片提示0度滑脱8名、1度滑脱10名、2度滑脱2名（根据Meyerding分类法）。所有病例手术途径均为前路视频辅助下经腹膜后途径，行椎间盘摘除术、植入前路椎间融合器（填塞自体髂嵴松质骨）、以及三角锥形钢板固定。在分别3个月、6个月、12个月和24个月后对患者的临床和影像学情况进行评估。结果：11例女性和9例男性，平均年龄39岁，BMI为25．6岁。所有患者的向前滑脱部位均在L5，平均滑移19％，7例L5椎体变异。失血量低于100ml。所有患者术后均给予8周的腰围固定。男性患者均未出现逆行射精，女性也未出现性功能异常。1例2度滑脱的患者疼痛无明显缓解，再手术行腰后路椎弓根螺钉固定。在2年的随访中有19例患者取得良好的融合（95％），Oswestry平均评分从术前的74％提高到术后随访结束时的21％，腰痛的可视性评分从6．5提高到2．7，而腿痛的评分是从6．2到3．4。在平均5．5个月内（6周到1年）有18例患者回到了工作岗位。结论：与后路椎间融合和固定技术相比，本技术的并发症发生率更低，而疗效相似。但2度以上滑脱患者似乎不太适合于本技术。从研究中可以看到本技术的主要优点在于避免了腰后背肌肉的损伤以及减少失血量而有利于术后恢复。

简介：Lactivicin,anovelinhibitorofbacterialcellwallsynthesis,wasisolatedfromtheculturefil-tratesofmicroorganismYK-258andYK-422.Itexhibitsbiologicalactivitiessimilartothoseoftheβ-lactamantibiotics,althoughitdoesnothaveaβ-lactamringinitsmolecule.Sincethediscoveryoflactivicin,hundredsofitsderivativeshavebeensynthesized.Most

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简介：Paget'sdiseaseofboneisafocaldisorderofboneremodellingcausedbyabnormallyincreasedosteoclast-mediatedboneresorption.qtleaffectedboneschangeinshaw,sizeanddirection,whiletherestoftheskeletonremainsnormal.TheclinicalconsequencesofthediseasewerefirstdescribedbySirJanlesPagetin1876(Figure1).

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简介：Objective:Toobservetheeffectofelectroacupuncture(EA)onMeniere'sdisease.Methods:Atotalof114cases(38malesand76females)ofMeniere'sdiseaseweretreatedwithEAofErmen(耳门TE21),Tinggong(听宫SI19),Tinghui(听会GB2),Yifeng(NFDB1风TE17),Fengchi(风池GB20)andBaihui(百会GV20).Thetreatmentwasgiven3timesaweek,9timesaltogether.Follow-upwasmadeattheendofthe3rd,6thand12thmonthsaftertreatment.Results:Follow-upin114patientsshowedthatafterEAtreatment,63cases(55.26%)werecured,30(26.31%)hadremarkableimprovementintheirsymptoms,10(8.77%)respondedwithimprovementand11(9.65%)failedinthetreatment,withatotaleffectiverateof90.35%.Conclusion:EAtreatmentwaseffectiveincontrollingMeniere'sdiseasepatients'symptomsandreducingattack.

简介：Therearemanycausesofpain.Generallyspeaking,inflammationisthemostcommoncause,followedbyinjury,ulceration,spur,chemicalstimulation,etc..Acupuncturehasitsuniqueeffectivenessoninflammationthatischaracterizedasredness,swelling,warmthandpain,includingneuritisandarthritis.

简介：Aim:Tostudypercutaneousabsorptionandmetabolismofketoprofenisopropylester(KPE)viaexcisednudemouse'sandmonkey'sskin.Methods:Excisedskinwaspreparedbysurgicalexcisionandenzymedigestion.Sideby-sidediffusioncellswereusedforinvitropermeationstudies.TheconcentrationsofKPEanditsmetaboliteinsampleswereassayedbyHPLC.Results:AllKPEpenetrationthroughwholethicknessskinandstrippedskinwasmetabolizedtoketoprofen(KP).theconcentrationofwhichinthereciiversolutionincreasedlinearlywithtime.Astothenudemouseskin.thesteady-statefluxofKPthroughwholethicknessskinwas2.5timesthatofKPEthroughthewhloethicknessskin,buttheKPandKPEremaininginthewholethicknessskinafterthefinishingofKPEpenetrationwas22.2timesincomperedwiththeKPremaininginthewholethicknessskinafterthefinshingofKPpenetration.TherateofformationofthesteadystateKPfromKPEthroughtdermiswassignificantlylowerthanthatofKPEthroughthewholethicknessskin.Inhemonkeyskin,therateofformationofthesteady-stateKPfromKPEthroughthewholethicknessskinwas0.7timesthatfromKPEthroughstrippedskin.TheKPandKPEremaininginthewholethicknessskinafterthefinishingofKPEpenetrationwas2.0timethatinthestrippedskinafterthefinishingofKPEpenetration.Therateoffornationofthesteady-stateKPfromKPEthroughdermiswaslowerthanthatfromKPEthroughthewholethicknessskinandthestrippedskin.theKPremainingindermisafterthefinsihingofKPEpenetrationwasalsosignificantlylowerthantheKPremaininginthewholethicknessskinandthestrippedskinafterthefinishingofKPEpenetration.Conclusion:KPestersareofbenefittoimporovethelocalactionofKP.andskinesterasemetabolismmainlydevelopsintheepidermis.

