简介:AbstractBackground:Intravenous thrombolysis (IVT) is an effective way for treating acute ischemic stroke (AIS). However, its effects have not been established among AIS patients with unclear stroke symptoms or with stroke onset for >4.5 h.Methods:We searched PubMed, Embase, Web of Science, Cochrane Central Register of Controlled Trials and Google Scholar databases for randomized controlled trials that compared IVT (IVT group) and placebo or usual care (control group [CG]) in AIS patients with disease onset for >4.5 h. The outcomes of interest included the favorable functional outcome (defined as modified Rankin Scale [mRS] scores 0-1) at 90 days, the functional independence (defined as mRS scores 0-2) at 90 days, proportion of patients with symptomatic intracerebral hemorrhage (sICH) and death at 90 days. We assessed the risk of bias using the Cochrane tool. Pre-specified subgroup analyses were performed by age (≤70 years or >70 years), National Institute of Health Stroke Scale (NIHSS, ≤10 or >10) and time window (4.5-9.0 h or >9.0 h).Results:Four trials involving 848 patients were eligible. The risk of bias of included trials was low. Patients in the IVT group were more likely to achieve favorable functional outcomes (45.8% vs. 36.7%; OR 1.48, 95% CI 1.12-1.96) and functional independence (63.8% vs. 55.7%; OR 1.43, 95% CI 1.08-1.90) at 90 days, but had higher risk of sICH (3.0% vs. 0.5%; OR 5.28, 95% CI 1.35-20.68) at 90 days than those in the CG. No significant difference in death at 90 days was found between the two groups (7.0% vs. 4.1%; OR 1.80; 95% CI 0.97-3.34).Conclusions:Use of IVT in patients with extended time window may improve their functional outcomes at 90 days, although IVT may induce increased risk of sICH. Care of these patients should well balance the potential benefits and harms of IVT.
简介:Thecoherencecubetechnologyhasbecomeanimportanttechnologyfortheseismicattributeinterpretation,whichextractsthediscontinuitiesoftheeventsthroughanalyzingthesimilaritiesofadjacentseismicchannelstoidentifythefaultform.Thecoherencecubetechnologywhichusesconstanttimewindowlengthscannotbalancetheshallowlayersandthedeeplayers,becausethefrequencybandofseismicdatavarieswithtime.Whenanalyzingtheshallowlayers,thetimewindowwillcrossoveralotofevents,whichwillleadtoweakfocusingabilityandfailuretodelineatethedetails.Whilethetimewindowwillnotbelongenoughforanalyzingdeeplayers,whichwillleadtolowaccuracybecausethecoherencesnearthezeropointsoftheeventsareheavilyinfluencedbynoise.Forsolvingtheproblem,weshouldmakearesearchonthecoherencecubetechnologywithself-adaptivetimewindow.Thispaperdeterminesthesamplepoints’timewindowlengthsinrealtimebycomputingtheinstantaneousfrequencybandswithWaveletTransformation,whichgivesacoherencecomputingmethodwiththeself-adaptivetimewindowlengths.Theresultshowsthatthecoherencecubetechnologywithself-adaptivetimewindowbasedonWaveletTransformationimprovestheaccuracyoffaultidentification,andsupressesthenoiseeffectively.Themethodcombinestheadvantagesoflongtimewindowmethodandshorttimewindowmethod.
简介:AWindowonTibetanCultureGELEGThelastfewcenturiessawnumerouspeopleventUreintoTibet,aholylandtuckedawayontheRoofoftheWorld.Howev...
简介:OpeningtheWindowforTibetanArt¥//Thisyearmarksthe30thanniversaryofthefoundingoftheTibetAutonomousRegion.China'sTibetiscelebrat...
简介:Windowcoatingusedforthebuildinginrecentyearsisdescribed.Importantdesignprinciples,practicalcoatingmaterials,andattainableopticalpropertiesforresearch-typecoatingsareintroduced.Discussioniscarriedoutonthespectrallyselectivecoatings,theelectrochromiccoatings,andthethermochromiccoatings.
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简介:这篇文章为溪流控制转移提出一个算法有有限接收装置缓冲区(RBUF)的协议(SCTP)改进。这是众所周知的,SCTP是最重要的转移控制协议之一,但是大多数研究集中于没有RBUF限制的状况。在这研究,我们在表演上分析RBUF尺寸的影响。计算机模拟证明网络实用程序在可靠转移是低的,当RBUF尺寸比带宽延期产品小时。由学习传播顺序数字(TSN)转移进步,我们发现同伴接收装置窗户(PEER_RWND)落后于真接收装置窗户(RWND),导致差的网络用途。与有限RBUF改进SCTP性能,虚拟接收装置窗口(VIRTUAL_RWND)被介绍。基于VIRTUAL_RWND,一个算法被建议增加送的率。计算机模拟在两个评估了建议算法的优秀表演没有失去的包的理想的连接和有失去的包的非理想的连接。
简介:Anewwaveletvarianceanalysismethodbasedonwindowfunctionisproposedtoinvestigatethedynamicalfeaturesofelectroencephalogram(EEG).TheexprienmentalresultsshowthatthewaveletenergyofepilepticEEGsaremorediscretethannormalEEGs,andthevariationofwaveletvarianceisdifferentbetweenepilepticandnormalEEGswiththeincreaseoftime-windowwidth.Furthermore,itisfoundthatthewaveletsubbandentropy(WSE)oftheepilepticEEGsarelowerthanthenormalEEGs.
简介:Launchedin2002,theHumanRightsmagazineoperatesundertheauspicesoftheChinaSocietyforHumanRightsStudies,anon-governmentalorganizationinSPECIALconsultativestatuswiththeEconomicandSocialCounciloftheUnitedNations.ThemagazineisthefirstofitskindeverpublishedinChina.Whiledevotedtotheoreticalstudiesofhumanrightsandhumanrightseducation,itprovidesaforumfordialoguebetweenChinaandforeigncountriesonhumanrights-relatedissues.