简介:摘要目的了解湖南省嘉禾县伤寒+副伤寒变化趋势及流行病学特征。方法收集嘉禾县1990-2009年甲乙类传染病疫情报告资料进行整理建立数据库,采用描述性流行病学分析方法,并运用率的x检验进行统计分析。结果嘉禾县1990-2009年伤寒+副伤寒发病率呈阶段性波浪式变化,总体逐年下降趋势流行,年平均发病率22.44/10万,年发病率在1.33/10万-142.68/10万之间波动;发病人群以农民和学生为主,青壮年多发,四季均有发病,主要分布在2、6、7、8、9月,高发地区主要集中在人口流动频繁的乡镇。结论伤寒+副伤寒发病主要与环境卫生、生活习惯直接相关,大力开展爱国卫生运动,加强健康教育,改变不良的饮食饮水卫生习惯等综合措施是控制伤寒副伤寒疫情的有效途径。
简介:·Descemet’smembranedetachment(DMD)canbeapotentiallyseriouscomplicationofintraocularsurgeryoroculartrauma.Thecauseisnotveryclear.WearetryingtoremindanawarenessofthespectrumofDMDresultingfromtrabeculectomybypresentingacaseofextensiveDMDaftertrabeculectomywhichwassuccessfullyrepaired.
简介:<正>DearSir,IamDr.HuijaeLee,fromtheSeoulIreEyeClinic,Seoul,Korea.Iwritetopresentacasereportofesotropiaafterocclusiontherapy.Amblyopiacanbecausedby
简介:AIM:Toevaluatechangesintheanteriorchamberdepth(ACD),crystallinelensthickness(LT)anditsrefractivepowerafterlaserinsitukeratomileusis(LASIK).·METHODS:Inallcases,thepreoperativeandpostoperativecentralACDwhichweremeasuredwithPentacam,Orbscan,IOL-MasterandA-scanultrasonography,centralcornealtruenetpowerwhichwasmeasuredwiththePentacam,OrbscanandIOL-Master,axiallength(AL)whichwasmeasuredwithIOL-MasterandLTwhichwasmeasuredwiththeA-scanultrasonographywerecomparedusingthepairedsamplettest.OcularrefractiveerrorsandlensrefractivepoweratcornealplanewerecalculatedandtheircorrelationswerealsoevaluatedbeforeandafterLASIK.RESULTS:At1weekafterLASIK,LTandcrystallinelensrefractivepoweratcornealplane(Dlens)whichwereassociatedwiththeIOL-MasterandPentacamincreasedsignificantly(P≤0.005),ACDdecreasedsignificantly(P≤0.001),butnosignificantincreasewasobservedintheDlenswhichwasassociatedwiththeOrbscan(P=0.261).SignificantcorrelationsbetweenthechangesintheocularrefractiveerrorsandDlenswhichwereassociatedwiththePentacamwereobservedat1weekand6monthsafterLASIK(P=0.028;P=0.001).CONCLUSION:LTincreasedsignificantlyafterLASIK,andthismightpartiallyleadtoACDdecrease,Dlensincreaseandasmallquantityofmyopicregression.
简介:AIM:ToevaluatetheeffectofCollagencross-linkingonthepreventionofmeltinginrabbitcorneasafteralkaliburn.·METHODS:TwentyNewZealandwhiterabbitswererandomlydividedintomodelcontrolgroupandcollagencross-linkingtreatmentgroup.Thesecondgroupofrabbitsreceivedcollagencrosslinkedtreatment.Bothgroupswereappliedwithantibioticeyedropstopreventinfection.Thecorneaswereevaluatedformelting,opacity,pathologicalandimmunohistochemistry,recordthechangeswhen28daysaftertheanimalswerekilled.·RESULTS:Inthecontrolgroup,6outof8rabbitsshowedcornealmeltingafterinjury(14±4)days,whiletwocornealperforated.Incollagencross-linkingtreatmentgroup,onerabbitshowedcornealmeltingafterinjury23days,withoutcornealperforation;cornealdissolutionratebetweenthetwogroupswassignificantlydifferent(P<0.05).Pathologicalexaminationsuggestedthatinthetreatmentgroup,mildcornealedema,milddamagetocollagenfibers,inflammatorycellinfiltrationwassignificantlylessthanthecontrolgroup.Immunohistochemistryshowedthatcornealcollagenfibersarrangedinneatrowsinthecontrolgroup.·CONCLUSION:Collagencross-linkingtreatmentnotonlycanpreventanddelaythecornealmeltingafteralkaliburn,butalsocanreducethedestructionofcornealcollagenfibersandinfiltrationofinflammatorycellsinthecornealtissue.
