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273 个结果
  • 简介:目的探讨并总结小切口白内障囊外摘除联合人工晶状体植入术治疗晶状体溶解青光眼的临床疗效。方法回顾分析2011年3月至2016年5月间在我科确诊并行小切口白内障囊外摘除联合人工晶状体植入术的30例30眼晶状体溶解青光眼,观察并记录其视力、眼压及并发症等变化情况。结果30例患者手术均顺利进行,术中未出现任何并发症,术后3个月随访时视力恢复良好,有6眼视力在0.1-0.5,占20.0%,24眼视力在0.6-0.8,占80.0%,矫正视力在1.0及其以上的有6眼,占20.0%;所有患者术后随访时眼压均在正常范围;术后均无严重影响眼压及视力的并发症出现。结论小切口白内障囊外摘除联合人工晶状体植入术治疗晶状体溶解青光眼具有良好的临床效果,值得在基层医院推广。

  • 标签: 小切口 白内障囊外摘除术 人工晶状体 晶状体溶解性青光眼
  • 简介:医疗系统的前景是什么?作为眼科医疗工作者,我们不仅要治疗眼睛,我们更要治疗患者。同样,眼科医疗并非在真空中作业,而是从属于更宽泛的医疗保健系统。当我们的工作需要如此之多的人力之时,很可能让人忘记工作的大背景是什么。然而,

  • 标签: 眼科医疗系统 服务 人力资源 信息
  • 简介:目的观察球后注射山莨菪碱联合高压氧治疗非动脉炎前部缺血性视神经病变的疗效。方法选取2015年6月-2016年6月我院收治的60例非动脉炎前部缺血性视神经病变患者,随机分为2组:治疗组和对照组,2组均给予皮质激素、血管扩张剂、营养神经类药物等治疗。治疗组在此基础上给予山莨菪碱球后注射联合高压氧,15天后除了停止球后注射山莨菪碱,其余治疗不变,30天后比较2组治疗前后视力、视野的改变。结果视力治疗组治愈13眼,显效4眼,有效10眼,无效3眼。对照组治愈6眼,显效12眼,有效8眼,无效4眼。两组对比经ridit分析Z=-3.074,P=0.002。视野治疗组治愈15眼,显效9眼,有效3眼,无效3眼。对照组治愈3眼,显效8眼,有效14眼,无效5眼,两组经ridit分析Z=-3.504,P=0.000。结论球后注射山莨菪碱联合高压氧治疗缺血性视神经病变疗效较好。

  • 标签: 山莨菪碱 高压氧 非动脉炎性前部缺血性视神经病变
  • 简介:目的:探讨糖尿病患者黄斑中心凹下脉络膜厚度(SFCT)与脉络膜血流动力学指数及糖化血红蛋白之间的关系。方法:选择在我院眼科及内分泌科住院治疗的2型糖尿病患者78例156眼作为研究对象。其中男39例,女39例,平均(59.8±6.2)岁。根据ETDRS糖尿病视网膜病变分级方法,将患者分为无视网膜病变组、轻中度NPDR组、重度NPDR组、PDR组。采用EDI-OCT与超声多普勒对四组患者进行脉络膜厚度测量与脉络膜血流动力学指数测量。并记录所有患者的血糖化血红蛋白含量。采用多元线性回归分析SFCT与血流动力学指数与糖化血红蛋白的相关。结果:NDR患者组舒张末期血流速度(EDV)明显高于其它患者组,SFCT较其它各组偏薄,差异有统计学意义。四组患者收缩期峰值血流速度(PSV)无统计学差异;重度NPDR组血管阻力指数(RI)高于NDR组及轻中度NPDR组;PDR组RI进一步增高,差异有统计学意义。SFCT与糖化血红蛋白有显著正相关(b=0.540,P〈0.001);SFCT与DR分级(P=0.341)、PSV(P=0.770)、EDV(P=0.131)及RI(P=0.084)无显著相关。结论:糖尿病患者SFCT与血流动力学各指数无相关。糖化血红蛋白是糖尿病患者SFCT的影响因素之一。

