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简介：我们现在的kth顺序纠纷措施和全球kth顺序纠纷为多国参加的纯状态测量，并且为由两部组成的纯状态扩大班尼特部分熵的措施到一个多国参加的盒子。这些措施是可计算出来的并且能有效地分类并且确定多国参加的纯状态的纠纷。

简介：Inthispaper,afacialfeatureextractingmethodisproposedtotransformthree-dimension(3D)headimagesofinfantswithdeformationalplagiocephalyforassessmentofasymmetry.Thefeaturesof3Dpointcloudsofaninfant’scraniumcanbeidentifiedbylocalfeatureanalysisandatwo-phasek-meansclassificationalgorithm.The3Dimagesofinfantswithasymmetriccraniumcanthenbealignedtothesamepose.Themirroredheadmodelobtainedfromthesymmetryplaneiscomparedwiththeoriginalmodelforthemeasurementofasymmetry.Numericaldataofthecranialvolumecanbereviewedbyapediatriciantoadjustthetreatmentplan.Thesystemcanalsobeusedtodemonstratethetreatmentprogress.

简介：Thestiffnessandstrengthofextracellular(EC)regionofcadherinareproposedtobetwoimportantmechanicalpropertiesbothforcadherinasamechanotransductorandfortheformationofcell-celladhesion.Inthisstudy,wequantitativelycharacterizedthestiffnessandstrengthofECstructurewhenitbindswithdifferenttypesofionsbymoleculardynamicssimulations.ResultsshowthatECstructureexhibitsarod-likeshapewithhighstiffnessandstrengthwhenitbindswiththebivalentionsofcalciumormagnesium.However,itswitchestoasoftandcollapsedconformationwhenitbindswiththemonovalentionsofsodiumorpotassium.ThisstudyshedslightontheimportantroleofthebivalentionsofcalciuminthephysiologicalfunctionofEC.

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简介：目前,各国建筑抗震设计规范对结构在“大震”下倒塌概率的评估尚不完善.FEMAP695以美国现行规范为基础,提出了一套用于标定其建筑抗震设计规范中关键设计参数的方法,用以保证结构在“大震”下的倒塌概率不超过某一可接受的值.介绍了美国建筑抗震设计规范的理论基础,说明了FEMAP695中关键参数的定义与美国现行抗震规范中设计参数的关系,详细介绍了该方法的基本内容、方法流程、关键细节、理论思路等,为了解美国抗震规范的发展方向及水平提供了参考.

简介：这份报纸建议一个新奇方法确定为errorsin-的一个名字的规范的正确的图符号(NRGS)的错误与围住的噪音贿赂的变量(EIV)系统。为设置的一个不安模型，的评价跟随一个鉴定框架为估计的名字的NRGS的最坏的v差距错误界限能首先从内在的EIV系统上的priori和一个posteriori信息被决定。然后，一个NRGS不安模型集合能从在二个模型的v差距度量标准和他们的NRGS差别的H-norm之间的一种靠近的关系被导出。获得的NRGS不安模型集合用H为柔韧的控制器设计铺平道路塑造环的方法因为它是著名NCF(规范的coprime因素)的一种标准形式，不安模型设定。最后，数字模拟被用来表明建议鉴定方法的有效性。

简介：在为comagmatic金矿床(CGD)的成岩作用和矿化作用(TGDM)之间的时间差距在证实在金矿床和他们的相关侵入之间的基因关系起一个重要作用。在在中国的某典型金矿床和他们的相关岩石的昂贵地出版的同位素年龄的帮助下，作者讨论了并且确定分发特征和TGDM的范围。统计分析和Kolmogorov测试证明使矿物化的事件是也同时期的与或稍微填迟他们的血缘的岩浆。TGDM与7.0妈的一个平均数在在0和16.0妈之间的0.05信心水平和簇符合正常分布。因此，如果CGD的TGDM是不到16.0妈，考虑是合理的，在另外的证据的帮助下，它的comagmatic的可能性基因联营。作者也强调存款的地质的背景学习了得到加强成岩作用矿化作用，并且与痕量元素并且同位素跟踪在联合注意时间差距的学习是必要的精确时间差距。

简介：AbstractThe common cerebral small vessel disease (CSVD) neuroimaging features visible on conventional structural magnetic resonance imaging include recent small subcortical infarcts, lacunes, white matter hyperintensities, perivascular spaces, microbleeds, and brain atrophy. The CSVD neuroimaging features have shared and distinct clinical consequences, and the automatic quantification methods for these features are increasingly used in research and clinical settings. This review article explores the recent progress in CSVD neuroimaging feature quantification and provides an overview of the clinical consequences of these CSVD features as well as the possibilities of using these features as endpoints in clinical trials. The added value of CSVD neuroimaging quantification is also discussed for researches focused on the mechanism of CSVD and the prognosis in subjects with CSVD.

