简介:AIM:Toevaluatewhetherglaucomatousvisualfielddefectparticularlythepatternstandarddeviation(PSD)ofHumphreyvisualfieldcouldbeassociatedwithvisualevokedpotential(VEP)parametersofpatientshavingprimaryopenangleglaucoma(POAG).METHODS:VisualfieldbyHumphreyperimetryandsimultaneousrecordingsofpatternreversalvisualevokedpotential(PRVEP)wereassessedin100patientswithPOAG.ThestimulusconfigurationforVEPrecordingsconsistedofthetransientpatternreversalmethodinwhichablackandwhitecheckerboardpatternwasgenerated(fullfield)anddisplayedonVEPmonitor(colour14')byanelectronicpatternregeneratorinbuiltinanevokedpotentialrecorder(RMSEMGEPMARKII).RESULTS:Theresultsofourstudyindicatethatthereisahighlysignificant(P<0.001)negativecorrelationofP100amplitudeandastatisticallysignificant(P<0.05)positivecorrelationofN70latency,P100latencyandN155latencywiththePSDofHumphreyvisualfieldinthesubjectsofPOAGinvariousagegroupsasevaluatedbyStudent’st-test.CONCLUSION:ProlongationofVEPlatenciesweremirroredbyacorrespondingincreaseofPSDvalues.Conversely,asPSDincreasesthemagnitudeofVEPexcursionswerefoundtobediminished.