简介：自发的oligoasthenoteratozoospermia(i燕麦)影响约30%所有不肥沃的人。这微型评论在这域里讨论了最近的数据。年龄，在testicular以后机关的非煽动性的功能的改变，传染物(Chlamydiatrachomatis，疱疹病毒和联系adeno的病毒)，在配偶子染色体的改变，mitochondrial改变，环境污染物质和“微妙”的神经质的改变都被认为i燕麦的可能的原因。在小管并且在精液的血浆并且apoptosis的反应的氧种类的增加是被认为的影响精子集中，活动性和形态学。i燕麦被排除通常诊断，但光谱主要阴囊的动脉的踪迹可以为i被用作一个诊断工具燕麦。下列能为i燕麦被认为治疗：1)tamoxifen柠檬酸盐(20mg/d)+睾丸激素undecanoate(120mg/d)(妊娠率每夫妇/月[prcm]：3.8%)；2)folic(66mg/d)+硫酸锌(5mg/d)；3)L肉毒碱(2g/d)独自或在有acetyl-L-carnitine(1g/d)的联合(prcm：2.3%)；并且4)两肉毒碱=一个30mgcinnoxicam栓剂每4天(prcm：8.5%)。堵住Alpha药改进了精子集中然而并非形态学，活动性或妊娠率。Tranilast(300mg/d)在起始的不受管束的研究增加了精子参数和妊娠率。它精子集中上的功效(然而并非在精子活动性，形态学或prcm上)在随后的出版报告被证实。tamoxifen+睾丸激素undecanoate的功效，tamoxifen独自一个，并且recombinant刺激滤泡的荷尔蒙仍然是为讨论的一件事。

简介：Erectilefailureisparticularlyconmaoninmenwithdiabetes;itaffectsupto30%,andtheprevalenceincreasesfurtherwithage,durationofdiabetes,andthepresenceofmicrovascularandn'kacrovascularcomplications.Itcanbedistressingforboththemanandhispartner.Thereisnowincreasingawarenessoftheimportanceoftheproblem,andtheincreasedefficacyandavailabilityoftreatmentmakesitcorrectableinmorethan80%of

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简介：Themajormatesterilegenesinanewphoto/thermo-sensitivegenicmalesterile(PTGMS)lineB06Sofricewereanalyzedbythemanipulationofmixturedistributiontheory.TheresultsindicatedthatapairofmajormalesterilenucleargeneswithlargeeffectswereresponsibleforcontrollingthemalesterilityofB06S.

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简介：精子chromatin/DNA正直为父亲的基因信息的精确传播是必要的，并且正常精子染色质结构为使肥沃的精子是重要的能力。精液的常规检查，包括精子集中，活动性和形态学，不在精子染色质结构识别缺点。为它的评价的精子DNA损坏和许多方法的起源被描述。精子DNA损坏的评估看起来是为估计男富饶潜力的一个有用工具在活体内和在试管内。后代上的精子DNA缺点的可能的影响也被讨论。

简介：ＷｈｏＨｏｌｄｓＵｐＨａｌｆｏｆＨｅａｖｅｎ？ＭａｌｅＩｎｖｏｌｖｅｍｅｎｔｉｎＦａｍｉｌｙＰｌａｎｎｉｎｇ￥／／Ｗｏｍｅｎｍａｙｈｏｌｄｕｐｈａｌｆｏｆｈｅａｖｅｎｂｕｔ，ｉｎｍｏｓｔｐａｒｔｓｏｆｔｈｅｗｏｒｌｄ，ｔｈｅｙｃａｒｒｙｎｅａｒｌｙ８...