  • 标签: 糖尿病 糖尿病脉络膜病变 体层摄影术 光学相干 彩色多普勒显像
  • 简介:AIM:ToevaluatetheeffectofCollagencross-linkingonthepreventionofmeltinginrabbitcorneasafteralkaliburn.·METHODS:TwentyNewZealandwhiterabbitswererandomlydividedintomodelcontrolgroupandcollagencross-linkingtreatmentgroup.Thesecondgroupofrabbitsreceivedcollagencrosslinkedtreatment.Bothgroupswereappliedwithantibioticeyedropstopreventinfection.Thecorneaswereevaluatedformelting,opacity,pathologicalandimmunohistochemistry,recordthechangeswhen28daysaftertheanimalswerekilled.·RESULTS:Inthecontrolgroup,6outof8rabbitsshowedcornealmeltingafterinjury(14±4)days,whiletwocornealperforated.Incollagencross-linkingtreatmentgroup,onerabbitshowedcornealmeltingafterinjury23days,withoutcornealperforation;cornealdissolutionratebetweenthetwogroupswassignificantlydifferent(P<0.05).Pathologicalexaminationsuggestedthatinthetreatmentgroup,mildcornealedema,milddamagetocollagenfibers,inflammatorycellinfiltrationwassignificantlylessthanthecontrolgroup.Immunohistochemistryshowedthatcornealcollagenfibersarrangedinneatrowsinthecontrolgroup.·CONCLUSION:Collagencross-linkingtreatmentnotonlycanpreventanddelaythecornealmeltingafteralkaliburn,butalsocanreducethedestructionofcornealcollagenfibersandinfiltrationofinflammatorycellsinthecornealtissue.

  • 标签: COLLAGEN cross-linking CORNEAL ALKALI BURN CORNEAL
  • 简介:目的了解上海市普陀区4-7岁儿童阻塞睡眠呼吸暂停低通气综合征(OSAHS)的患病率及相关危险因素,探讨问卷调查在筛选疑似病例中的价值。方法以班级为单位采取整群抽样的方法从上海市普陀区幼儿园及小学一年级中抽取4-7岁学生6000例,由学生家长填写问卷,再从中随机抽取无打鼾或轻微打鼾者10例,有频繁打鼾症状的儿童42例,行多导睡眠监测。结果实际调查人数5040(应答率为84.0%),有效问卷4045份(有效率为80.23%),按睡眠呼吸暂停低通气指数(AHI)≥5次/h、最低血氧饱和度(LSaO2)≤0.94为标准,根据多导睡眠监测结果,估算上海市4-7岁儿童OSAHS的患病率为3.91%。AHI与腺样体肥大相关较强(偏相关系数为0.373);将问卷中打鼾、憋气、反复翻身、夜尿发生率等选项分配一个0-4分的数值,调查问卷得分与AHI呈正相关(r=0.518)。问卷中打鼾、张口呼吸选项的敏感度较高(95%、87%),特异性一般(67%、79%);憋气、憋醒选项敏感度一般(66%、29%),特异度较高(93%、100%);夜尿及反复翻身选项无统计学意义(P〉0.05)。结论上海市普陀区4-7岁儿童OSAHS的患病率估计为3.91%,腺样体肥大为患病主要原因;设计合理的调查问卷可用于初步筛选儿童OSAHS疑似病例,对早期诊断和治疗具有重要参考价值。

  • 标签: 睡眠呼吸暂停低通气 阻塞性 流行病学 儿童
  • 简介:目的比较急性中心性浆液脉络膜视网膜病变(CSC)的患侧与对侧眼视网膜频域相干光断层扫描(OCT)的图像特征。方法应用频域OCT对30例(60眼)单眼发病急性CSC患者患侧和对侧眼的黄斑部视网膜显微结构进行检测,比较患侧组与对侧组黄斑中心凹外核层厚度、光感受器层(IS/OS层)、视网膜色素上皮(RPE)形态差异。结果所有30例患者患侧眼均有不同程度黄斑部视网膜浆液脱离,对侧眼中有4眼(13.3%)存在轻度视网膜浆液脱离;患侧组黄斑中心凹外核层厚度均值为(95.32±24.87)μm,对侧组为(98.80±14.36)μm,两组差异无统计学意义(t=1.627,P=0.110)。患侧组中IS/OS层厚度均匀一致者12眼(40.0%),对侧组20眼(66.7%);患侧组IS/OS层厚度均匀一致伴内外节缺损、不均、凸起增厚者共18眼(60.O%),对侧组共10眼(33.3%),差异有统计学意义(X2=4.28,P=0.038)。患侧组中出现RPE异常者有24眼(80.0%),对侧组中有8眼(26.7%),差异有统计学意义(x。=17.143,P=0.000)。结论频域OCT能清晰显示急性CSC患者的细微病理结构改变,单眼发病CSC患者中一部分对侧眼存在IS/OS层和RPE异常,但是其发生率较患侧眼低。(中国眼耳鼻喉科杂志,2013,13:165—167)

