简介:根据国家科学基金(NSF)主任A。Bement,鈥楾ransformative研究是承受极端地改变我们一个重要存在科学概念的理解或导致一个新范例的创造或科学的地的一个合理机会的想法驾驶的鈥?研究。鈥?被它对当前的理解的挑战也描绘或它到新边疆鈥?纳米技术的小径是如此的边疆之一。它是在强烈与原子、分子的相互作用联系的分子的水平鈥?现象的新材料,设备和系统的创造影响宏观的材料性质与显著地改进了机械、光、化学、电的鈥?性质。在2002的以前的NSF主任丽塔·科尔韦尔声明了,鈥榥anoscale技术将有一个影响平等者到工业Revolution'。超群的技术包括纳米技术,微电子学,信息技术和生物工学以及创新、支持的机械、民用的基础结构系统和材料。这些技术是二十第一个世纪和新经济的主要司机。力学是在所有超群的技术的一个必要元素。在力学研究机会,教育和挑战,包括在材料的nanomechanics,碳nano试管,启发简历的材料,燃料房间,以及改进工程和设计的试验性、数字、分析的方法在这被介绍并且讨论纸。
简介:NowadaysComputationalFluidDynamics(CFD)softwareisadoptedasadesignandanalysistoolinagreatnumberofengineeringfields.Wecansaythatsingle-physicsCFDhasbeensufficientlymaturedinthepracticalpointofview.ThemaintargetofexistingCFDsoftwareissingle-phaseflowssuchaswaterandair.However,manymulti-physicsproblemsexistinengineering.Mostofthemconsistofflowandotherphysics,andtheinteractionsbetweendifferentphysicsareveryimportant.Obviously,multi-physicsphenomenaarecriticalindevelopingmachinesandprocesses.Amulti-physicsphenomenonseemstobeverycomplex,anditissodifficulttobepredictedbyaddingotherphysicstoflowphenomenon.Therefore,multi-physicsCFDtechniquesarestillunderresearchanddevelopment.Thiswouldbecausedfromthefactsthatprocessingspeedofcurrentcomputersisnotfastenoughforconductingamulti-physicssimulation,andfurthermorephysicalmodelsexceptforflowphysicshavenotbeensuitablyestablished.Therefore,innearfuture,wehavetodevelopvariousphysicalmodelsandefficientCFDtechniques,inordertosuccessmulti-physicssimulationsinengineering.Inthepresentpaper,Iwilldescribethepresentstatesofmulti-physicsCFDsimulations,andthenshowsomenumericalresultssuchasiceaccretionandelectro-chemicalmachiningprocessofathree-dimensionalcompressorbladewhichwereobtainedinmylaboratory.Multi-physicsCFDsimulationswouldbeakeytechnologyinnearfuture.
简介:Thispaperreviewsourworkonthefundamentalprinciplesofhighgravitycontrolledprecipitation(HGCP)technology,anditsapplicationsintheproductionofdrugnanoparticles,whichwascarriedoutinarotatingpackedbed(RPB).Severalkindsofdrugnanoparticleswithnarrowparticlesizedistributions(PSDs)weresuccessfullypreparedviaHGCP,includingthe300-nmCefuroximeAxetil(CFA)particles,200–400-nmcephradineparticles,500-nmsalbutamolsulfate(SS)particles(100nminwidth),and850-nmbeclomethasonedipropionate(BDP)particles,etc.Comparedtodrugsavailableinthecurrentmarket,allthedrugnanoparticlesproducedbyHGCPexhibitedadvantagesinbothformulationanddrugdelivery,thusimprovingthebioavailabilityofdrugs.HGCPisessentiallyaplatformtechnologyforthepreparationofpoorlywater-solubledrugnanoparticlesfororalandinjectiondelivery,andofinhalabledrugsforpulmonarydelivery.Consequently,HGCPofferspotentialapplicationsinthepharmaceuticalindustryduetoitscost-effectiveness,efficientprocessingandtheeaseofscaling-up.
