简介:摘要:TDCS/CTC系统即列车调度指挥系统和调度集中系统是铁路运输中重要的行车指挥系统,网络安全对于系统的稳定运行起着至关重要的作用。同时新版《信息安全技术网络安全等级保护基本要求》已正式施行,TDCS/CTC系统属于等级保护第四级,因此对网络安全技术提出了更高的要求。本文对TDCS/CTC系统网络安全技术进行了简单分析,同时结合新版等级保护要求对系统存在的不足提出了建议。
简介:摘要目的评价老年精神分裂症患者给予盐酸齐拉西酮联合rTMS治疗的效果。方法选择2017年8月-2018年8月在我院接受治疗的老年精神分裂症患者50例,随机分为两组,单一组患者仅给予盐酸齐拉西酮治疗,联合组在单一组基础上给予rTMS治疗,评价两组患者治疗效果,对比两组血清NGF水平。结果在治疗效果方面,单一组和联合组PANSS量表评分在25%以上患者分别占76.0%、96.0%,联合组PANSS量表评分显著高于单一组(P<0.05);在血清NGF水平方面,两组患者治疗前血清NGF水平对比不显著(P>0.05),治疗后,单一组和联合组血清NGF水平均有一定的升高,联合组血清NGF水平显著高于单一组(P<0.05)。结论老年精神分裂症患者给予盐酸齐拉西酮联合rTMS治疗,可改善患者PANSS评分和血清NGF水平,值得推广应用。
简介:摘要ObjectiveTo determine the mechanisms on cognitive improvement with repetitive transcranial magnetic stimulation (rTMS) over the left dorsolateral prefrontal cortex(L-DLPFC) in subacute stroke patients.MethodsTwenty-eight first-ever stroke patients with cognitive impairment were recruited. All subjects were randomly assigned to real or sham stimulation group and completed 10 sessions of rTMS for 2 weeks. 10 Hz of navigation rTMS were applied (5 s stimulation and 25 s resting, total 1500 pulses) on the L-DLPFC at 80% of resting motor threshold (rMT). At the time of baseline, 1 month and 3 months after stroke onset, all subjects received the Korean-mini mental state examination (K-MMSE), Korean-Montreal Cognitive Assessment (K-MOCA), Upper Fugl-Meyer Assessment (U-FMA), Korean-Modified Bathel Index (K-MBI), European Quality of life 5 Dimension (EQ-5D), Korean-Geriatric Depression Scale (K-GDS). In addition, the continuous performance test (CPT), vascular cognitive impairment harmonization standards (VCIHS), motor evoked potentials (MEP), event-related potentials (ERPs), resting state functional magnetic resonance imaging (RS fMRI) and diffusion tensor imaging (DTI) were completed at baseline and 3 months after stroke onset.ResultsAfter the intervention period, the real stimulation group improved significantly in the K-MMSE, K-MOCA, K-MBI and K-GDS compared with sham stimulation group. And these effects lasted after three months in MOCA. There was no significant time × group effect among the U-FMA, EQ-5D, and CPT. Among the VCIHS parameters, Z-scores of executive and memory function showed higher delta value between baseline and 3months timepoints in rTMS group. The MEP showed higher TIME × GROUP interaction in the intracortical inhibition value on right hand. It suggests that there is beneficial effect on premotor cortical excitability of rTMS. The change of P300 amplitude on F3 and C3 was more increased in real stimulation group significantly only in the auditry Oddball paradigm. The RS fMRI analysis results showed more increased functional connectivity of Cingulate Gyrus, Supramarginal Gyrus, Cerebelum Crus2, Precentral gyrus, Middle temporal gyrus and Inferial temporal gyrus after stimulation compared with the sham group. Brain activation in the cingulum showed a tendency that after 3 months, fractional anisotropy (FA) and fiber number (FN) in real group were larger than sham group, however there was no significant effect. The relationship between the change of K-MOCA and fractional anisotropy of the cingulum was found positive correlation in all subjects.ConclusionsThese results suggest that high frequency rTMS on the L-DLPFC improves cognitive function and functional network activity in subacute stroke. The rTMS seems to be a recommendable treatment in stroke patients with cognitive impairment.
简介:摘要目的分析探讨米氮平联合rTMS治疗伴睡眠障碍的焦虑症临床效果。方法从2017年11月至2018年5月期间在我院结束治疗的伴睡眠障碍的焦虑症患者中随机挑选62例作为本次研究的对象,根据治疗方法分为两组对照组(31例)和观察组(31例),对照组给予米氮平治疗,观察组给予米氮平联合rTMS治疗,观察两组患者的治疗效果。结果相比对照组,观察组患者治疗后各项相关睡眠数据均优于对照组,组间差异显著,P<0.05,存在统计学意义。观察组和对照组患者的治疗有效率分别为90.32%(28/31)、77.41%(24/31),相比较对照组,观察组患者的治疗效果明显更好,组间差异显著(P<0.05)。结论相比较单一治疗方法,米氮平与rTMS联合治疗伴睡眠障碍的焦虑症患者的效果更明显,能够有效的改善患者的睡眠质量,调节患者的焦虑情绪,有助于提高患者的身体健康。
简介:摘要:如今,在铁路行车指挥中已经采用了TDCS/CTC系统的行车指挥系统。这种TDCS/CTC系统是由国铁集团、各铁路局集团公司TDCS中心局域网及车站基层网组成,是一个覆盖全路的现代化铁路运输监视和指挥系统。但是,TDCS/CTC系统发生网络故障较多,故障种类也繁杂,如果把常见的典型故障进行归类总结,对迅速准确的查找故障根源、压缩故障处理延时很有益处。下面从站内网络故障和站间网络故障两个方面来分析TDCS/CTC系统网络故障,简述诊断及排除方法。
简介:摘要:目的 分析重复经颅磁刺激(rTMS)在脑梗塞运动功能康复中的作用。方法 2021年10月~2022年12月,我院收治脑梗塞患者82例为研究观察对象,依据随机数字表法分2组,对照组(纳入常规功能训练患者41例)、观察组(纳入常规功能训练+rTMS干预患者41例),观察两组运动功能、生活能力、家属满意度情况。结果 观察组与对照组相比干预后肢体功能(FMA)、生活能力(Barthel指数)评分更高,组别差异显著(P<0.05);观察组同对照组相比干预后家属满意度更高,组别差异显著(P<0.05)。结论 脑梗塞患者采用rTMS干预可以加速患者运动功能康复,改善患者生活能力,提高患者家属满意度。