  • 标签: 相干光断层扫描 脉络膜视网膜病变 急性 浆液性 对侧眼
  • 简介:·AIM:Toexploretheeffectofimmunizationwithcopolymer-1(COP-1)andretinalstemcells(RSCs)transplantationoninterferon-gamma(IFN-γ)levelsinaratexperimentalglaucomamodel.·METHODS:Anexperimentalglaucomawasinducedbyargonlaserphotocoagulationoftheepiscleralveinsandlimbalplexusintherighteyeofrats.Immediatelyfollowingglaucomainduction,ratswereimmunizedwithCOP-1.RSCswereculturedandtransplantedintravitreallyintotheeyesofglaucomamodelanimals1weekpost-lasertreatment.Sixexperimentalgroupswereused:COP-1/RSC,PBS/RSC,COP-1/PBS,PBS/PBS,glaucomamodelgroup,andanormalcontrolgroup.TheconcentrationofIFN-γinaqueoushumor(AH)andserumwasmeasuredbyenzyme-linkedimmunosorbentassay(ELISA)ineachofthesixgroups.Retinalganglioncell(RGC)survivalwasassessedbyquantifyingapoptosisusingHoechststaining.·RESULTS:ConcentrationsofIFN-γinAHandserumofratsthathadundergoneglaucomainductionwerehigherthanthoseofnon-inducedcontrolrats.TheconcentrationsofIFN-γinAHandserumoftheCOP-1/RSCstreatedgroupweredeterminedtobe2371.9ng/Land710.9ng/L,respectively,whichweresignificantlylowerthanthoseintheothertreatedgroups(P<0.05).Infact,IFN-γlevelsinthedualtreatedgroupwerereducedtobackgroundlevels.TheCOP-1/RSCgrouphadlowernumberofapoptoticRGCsthantheotherthreeexperimentalgroups(P<0.05).·CONCLUSION:ThereducedlevelsofIFN-γinAHandserumoftheCOP-1/RSCgroupmayberelatedtosynergisticeffectsbetweenRSCstransplantationandCOP-1immunemodulation.ItislikelythatthelowerlevelsofIFN-γpreventedRGCsglaucomatousapoptosis.·

  • 标签: GLAUCOMA INTERFERON-GAMMA RSC trans- PLANTATION COP-1
  • 简介:目的探讨自我管理项目在门诊青光眼患者中的应用及效果。方法将112例门诊青光眼患者随机分为56例对照组、56例干预组。对照组给予门诊常规药物治疗和常规健康教育指导;干预组在门诊常规药物治疗基础上,进行自我管理项目干预,比较两组病人的自我管理行为、自我效能水平和生活质量。结果干预后12周,干预组自我管理行为、自我效能水平和生活质量显著优于对照组(P〈0.05)。结论自我管理项目干预能提高青光眼患者自我管理行为、自我效能水平和生活质量。

  • 标签: 青光眼 自我管理 护理
  • 简介:·Thisisacasepresentationofaverybizarreopenglobetraumawithanteriorsegmentforeignbody-fishinghookstuckinthecorneaandiris.Complicationsduetothiskindofeyetraumamightbeveryhazardousandwithseriousimpactonvisualfunction.Wearerepresentingourapproachandexperienceofthreestepmanagementofthiskindofeyeinjury:first-extracttheforeignbody,closeandreconstructtheeyeball,second-fightinflammation,andthird-restorethevisualfunctionbycataractsurgery.·

  • 标签: eye TRAUMA ANTERIOR SEGMENT foreign body
  • 简介:目的探讨和总结“复明一号”眼科流动手术车在农村地区行白内障复明手术围手术期的管理方法。方法对“复明一号流动手术车”2012年在农村地区施行的5483例白内障手术联合人工晶体植入手术围手术期管理方法进行回顾分析和总结。结果在“复明一号”眼科流动手术车上施行的5483例白内障复明手术无一例严重的术中术后并发症发生。结论在眼科流动手术车上施行大规模白内障复明手术除严格遵守常规的围手术期护理方法外,还要结合农村地区的条件和在车上进行手术的特点制定实施围手术期管理方法,以减少手术并发症,使白内障复明手术安全高效。