简介:Inthispaper,weextendanovelunconstrainedmultiobjectiveoptimizationalgorithm,so-calledmultiobjectiveextremaloptimization(MOEO),tosolvetheconstrainedmultiobjectiveoptimizationproblems(MOPs).Theproposedapproachisvalidatedbythreeconstrainedbenchmarkproblemsandsuccessfullyappliedtohandlingthreemultiobjectiveengineeringdesignproblemsreportedinliterature.Simulationresultsindicatethattheproposedapproachishighlycompetitivewiththreestate-of-the-artmultiobjectiveevolutionaryalgorithms,i.e.,NSGA-II,SPEA2andPAES.ThusMOEOcanbeconsideredagoodalternativetosolveconstrainedmultiobjectiveoptimizationproblems.
简介:Wehavedesignedaphotoelectricityorientsystemtocontrolnucleiphysicsexperiments.InthispaperIwillintroduceitssoftware.ThisphotoelectricityorientsystemicsoftwareisdesignedbyClanguage.ExploitationenvironmentisTurboCofBorlandInc.HelpdesigninstrumentisPlayCase.TheblockdiagramofthissoftwareisgiveninFig.1.
简介:RigidFiniteElementMethod(RFEM)wasproposedtosimulatethemechanicalbehaviorofdiscontinuousstructuressuchasrockandsoilstructures.Theauthors’workonthetheoryandapplicationsofRFEMissummarizedinthispaper.BasedonthetheoryofRFEM,theElasticBody-SeamsModel(EBSM)isproposedtotakethedeformationanddamageofrockmassesintoaccount.
简介:HL-2AisanewdivertortokamakunderconstructionatSouthwesternInstituteofPhysics(SWIP),Chengdu,China,basedontheexperiencefromHL-1andHL-1M.HListheshorttermofaChinesewordthatmeans"ToroidalCurrentDevice".ThemainobjectivesofHL-2Aaretoproducemoreadaptabledivertorconfigurationstostudyenergyexhaustandimpuritycontrol(thefirstdivertortokamakplasmainChina),andtostudyenhancedplasmaconfinementbyprofilecontrolandmoderateplasmashaping.
简介:ThedevelopmentandmaintenanceofthecontrolsystemsofthefourLargeHadronCollider(LHC)experimentswillrequireanon-negligibleamountofresourcesandeffort.InordertominimisetheoveralleffortrequiredtheJointControlsProject(JCOP)wasset-upasacollaborationbetweenCERNandthefourLHCexperimentstofindandimplementcommonsolutionsforthecontroloftheLHCexperiments.ItisoneofthefewexamplesofsuchawidecollaborationandthereforetheexistenceoftheJCOPprojectisextremelysignificant.Thispaperwillgiveabriefoverviewoftheproject,itsstructureanditshistory.Itwillgoontosummarisethevarioussub-projectsthathavebeeninitiatedundertheauspicesofJCOPtogetherwiththeircurrentstatus.ItwillhighlightthattheJCOPgeneralprincipleistopromotetheuseofindustrialsolutionswhereverpossible.However,thisdoesnotruleouttheprovisionofcustomsulutionswhennon-standarddevicesorverylargenumbersofdeviceshavetobecontrolled.ThepaperwillalsodiscussthearchitectureforeseenbyJCOPandwhereinthisarchitecturethevarioustypesofsolutionsareexpectedtobeused.Finally,althouththeselectionofcommonindustrialandcustomsolutionsisanecessaryconditionofrJCOPtosucceed,theuseofthesesolutionsinthemselveswouldnotnecessarilyleadtotheproductionofhomogeneouscontrolsystems,Therefore,thepaperwillfinishwithadescriptionoftheJCOPFramework,whichisbeingdevelopedtopromotetheuseofthesecommonsolutions,toireducethedevelopmenteffortrequiredbythevariousexperimentdevelopmentteamsandtohelptobuildandintegratecontrolsystemswhichcanbemoreeasilymaintained.
