简介：Reiter'ssyndromeisasecondarydiseaseofurethrainfection.Itconsistsofurethritis,nonsuppurativearthritis,conjunctivitisandcutaneousmucosalesions.YoungmalesaremorelikelytogetReiter'ssyndromethanfemales.Thusfar,therearenoreportsofwomeninChinawithReiter'sSyndrome.ThisreportdocumentstwofemaleswithReiter'sSyndrome.

简介：Objectives:TocharacterizethedistributionpatternofbiovarsandserotypesofUreaplasmaurealyticuminnormalhealthywomen,sexuallytransmittedinfectionsclinicclients,andinsexworkers.Methods:Weculturedcervicalswabstakenfrom261physicalcheck-upclients,599STIclinicoutpatientsand98sexworkersusingcommercialselectivemedium.SomepositivecultureswerefurtherbiotypedandserotypedbyPCR.Results:(1)U.urealyticumismorecommonlyisolatedinsexworkers(90.8%)thaninthephysicalcheck-upgroup(60.9%)ortheSTIoutpatientgroup(61.3%)(P<0.001).(2)Biovar1ofU.urealyticum(95.0%),especiallysingleinfectionofserotype1,3,and6ofbiovar1,iscommonlyfoundinhealthywomen.(3)Biovar2infectionofU.urealyticumismoreprevalentinsexworkers(28.1%)andSTIoutpatientsgroup(26.6%)thanthatinthephysicalcheck-upgroup(4.9%)(P<0.001).(4)MixedinfectioncausedbymorethanoneserotypeofU.urealyticumincreasedfromphysicalcheck-upgroup(8.6%)toSTIoutpatients(12.4%)tosexworkers(23.9%)(P<0.01).(5)Thereisnostatisticallysignificantdifferenceinthedistributionofserotype1,3,and6ofbiovar1amongthesethreegroups(P=0.763).(6)ThePCRmethoddescribedhereisrelativelysimple,rapidandspecificforthebiotypingandserotypingofbiovar1ofU.urealyticum.Conclusion:Weshouldpaymoreattentiontobiovar2andmixedinfectionsofU.urealyticumthansingleinfectionofbiovar1inclinicpractice.PCRisagoodmethodforbiotypingandserotyping.

简介：Objective:Tofindoutthebasicconditionsofmycosisinfectionoffull-termpregnantwomen.Methods:Fungusisolationandidentificationfromthevaginalsecretionsandoralspecimensfrom208full-termpregnantwomenwerecarriedoutbyfungicultureandidentifiedfollowingstandardbiologicalpractice.Results:Thepositivedetectionrateforvaginalfungiwas51.92%andfororalfungiitwas47.59%.20.19%hadfungiinboththevaginalandoralcavity.ThefungifoundweremainlyofthespeciesCandidaalbicans.Conclusion:Theprevalenceoffungalmycosisinfectioninfull-termpregnantwomenwashigherthanthatusuallyfoundinnon-pregnantwomen.Inordertopreventfurthercomplicationsandmateral-childtransmission,seriousattentionshouldbepaidtothishighprevalencefinding.

简介：Objective:ToinvestigateU.parvum(previouslyUreaplasmaurealyticumbiovar1)andU.urealyticum(previouslyUreaplasmaurealyticumbiovar2)andtheirsubtypesandserovarsinurinespecimensofpregnantwomen.Methods:Aftercollecting151specimensandinoculatingbroth,allbrothculturepositive(ureasepositive)specimenswereamplified,specieswereidentifiedandsubtypedbyusinggeneralprimers,species-specific,andtype-specificprimerstargetingthemultiplebandedantigen(MBA)genesequence.Results:U.parvumwasidentifiedin58of151specimensandU.urealyticumin18(bothwerepresentin5,andneitherwerefoundin6).Serovars3,1,and6werethemostcommonamongU.parvumisolatesandsubtypes1and3werethemostcommonamongU.urealyticum.Multipleserovarsamongclinicalisolateswerefound.Conclusion:ThisPCR-basedtypingsystemcouldfacilitatestudiesoftherelationshipbetweenindividualureaplasmaspeciesorsubtypesandhumandiseases.