简介：AbstractBackground:Diabetes mellitus (DM) is considered a cardiovascular risk factor. The aim of this study was to analyze the prevalence and volume of coronary artery plaque in patients with diabetes mellitus (DM) vs. those without DM.Methods:This study recruited consecutive patients who underwent coronary computed tomography (CT) angiography (CCTA) between October 2016 and November 2017. Personal information including conventional cardiovascular risk factors was collected. Plaque phenotypes were automatically calculated for volume of different component. The volume of different plaque was compared between DM patients and those without DM.Results:Among 6381 patients, 931 (14.59%) were diagnosed with DM. The prevalence of plaque in DM subjects was higher compared with nondiabetic group significantly (48.34% vs. 33.01%, χ2 = 81.84, P < 0.001). DM was a significant risk factor for the prevalence of plaque in a multivariate model (odds ratio [OR] = 1.465, 95% CI: 1.258-1.706, P < 0.001). The volume of total plaque and any plaque subtypes in the DM subjects was greater than those in nondiabetic patients significantly (P < 0.001).Conclusion:The coronary artery atherosclerotic plaques were significantly higher in diabetic patients than those in non-diabetic patients.

简介：在结构性质的无常能在混合模拟导致不同回答。这些无常的效果的Quantification将使研究人员能估计从实验观察的结构的回答的变化。这由于致动器延期的存在为即时混合模拟(RTHS)提出挑战。模型在直角的随机的多项式的一个基础上输出说明模型无常的影响的多项式混乱扩大(PCE)工程。在这份报纸，PCE被利用从自由(SDOF)的单个度的即时混合模拟在最大的排水量上评估致动器延期的效果结构什么时候为在结构的性质的无常的财务。PCE是没有延期，首先申请了RTHS为系数决定PCE，样品点的数字以及方法的顺序计算。PCE然后与致动器延期被用于RTHS。平均数，变化和Sobol索引被比较并且讨论了为RTHS在无常quantification上评估致动器延期的效果。结果证明平均数和最大的排水量的变化分别地关于致动器延期线性地并且指数地增加。通过Sobol索引的敏感分析也显示当联合效果随致动器延期的增加增加时，单个随机的变量的影响减少。

简介：Thepresentstudywasanefforttounderstandtheamountoflitterfallanditssubsequentdecompositionandquantifythereleaseofavailablenutrientsandsoilphysicochemicalcharacteristicsinplantationsoffourforesttreespecies(Lagerstroemiaparviflora,Tectonagrandis,ShorearobustaandMicheliachampaca)intheChilapattaReserveForestoftheCoochBeharWildlifeDivisionintheTeraizoneofWestBengal,India.Themostlitter(5.61Mgha-1)wasproducedbyT.grandisplantationandtheleast(4.72Mgha-1)byL.parviflora.Thematerialturnoverratetothesoilthroughdecompositionfromtotallitterwasfastestduringthefirstquarteroftheyearandsubsequentlydecreasedduringthenexttwoquarters.Thematerialturnoverratewasonly1year,whichindicatesthatmorethan90%ofthetotallitterproduceddecomposedwithinayear.Theavailableprimarynutrientcontentinlittervariedacrossthefourplantationsovertheyear.Theplantationsgenerallydidnotsignificantlyinfluencethesoilphysicalcharacteristicsbutdidsignificantlyinfluencetheavailabilityofprimarynutrientsandorganiccarbonattwodepths(1-15and16-30cm)overtheyear.Theavailabilityofsoilprimarynutrientsinthefourplantationsalsoincreasedgraduallyfromthefirstquarteroftheyeartothethirdquarterandthendecreasedduringthelastquartertothesamelevelasinthefirstquarteroftheyearatbothdepths.Theavailabilityforsoilorganiccarbonintheplantationsfollowedasimilatrend.Theamountoflitterproducedandthematerialturnoverinthesoilinthedifferentplantationsdiffered,influencingthenutrientavailabilityandorganiccarbonattheplantations.TheamountofsoilorganiccarbonwashighestforT.grandis(2.52Mgha-1)andlowestforL.parviflora(2.12Mgha-1).Litteristhesourceofsoilorganicmatter,andmorethelitterthatisproducedbytheplantations,thehigherwillbethecontentandamountofsoilorganiccarbonintheplantation.

简介：Thereversetranscriptase(RT)proteinofhepatitisBvirus(HBV)hasbeensuccessfullyexpressedbyrecombinanttechnologyinEschericahiacoli(E.coli).Inthisstudyweaimedtodevelopasemi-quantitativeassayforthestudyofHBVRTproteinusingthissystem.CompleteHBVpolymerasegenefromawildtypevirus(rt306P)andthepolymerasegenefromamutant,withrt306Psubstitutedbyserine(rtP306S)wereseparatelyfusedtothemaltosebindingprotein(MBP)geneandexpressedinE.colirespectively.TheexpressionlevelsofHBVpolymerasegenesfromthewildtypevirusanditscounterpartmutantatrt306werecompared.Whentheseproteinsweresemi-quantifiedbyWesternblottingusingrabbitanti-TPserum,thertP306SmutantshoweddecreasedexpressionofMBP-HBVpolymerase.Bythismethod,wehaveshownthattheexpressionlevelofHBVRTcouldbeaffectedbysubstitutionsinitsaminoacidsequences,andthismethodcouldbeusedtostudythecharacteristicsofHBVRTprotein.