简介:Backgroundknowledgeisimportantfordatamining,especiallyincomplicatedsituation.Ontologicalengineeringisthesuccessorofknowledgeengineering.Thesharableknowledgebasesbuiltonontologycanbeusedtoprovidebackgroundknowledgetodirecttheprocessofdatamining.ThispapergivesacommonintroductiontothemethodandpresentsapracticalanalysisexampleusingSVM(supportvectormachine)astheclassifier.GeneOntologyandtheaccompanyingannotationscomposeabigknowledgebase,onwhichmanyresearcheshavebeencarriedout.MicroarraydatasetistheoutputofDNAchip.WiththehelpofGeneOntologywepresentamoreelaborateanalysisonmicroarraydatathanformerresearchers.Themethodcanalsobeusedinotherfieldswithsimilarscenario.
简介:TheobjectiveoftheApollonprojectisthegenerationof10PWpeakpowerpulsesof15fsat1shot/minute.InthispapertheApollonfacilitydesign,thetechnologicalchallengesandthecurrentprogressoftheprojectwillbepresented.
简介:ThedevelopmentandmaintenanceofthecontrolsystemsofthefourLHCexperimentswillrequireanon-negligibleamountofresourcesandeffort.TheJointControlsProject(JCOP)[1]hasbeenset-upasacollaborationbetweenCERNandthefourLHCexperimentstofindcommonsolutionsfortheLHCexperiments'controlsystems.AlthoughtheJCOPgeneralprincipleistopromotetheuseofindustrialssoluitionswhereverpossible,customsolutionsarestillrequiredwhennon-standarddevicesorverylargenumbersofdeviceshavetobecontrolled.Furthermore.toeasethedevelopmentandintegrationofbothstandardandnon-standarddevicesintothecontrolsystemanumberofsoftwareFrameworksareunderdevelopment.ThispaperwilldescribethevarioussolutionsbeingproposedbyJCOPincludingtheSupervisoryandFront-Endframeworksaswellasthevariousindustrialandcustomcomponents.Inaddition,ItwillalsodescribewherethesefitintotheforeseenJCOPcontrolsarchitecture.ThepaperwillthenhighlightinmoredetailtheFront-EndFramework.
简介:Interestinthenonlinearpropertiesofmulti-modeopticalwaveguideshasseenarecentresurgenceonaccountofthelargedimensionalityaffordedbytheplatform.Thelargevolumeofmodesinthesewaveguidesprovidesanewspatialdegreeoffreedomforphasematchingnonlinearopticalprocesses.However,thisspatialdimensionisquantized,whichnarrowstheconversionbandwidthsofintermodalprocessesandconstrainsspectralandtemporaltailoringofthelight.Hereweshowthatbyengineeringtherelativegroupvelocitywithinthespatialdimension,wecantailorthephase-matchingbandwidthofintermodalparametricnonlinearities.Wedemonstrategroup-velocity-tailoredparametricnonlinearmixingbetweenhigher-ordermodesinamulti-modefiberwithgainbandwidthsthataremorethananorderofmagnitudelargerthanthatpreviouslythoughtpossibleforintermodalfour-wavemixing.Asevidenceofthetechnologicalutilityofthismethodology,weseedthisprocesstogeneratethefirsthigh-peak-powerwavelength-tunableall-fiberquasi-CWlaserintheTi:sapphirewavelengthregime.Moregenerally,withthecombinationofintermodalinteractions,whichdramaticallyexpandthephase-matchingdegreesoffreedomfornonlinearoptics,andintermodalgroup-velocityengineering,whichenablestailoringofthebandwidthofsuchinteractions,weshowcaseaplatformfornonlinearopticsthatcanbebroadbandwhilebeingwavelengthagnostic.