ENDOCOCHLEAR POTENTIAL AND POTASSIUM CONCENTRATION RECORDING IN MINIPIG COCHLEA

(整期优先)网络出版时间:2012-02-12
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ObjectiveTorecordtheendocochlearpotential(EP)andcalculatepotassiumconcentration[K+]inMinipigcochleae.MethodsWeusedmulti-barreledelectrodestomeasuretheEPandthepotential,[K+].EPandpotassiumelectroderecordingweremadein9cochleaefrom5minipigstogetnormalEPvalues.ResultsTheaverageEPvalueinthecochleafromtheminipigswas77.3±14mV.Theaverage[K+]fortheminipigswas147.1±13mM.ConclusionsTheEPandpotential,[K+]inminipigsarelowerthaninthehumanandrodents.ThismaybethereasonwhyporcineABRthresholdsareslightlyhigherthanhumansandrodents.