简介:AIM:Toinvestigatetheantifibroticeffectofthefreeze-driedbilayeredfibrin-bindingamnioticmembraneasadrugdeliverysystemonglaucomasurgeryinrabbitmodel.Theaimofthisstudywastoprepareanovellocaldeliverysystemforthesustainedandcontrollablereleaseof5-Fu.METHODS:Twenty-fourJapanesewhiterabbitswererandomizedintothreegroups:theexperimentalgroup(oculartrabeculectomyincombinationwith5-Fuloadedfreeze-driedbilayeredfibrin-bindingamnioticmembranetransplantation),thecontrolgroup(oculartrabeculectomyincombinationwith5-Fu)andtheblankgroup(singletrabeculectomy).HEstaining,massionstainingandimmunohistochemistryforα-SMAwereperformedondays7,14,21and30followingsurgery.Theconcentrationof5-Fuinrabbitaqueoushumorwasexaminedbyhighperformanceliquidchromatography(HPLC)3daysafterthesurgery.RESULTS:Statisticaldifferenceswerenotedinintraocularpressureamonggroupsonday7,14,21and30followingsurgery.Histologyfurtherdemonstratedthattrabeculectomyincombinationwithfreeze-driedbilayeredfibrin-bindingamnioticmembraneyieldedwellwoundhealingandnoscarformationandwasbeneficialforlongtermeffect.CONCLUSION:HPLCshowedagoodslow-releaseeffectwithfreeze-driedbilayeredfibrin-bindingamnioticmembrane.
简介:摘要目的了解抚顺市暗娼人群梅毒流行状况,为制定防治措施提供科学参考依据。方法2009年-2011年对抚顺市辖区内的不同档次的洗浴中心、桑拿、足疗房、KTV等场所的暗娼人群进行问卷调查,并对该人群进行梅毒血清学检测。结果2009年-2011年暗娼梅毒感染率依次为5.49%,3.50%,3.00%。每次安全套使用率依次是10.00%,44.25%,70.25%,最后一次安全套的使用率依次是55.86%,76.75%,99.50%。是否接受过干预服务的暗娼人群间梅毒发病存在统计学差异(X2=3.28,P<0.1)。2009年-2011年艾滋病知识知晓率分别为82.04%,92.5%,98%,不同文化程度暗娼人群间知晓率无统计学差异(X2=3.07,P=0.38)。结论暗娼人群干预工作需进一步提高,以控制梅毒和艾滋病传播。
简介:摘要目的掌握我县麻疹发病特点,更好地指导我县消除麻疹工作。方法资料源于国家传染病疫情信息网华县疫情信息报告网,对我县2005年-2011年的麻疹病例进行了认真核对分析。结果2005年-2011年共发病39例,无死亡病例,2006年发生1次麻疹爆发流行。报告发病率2005年发病率1.92∕10万,2006年发病率为3.00∕10万,2007年发病率,2008年发病率0.54/10万2009年发病率0.54/10万,2010年发病率2.42∕10万、2011年发病率1.24/10万。结论我县麻疹发病率呈下降趋势,但流动儿童和麻疹疫苗下限月令儿童发病呈上升趋势。消除麻疹工作刻不容缓。