简介：Researchthataddressesmalere-productivehealthshouldassistinthedevelopmentofreproductivehealthprogrammaesandpolicy;identifyandtestnewleadsinnudecontraceptivetechnology;establisheffectivemaleinvolvementinitiativeswhicharelikelytohaveapositiveimpactonthereproductivehealthofmenandwomen;guidetheallocationofhealthcarereourcestoensurecost-effectivenessofinterventions;generatenewknowledge,developdiagnustictechnologyinreproductivehealthandofferoptimaltreatment/careregimens.InconsideringtheneedsanddemandsofnudereproductivehealthresearchinAsiaandthePacific,thefollowingsixresearchtopicsarerecommendedasthepriorityresearchareas:malecontraceptivetechnology;nudereproductivehealthbehaviourandmaleadolescentreproductivehealth;malereproductiveagingincludingmalemenopauseandotherdiseases;maleRTIs,STDs,HIV/AIDS;prevalence,managementandpreventionofnudeinfertility;environmentandsemenqualityandothermalereproductiveproblems.Oneofthemajorchallengesnowfacingusistheelaburationofacomprehensive,yetrealisticmalereproductivehealthresearchagendathatreflecttheneedsanddemandsofAsiandevelopingcountries.Tothisend,tomakeuseofaninterdisciplinaryapproachisofstrategicimportance.Themostcreativeinsightsandproductiveleadsarelikelytoemergefromaresearchteamthatisinteldisciplinaryespeciallyinthefieldofreproductivehealth.(AsianJAndrol1999Jun;1:13-20)

简介：Studiesdemonstrateadeclineinandrogenswithageandthisresultsintheandropause.Theobjectiveofthispaperistoreviewtheliteratureonhormonalchangesthatoccurintheagingmalesanddetermineifthereareassociationsbetweendecreasedtestosterone,dehydroepiandrosterone(DHEA)anddecreasedcognitivefunction.Trialsofandrogenreplacementanditsimpactoncognitivefunctionwillalsobeanalyzed.MethodofanalysiswillbebyathoroughsearchofarticlesonMEDLINE,theIntemetandmajorabstractdatabases.Resultsoftheauthor'sownresearchin302menoftheassociationofmemorylossasasymptomintheandropausewillbepresented.Inaddition,theauthorsopentrialoftestosteronereplacementinhypogonadicmenwithAlzheimer'sdiseasewillalsobepresented.Theresultsoftheauthor'strialwillbecomparedwithotherinvestigators.Highendogenoustestosteronelevelpredictedbetterperformanceonvisualspatialtestsinseveralstudies,butnotinallstudies.Likewise,testosteronereplacementinhypogonadicpatientsimprovedcognitivefunctionsinsomebutnotallstudies.Testosteronehasalsobeenshowntoimprovecognitivefunctionineugonadalmen.SeveralstudieshaveshownthatdeclinesinDHEAmaycontributetoAlzheimer'sdiseaseandtheresultsofdoubleblindstudieswithDHEAreplacementanditseffectoncognitionwillalsobepresented.Insummary,thereisstillnoconsensusthatandrogenreplacementisbeneficialincognitivedeclinebutthisoptionmayprovepromisinginsomepatients.

简介：SolublemalewormantigenofSchistosomajaponicurn(Sj)wasinvestigatedfordevelopmentofnewvaccinecandidate.SDS--PAGEandWesternblottingwereperformedtocomparethedifferencebetweensolubleantigensfromwormsofdifferentsex.MicevaccinationwiththetestingpurifiedproteinwasfollowedbySjcereariaechallengetodetecttheprotectiveeffectagainstSj.Sixteenbandswereseenforthesolublemalewormantigenand12forthefemaleworm.Inaddition,adistinctbandof44.6kDafromthemalewormantigenwasobserved,anditsantigenicitywasdemonstratedbyWesternblotting.This44.6kDaproteincouldinducesignificantwormandeggreductionrateinmice(39.31%,41.98%,P<0.001).Inthisstudya44.6kDaproteinwasisolatedandpartiallycharacterized.Itsantigenicity,immunogenicityandthepartialimmuneprotectionsuggestitspotentialvaccinecandidteagainstSj.

