简介:Thisstudyaimsattheeffectsofanintakeoflowmolecularweightcornpeptides(LMCPs)preparedfromzeinonalcoholmetablisminrats.LMCPs(1.0g/kgbodyweight)in15%ethanol(10mL/kgbodyweight)weregiventoWisterratsbyintragastricgavage.Theassayofbloodethanolwasconductedbyusingtheenzyme-basedassaykit.Theaminoacidanalysiswasmadewithanaminoacidanalyzer.ThedataoftheanimalexperimentsshowedthatLMCPscouldacceleratethemetabolismofalcoholinrats.Inthecontrolgroup,thebloodethanolconcentrationreachedthemaximumlevelof(827.0±77.3)mg/Lafterethanolloadingfor30min,thengraduallydecreased.Incontrast,thebloodethanolconcentrationonlyreached(527.25±47.0)mg/Lafter30mininthegroupofLMCPstaken.TheseresultsindicatethatLMCPscoulddecreaseethanolconcentrationinbloodrapidly.
简介:Introduction:Congestiveheartfailure(CHF)accountsforover$32billioninhealthcarecostsperyearandisattheepicenterofhealthcarereform.CHFremainsamajorcauseofhospitalizations.Itisknownandhasbeenreportedthatmisseddiagnosisofandmissedopportunitiestotreatheartfailureareassociatedwithhighermortalityandmorbidity.CHFdiseasemanagementprogramshaveemergedasapotentialsolutiontotheCHFepidemic.TheparadoxremainsthatCHFdiseasemanagementprogramsstillclusterintertiaryhospitalsystems.Theimpactofheartfailurespecialistsandspecialtyteamsincommunityhealthsystemsislesswellunderstood.CurrentlytherearenotenoughCHF-trainedteamsinthecommunitysettingtoaddressthisunmethealthneed.Methods:WeexploredtheimpactofCHFclinicsinacommunity-basedhospitalsystemonreadmissionrates,mortality,andsymptomaticrelief.Atotalof384patientswereenrolledintheclinicbetween2012and2015.Datacollectedincludedage,sex,typeofheartfailure,NewYorkHeartAssociationclass,ejectionfraction,serumcreatinineandbrainnatriureticpeptidevalues,andreadmissionandmortalityrateswithin30days,3months,6months,and1year.WealsocomparedreadmissionratesbetweenpatientswhowerefollowedupintheCHFclinicversusthosewhowerenotseenintheCHFclinic.Results:AstatisticallysignificantdifferencewasdemonstratedinreadmissionratesbetweenpatientswhowerefollowedupintheCHFclinicversusthosewhodidnotvisittheCHFclinicforupto1yearoffollow-up.Conclusion:CHFcommunityhospitalclinicsthatusearapidandfrequentfollow-upformatwithCHF-trainedteamseffectivelyreducerehospitalizationratesupto1year.