简介：这篇论文主张那基于代理人的模拟能为设计处理人的反应从的方法的严峻的Kansei被用作一个方法对心理状态感觉，也就是说敏感，感觉，敏感，感情，esthetics，情感爱；直觉。一个新模糊线性数量化离子方法被基于代理人的建模在一个人工的世界上测试；模拟，；模糊线性方法的表演与一个基因算法的相比。模拟能扩展人的想象力；提高人新模糊线性数量化离子方法是有效的直觉。

简介：Background:Accelerometershavebeensuggestedtoprovideadditionalinformationduringthe6-minwalktestwhichmaybeusefulinevaluatingchangesinfunctionalexercisecapacity.TheaimofthestudywastoidentifywhethertheadditionalinformationmeasuredbytheMyWellnessKey~(TM)(MWK)accelerometerduringatreadmill6-minwalktest(t-6MWT)wasrelatedtocurrentlyusedoutcomemeasures.Methods:Fifteenparticipants(9males,6females)performedaself-pacedt-6MWT.RespiratorygasanalysisandwalkingdistanceweremeasuredwhilstwearingtheMWK.Results:Asignificantcorrelationwasestablishedbetweenactivitycountsand6-minwalkdistance(6MWD)(r=-0.847,p<0.001)yetnot6-minwalkwork(6MWW)(r=-0.337,p=0.220).EnergyexpenditureestimatedbytheMWKwasstronglycorrelatedto6MWW(r=0.938,p<0.001)butnot6MWD(r=0.477,p=0.072).TheMWKsignificantlyunderestimatedenergyexpenditure(36.73,CI=33.9-39.7kcal)comparedtogasanalysis(54.35,CI=46.2-61.4kcal)demonstratingpooragreementbetweenthetwoanalyses(Bias=-17.61kcal,Limitsofagreement=-37.4,t2.2kcal).Measurementoftimespentundertakinglight,moderate,andvigorousphysicalactivitywasnotsignificantlydifferent(p>0.05)betweentheMWKandgasanalysis.Conclusion:EstimatedenergyexpenditureprovidedbytheMWKwasstronglycorrelatedto6MWW;however,MWKunderestimatedenergyexpenditureasmeasuredbygasanalysis.TheMWKmayprovideoutcomedatathatsupplementthosecurrentlyprovidedbythe6MWDforfunctionalcapacityassessmentduringthet-6MWT.

简介：提炼棕色的planthopper(BPH)，Nilaparvatalugens圣?l，是米饭的最破坏的害虫之一，被证实了在胖身体怀有似酵母的symbiotes(YLS)。几词法上不同的YLS以前被孤立并且在从BPH的vitro有教养，却直接证据正在缺乏进一步澄清有教养的YLS是否从BPH。在这研究，YLS的一种在vitro是成功地有教养的并且同时验证了由顺序分析在BPH的胖身体存在并且嵌套聚合酶链反应(PCR)。有教养的YLS在vitro孤立根据18SrDNA(ribosomalDNA)和5.8S-ITS(内部抄录分隔符)作为类Candida的一个成员被识别rDNA顺序和它从酵母的序列的种系发生的分析。因此，这酵母孤立作为象Candida一样symbiotes被说出。象Candida一样symbiotes被发现在胖身体，卵巢和BPH的最新生的卵，然而并非在头，存在胸并且中间勇气。另外，在1а的象Candida一样symbiotes的数字

简介：ObjectivesTodevelopasimple,accurateandreproduciblemethod,whichcombinesmacroandhistopathologicaltechniquesfordeterminingthedegreeoflipiddepositioningeneticallymodifiedmice.MethodTheentireaortasfromC57BL/6,ldlr-/-andapoE-/-micewerestainedwithSudanⅣusingeitherinvivoperfusionortraditionalinvitroenfacestainingtechniques.Histologicalsectionsofaorticrootandheartswereembeddedintissuefreezingmediumandcutwithacryostat,thenstainedwithOilRedO.Thecalculatedaorticrootareabasedontheaorticrootcircumferencewasusedtoreducemeasurementerrors.ResultsTheinvitroenfacestainingcanstainallfat,whichincludetheadventitialtissuearoundaorta.Howevertheinvivoperfusionstainingcanspecificallystainthefattydepositioninsideofaorta.Bothentireaortaandaorticrootsectionstainingshowedthattherewasahighlysignificantincreaseinfattydepositionintheaortasofthegeneticmodifiedmice.Althoughallmicegeneticbackgroundwassame,theapoE-/-micehadlargeratheroscleroticlesionsthanldlr-/-mice.ConclusionsThenewinvivoperfusionmethodismoreaccuratethantheinvitroenfacemethod.Thecombinationofthesemacroandmicroscopictechniquesovercomestheshortcomingsoftheearlierpublishedmethodswhicharegenerallylimitedtothemeasurementoffattyredstainingareasonly,neglectingnon-specificadventitialfatstainingaroundaortaandaorticrootsectiontissuedistortion.