简介：目的了解福建汉族人群D2S44、D10S28、D4S163VNTR多态性，为亲权关系概率计算提供基因频率。方法采用美国Lifecodes公司提供的VNTR检测试剂盒，应用RFLP技术首次对福建省9个地市103名汉族无关个体进行D2S44、D10S28、D4S163VNTR多态性研究，并将所得基因频率与中国台湾、香港、新加坡等地区进行比较。结果福建汉族人群三位点VNTR呈高度多态性，其杂合率分别为88．6％、86．3％、90．6％，呈孟德尔经典遗传，分布符合Hardy-Weinberg平衡定律。结论福建、台湾、香港、新加坡华人互为比较，D2S44、D10S28位点基因频率没有显著性差别(P>0．500)。

简介：多多喝水夏季心烦、脾胃停滞，容易造成胃肠不消化、胀气、食欲不振等，从现在起应避免肥腻食物，改由新鲜、清淡饮食取代。乳制食物、过多盐分的食物和油炸食物，或是进补的羊肉炉、麻油鸡、烧酒鸡等，不适合在夏天食用。对老人及小孩，不易消化的糯米也要适可而止。

简介：宝宝饮食太重要，科学喂养要记牢。”哪些食物该吃，哪些食物不宜多吃，对宝宝的健康成长十分重要。

简介：Symptomatichepato-diaphragmaticinterpositionofabowellooporChilaiditi'ssyndromeisapeculiaranatomicalconditionmostoftenfoundbychance.Itsdescribedsymptomsrangefromintermittent,mildabdominalpainanddyspepsiatoacuteintestinalobstruction.Wereportacaseofhepato-diaphragmaticmigrationofthehepaticflexureofthecolonassociatedtoanunusual,heretoforeunreported,angina-likepainexclusivelyevokedbytheleftlateraldecubitus.Tomaximizethechanceofobservinganatomicalchangesindifferentpostures,computedtomographyofthechestandabdomenwasperformedafterairinsufflationintothecolon.Whilefrankherniationintothechestwasexcluded,thescanshowedthatthehepaticflexure-withtheinterpositionofthediaphragm-cameincontactwiththerightsideoftheheartintheleftlateral,butnotinthesupine,decubitus.Thisfindingwasreproducedbyechocardiographywhichalsoshowedvirtuallyunalteredhemodynamicsafterthechangeofposture.ECG,leftandrightventricularglobalandregionalfunctionaswellascardiacinjurymarkersalsoremainedunchangedduringthemaneuver,indicatingthatthepainevokedbythelatterwasunlikelyduetomyocardialischemia.ThiscasesuggeststhatChilaiditi'ssyndromeshouldbeincludedamongthepossible,althoughrare,causesofunexplainedangina-likesymptoms.

简介：In2001and2002,publicationoftheresultsofthreelargerandomizedcontrolledtriais(RCTs)changedourunderstandingoftherisksandbenefitsofhormonereplacementtherapy(HRT),leadingtonewguidancefromnationaladvisorybodiesonitsuse.Manyclinicaliyrelevantquestionsremainunanswered,butparadoxicallythereultsofrecenttrialsmayhavemadeitmoredifficulttodesignthestudiesnecessarytoanswerthesequestions.TheUKWISDOMtrial(oestrogen-progestogenvsplaceboinhealthywomen),forexample,hasbeendiscontinued.

简介：Overthedecade,ChineseBiomedicalEngineeringhasmaderemarkleprogressandaccumulatedmuchexperience.Animportantproblemfacingusishowtotaketheroadaheadofus.Firstofall,weshouldchangeourconventionalconceptandheadforthenewroad.Aboutthreeyearsago,wemadeaspecialreviewontheconnotationandchar-acteristicsofbiomedicalengineeringandpointedoutthatBiomedicalEngineeringwas

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简介：Reiter'ssyndromeisasecondarydiseaseofurethrainfection.Itconsistsofurethritis,nonsuppurativearthritis,conjunctivitisandcutaneousmucosalesions.YoungmalesaremorelikelytogetReiter'ssyndromethanfemales.Thusfar,therearenoreportsofwomeninChinawithReiter'sSyndrome.ThisreportdocumentstwofemaleswithReiter'sSyndrome.

简介：波士顿科学国际有限公司是一家全球性的医疗技术产品研发、生产、营销公司，现有17，500名雇员，2005年的销售收入为63亿美金。在过去的二十五年中，公司为广泛的医疗技术领域提供了具有深度和广度的众多创新产品，从而推动了微创介入产品的实践和发展。通过提供传统外科手术的替代产品，波士顿科学公司致力于帮助医生和其它医疗行业工作者改善病人的生命质量。

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简介：ThehistogensisofextramammaryPaget’sdiseasehasnotbeensolvedandremainedcontroversial.EightcasesofextramammaryPaget’sdiseaseofgeni-tocruralregionwereinvestigatedbyalcianblueandPASstainandimmunoreactionofanti-CEAandanti-keratin.Itwasfoundthatthepatternandintensityofalcianblue,PASstainingwereidenticalforPagetcellsandsecretorycellsofapocrinesweatgland;andCEAimmunoreactivitywasuniformlyobservedinbothPagetcellsandeccrinesweatgland.Thekeratinimmunoreactionwaspositiveinkeratinocytes,apocrineandeccrinesweatgland,whereasPagetcellswerenegative.TheseresultssuggestedthatPagetcellsofextramammaryPaget’sdiseasecouldbederivedfrommultipotentialepidermalgermcells.