  • 标签: “复明一号” 眼科流动手术车 围手术期管理 白内障
  • 简介:AIM:Topresenttheoutcomeofmodifiedgridlaserphotocoagulation(GLP)indiffusediabeticmacularedema(DDME)ineyeswithoutextrafovealand/orvitreofovealtraction.METHODS:InclusioncriteriafortheretrospectivestudywereDDMEeyesofpatientswithtypeⅡdiabetesmellitusthathad≥4monthsoffollow-upfollowingGLP.Onlyoneeyeperpatientwasanalyzed.Using3-Dspectral-domainopticalcoherencetomography(3-DSDOCT),eyesthathadeitherextrafovealorvitreofovealtraction,orhadbeenpreviouslytreatedbyanintravitrealmedication(s)wereexcluded.TreatedDDMEeyesweredividedinto4groups:A)'Classic'DDMEthatinvolvedthecentralmacula;B)edemadidnotinvolvethemacularcenter;C)eyesassociatedwithcentralepiretinalmembrane(ERM);D)DDMEthatwasassociatedwithmacularcapillarydropout≥2disc-diameter(DD).RESULTS:GLPoutcomein35DDMEeyesafter4-24(mean,13.1±6.9)monthswasasfollows:GroupA)18eyeswith'classic'DDME.Followingoneor2(mean,1.2)GLPtreatments,best-correctedvisualacuity(BCVA)improvedby1-2Snellenlinesin44.4%(8/18)ofeyes,andworsenedby1linein11.1%(2/18).Centralmacularthickness(CMT)improvedby7%-49%(mean,26.6%)in77.8%(14/18)ofeyes.CausesofCMTworsening(n=4)werecommonlyexplainable,predominantly(n=3)associatedwithemergenceofextrafovealtraction,5-9monthspost-GLP.GroupB)GLP(s)inDDMEthatdidnotinvolvethemacularcenter(n=6)resultedinimprovedBCVAby1-2linesin2eyes.However,thecentralmaculabecameinvolvedintheedemaprocessaftertheGLPin3(50%)eyes,associatedwithanemergenceofextrafovealtractioninoneoftheseeyes4monthsfollowingtheGLP.GroupC)GLPfailedinall5eyesassociatedwithcentralERM.GroupD)GLPwasofpartialbenefitin2of6treatedeyeswithmacularcapillarydropout≥2DD.CONCLUSION:EyeswithDDMEthatinvolvedthemacularcenterwerefoundtoachievefavourableoutcomesafterGLP(s)duringmid-termfollow-up,unlesscomplicatedpre-GLPorpost-GLPbyvltreoretinalinterfaceabnormalities,oftenextrafovealtra

  • 标签: extrafoveal TRACTION vitreofoveal TRACTION grid laser
  • 简介:AIM:Tocomparetheeffectoftopicallyadministeredandsubconjunctivallyinjectedbevacizumabonexperimentalcornealneovascularizationinratsfortwoweeksaftertreatment.METHODS:Twenty-eightSprague-Dawleyratsweredividedintofourgroupsof7animals.Eachcornealcenterofrighteyewascauterizedwithsilver/potassiumnitratefor8s.Aftercornealburning,bevacizumab(12.5mg/mL)wastopicallyadministeredthreetimesperday(TBgroup)fortwoweeksorsubconjunctivallyinjectedondays2and4aftercauterization(0.02mL;SBgroup).Asnegativecontrols,ratsreceived0.9%salinetopicallythreetimesperday(TSgroup)orsubconjunctivallyondays2and4(0.02mL;SSgroup).Digitalphotographsofthecorneaweretaken1and2weeksaftertreatmentandanalyzedtodeterminetheareaofcorneacoveredbyneovascularizationasthepercentageofcornealneovascularization.RESULTS:Oneweekaftertreatment,thepercentageofcornealneovascularizationwassignificantlylowerintheTBandSBgroupsthanintheTSandSSgroups(allP<0.05).Twoweeksaftertreatment,thepercentageofcornealneovascularizationwassignificantlylowerintheTBgroupthanintheTSgroup(P<0.05).Inallgroups,thepercentageofneovascularizationwasdecreasingastimepassed(allP<0.05)CONCLUSION:Topicallyadministeredbevacizumabhaslongerstandinganti-angiogeniceffectthansubconjunctivallyinjectedbevacizumabincornealneovascularizationfollowingchemicalinjuryinrats.

  • 标签: CORNEAL NEOVASCULARIZATION BEVACIZUMAB TOPICAL and SUBCONJUNCTIVAL