简介：AbstractBackground:TheNnewlyreportedcasesofcongenitalsyphilishavebeenincreasedingsubstantiallyoverthepastfewyears.Tocontroltheepidemic,amunicipalprogramaimedatpreventingmother-to-childtransmissionofsyphiliswasintroducedinJuly,2001,whichwasdesignedaimedtoscreenallpregnantwomenforsyphilisattheirfirstvisittoantenatalclinicsoratadmissiontohospitalsinShenzhen.Objectives:TheaimofthestudyistTodeterminetheprevalenceofsyphilisamongwomenattendingantenatalclinicsandothermedicalinstitutionsinShenzhenandidentifiesitspatternsofinfection.Methods:Upongivinginformedconsent,wWomenwhoattendedantenatalcarecentersinShenzhenfromJanuarytoDecember2003wereincludedinthisstudysubjecttoobtaininginformedconsent.AbloodsamplewasharvestedforsyphilisscreenedforsyphUisingbyusingrapidplasmareagenttest(RPR)andconfirmedbyTPHAforthosewhowereRPRpositive.Thewomenwithpregnantsyphilispositiveserologyweresystematicallyinterviewedtoobtain.Duringtheinterview,theirdemographicdetailsinformation,patternsofriskbehaviorsandotherdata.Datawerecollectedandwereanalyzedretrospectively.Results:AmongOf118,235pregnantwomensurveyed,555pregnantwomenwereconfirmedtohavesyphilis(prevalenceof4.69%),withaincidenceof4.69‰123womenwereexcludedfromtheanalysisbecauseofincompletemedicalrecords.Of432infectedsubjectswithcompletemedicalrecords,theaverageagewas26.8,witharangeof19to41.7.41%(32/432)ofthemsufferedfromprimarysyphilis,3.24%(14/432)wereofhadsecondarysyphilis,and89.35%(386/432)hadlatentsyphilis,withoutanyconspicuousclinicalsignsandsymptoms.Conclusions:Theprevalenceofsyphilisamongthepregnantwomeninourserieswashighandmostofthemwereasymptomatic.ScreeningforsyphilisamongpregnantwomeninShenzhenisofimportantceforthepreventionofmother-to-childtransmissionofsyphilis.

简介：Objectives:Todeterminetheaetiologiesofvaginaldischargesyndromes,tocalculatetheperformanceofdifferentmanagementalgorithms,andvalidatethesealgorithmsinSTDclinicsinChina.ThesealgorithmswereadoptedfromthoseproposedbytheWorldHealthOrganization.Methods:Atotalof315consecutivepatientswithvaginaldischargewereenrolledatthreeSTDclinics.CervicalinfectionwasdefinedaspresenceofNeisseriagonorrhoeaeoncultureand/orChlamydiatrachomatisbypolymerasechainreaction.OtherlaboratorytestsincludedwetmountmicroscopyandpHtestingofvaginalfluid.Sensitivity,specificity,andpositivepredictivevalueofdifferentalgorithmsweredeterminedusingstandardmethods.Results:Cervicalinfectionwasidentifiedin37.8%ofpatients(20.6%gonorrhea,12.7%chlamydialinfection,4.4%gonorrheaincombinationwithchlamydialinfection).Thesensitivity,specificity,andpositivepredictivevalueofalgorithmsAandBfortheidentificationofNeisseriagonorrhoeaeand/orChlamydiatrachomatiswererespectively71.4%and90.8%,65.3%and46.9%,55.6%and50.9%.Conclusions:Thevaginaldischargealgorithmscouldbeappliedforclinicalmanagement.Theirsensitivitiesareacceptable.However,thereisaneedtofurtherimprovetheirspecificityandpositivepredictivevalue.Thetwoalgorithmscouldbeusedinclinicalsettingswithdifferentfacilities.Thesealgorithmsshouldalsobevalidatedinpopulationswithlowerdiseaseprevalence.