简介:摘要目的对比瑞巴派特和埃索美拉唑防治非甾体抗炎药胃病的临床里疗效。方法对我院2017年5月至2018年5月共138例非甾体抗炎药胃病患者进行研究,随机分为观察组和对照组各69例。对照组采用埃索美拉唑治疗,观察组采用瑞巴派特治疗,对比两组临床疗效。结果观察组总有效率高于对照组(X2=8.118,P=0.004)。治疗前两组各项临床症状评分无明显差异差异,P>0.05;治疗后两组各项临床症状评分均有所下降,且组间差异明显,P<0.05。结论瑞巴派特和埃索美拉唑防治非甾体抗炎药胃病均具有良好的疗效,相比之下瑞巴派效果更加明显,可作为临床一线治疗方案,值得推广应用。
简介:摘要目的研究拉贝洛尔联合甲基多巴治疗妊娠期高血压疾病患者的临床效果。方法以92例妊娠期高血压患者的入院时间为标准将其分为两组,分别给予硫酸镁治疗(对照组46例)与拉贝洛尔联合甲基多巴治疗(观察组46例),对比两组患者治疗效果差异。结果观察组患者治疗后平均动脉压、24h尿蛋白两项指标与对照组患者相比均明显下降且具有统计学意义(P<0.05)。观察组患者治疗期间不良反应发生率(8.7%)与对照组患者(23.9%)相比明显降低且具有统计学意义(P<0.05)。结论拉贝洛尔联合甲基多巴治疗妊娠期高血压患者效果显著,能有效改善患者血压指标且安全性好,值得临床推广。
简介: [摘要 ]目的 探讨沙库巴曲缬沙坦治疗慢性心功能不全的临床效果。方法 选取我院 2017年 6~ 10月收治的 30例慢性心功能不全患者作为研究对象,所有患者在常规治疗基础上加用沙库巴曲缬沙坦治疗,标准化连续治疗 3个月,观察患者治疗的总有效率,比较患者治疗前后的心功能指标、血浆 N末端脑钠肽( NT-proBNP)水平、生活质量。结果 治疗后,显效 15例,有效 13例,无效 2例,总有效率为 93.33%。治疗后,患者的 LVEF、 FS及 KCCQ量表评分均显著高于治疗前, NT-proBNP水平显著低于治疗前,差异有统计学意义( P<0.01)。不良反应发生率为 10.00%。结论 沙库巴曲缬沙坦治疗慢性心功能不全可明显改善患者的心功能,降低其 NT-proBNP水平,安全可靠,可显著提高其生活质量,值得临床推广。 [关键词 ]沙库巴曲缬沙坦;慢性心功能不全;心功能;生活质量 [abstract] Objective To investigate the clinical effect of sakubatroxol and Valsartan in the treatment of chronic cardiac insufficiency. Methods Thirty patients with chronic cardiac insufficiency admitted to our hospital from June to October 2017 were selected as the research objects. All patients were treated with Sakubatroxatan on the basis of routine treatment. The standardized continuous treatment lasted for three months. The total effective rate of the patients was observed. The cardiac function indexes and plasma N-terminal brain of the patients before and after treatment were compared. Natriuretic peptide (NT-proBNP) level and quality of life. Results After treatment, 15 cases were markedly effective, 13 cases were effective and 2 cases were ineffective. The total effective rate was 93.33%. After treatment, the scores of LVEF, FS and KCCQ were significantly higher than those before treatment, and the levels of NT-proBNP were significantly lower than those before treatment (P < 0.01). The incidence of adverse reactions was 10.00%. ConclusionSakubattral and valsartan can significantly improve cardiac function and reduce NT-proBNP level in patients with chronic cardiac insufficiency. It is safe and reliable, and can significantly improve their quality of life. It is worthy of clinical promotion.
简介:【摘要】目的:探讨在慢性心力衰竭患者治疗中采用沙库巴曲缬沙坦钠的效果。方法:研究开始纳入病例的时间定在2022年4月,截止到2023年4月,一共纳入80例,均在我院确诊为慢性心力衰竭,随机分组,对照组(n=40,缬沙坦胶囊治疗)与研究组(n=40,沙库巴曲缬沙坦钠治疗),对比治疗有效率、心功能相关指标、NT-proBNP及运动耐量(6分钟步行距离)。结果:研究组在疗效方面较对照组高,P<0.05;研究组心功能指标中LVEDD以及LVESD水平均较对照组低,研究组LVEF较对照组高,P<0.05;研究组在NT-proBNP水平的比较重较对照组低,6分钟步行距离较对照组多,P<0.05。结论:在治疗慢性心力衰竭患者时与缬沙坦胶囊相比,服用沙库巴曲缬沙坦钠能够提高疗效,改善患者的心功能,提高运动耐量,促使病情好转。