简介：由把OsRacDcDNA用作探查屏蔽光周期的genomic图书馆敏感妖怪男性无菌的米饭行Nongken58S，包含编码OsRacD的区域的2kb倡导者and396bp的积极克隆被获得。与reversePCR从正常米饭变化Nongken58(Nongken58N)克隆的OsRacD的倡导者相比，相同是99.8%，并且不同核苷酸在在倡导者的预言的反应元素外面，建议在在长天的条件下面的米饭变化Nongken58S和Nongken58N之间的富饶是没在OsRacD在上游的规定序列的结构归因于差别，但是到基因的发展规定微分表示。

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简介：1AginginAsia-anavalanchestartstoformWithdecreasingfertilityrateandincreasinglifeexpectancy,theworldisaging-withhighestratesinAsia.Thesocioeconomic,financialandmedicalconsequencesoftheagingpopulationwillbeevenmorepronouncedduetothelimitedresourcesofmanyAsiancountries.DuringtheFirstAsinISSAMMeetingontheAgingMaledistinguishedspeakersdepictedthescenariointhevariouscountriesandproposedsolutionsofhowtomanagetheagingpopulations.

简介：ToselecttheimmunogenicshortpeptidemimicsofmalewormoriginofSchistosomajaponicum(Sj)andtoexploretheirprotectioneffectagainstschistosomiasisinmice,therandomphagedisplaypeptidehbraryof12-merwasscreenedwithIgGtosolublemalewormantigenofSj,andthespecificpositiveclonesselectedthroughthreeroundsofscreeningsweredetectedbyDot-ELISA,andtheninjectedsubcutaneouslyintomiceforvaccinationandprotectionassessmentagainstSj.Itwasfoundthat18randomlypickedphagedisplayedclonesallshoweddefiniteantigenicitywithvariousintensities.Thepooledphagesdisplayedclonescouldinduceproductionofspecificantibodiesandcause31.72%ofwormreductionrateand51.54%ofeggreductionrateinmice,revealingasignificantdifference(P<0.001)incomparisonwiththoseofthecontrols.ItconcludesthattheshortpeptidemimicsofmalewormoriginofSjobtainedbyaffinityscreeningphagedisplayptidelibrarycanelicitpartialprotectionagainstthispathogen.

简介：为了在不同发育阶段调查织物transglutaminase活动，叶子和米饭的年轻圆锥花序的变化，从Honglian-typecytoplasmic不育系，YuetaiA和它的维护者线被切除，YuetaiB分别地。为在米饭的织物transglutaminase活动察觉的一个ELISAmeasurement协议很好被建立。结果显示织物transglutaminase活动被钙阳离子，和织物transglutaminase活动在衰老的叶子断然调整在年轻叶子比那显著地高。没有不同差别在YuetaiA和YuetaiB之间被注意。而且，从四个起核心作用到双性人织物transglutaminase活动逐渐地增加了的阶段年轻圆锥花序发展并且直到在双性人的最大值的withtheprogression起核心作用在YuetaiA.However的舞台，没有类似的变化在YuetaiB被观察。这显示tissuetransglutaminase涉及房间在败育花粉的规划死亡。

简介：Objective:TostudytheprevalenceofTrichomonasvaginalis(TV)infectioninChinesemalepatientswithnongonococcalurethritis(NGU),toevaluatethesensitivityandspecificityofurine-basedandurethralswabpolymerasechainreaction(PCR)detection,tosetupamethodfornon-invasivedetectionofmaleTVinfection.Method:OnehundredandfivemaleNGUpatientswereselectedfromaBeijingSTDclinic.Twourethralswabswereobtainedfromeachpatient,onefortheInPouchTVculturesystemandtheotherforPCR.Inaddition,onefirstvoidurinespecimenwascollectedforPCRdetection.Culturewasconsideredthe“goldstandard”.Thesensitivity,specificity,positivepredictivevalue(PPV)andnegativepredictivevalue(NPV)ofthetwoPCRdetectionswerecomparedtocultureresults.Results:Theprevalenceofurine-basedPCRandurethralswabPCRdetectionwas3.81%(4/105)and4.76%(5/105)respectively.Comparedtoculture,thesensitivity,specificity,PPVandNPVwere80%,100%,100%and99%forurine-basedPCRand80%,99%,80%and99%forurethralswabPCR.Conclusion:TVisoneoftheetiologicalagentsinmaleNGU,witha4.76%prevalenceofinfectioninourstudy.TheurinebasedPCRdetectionhashighersensitivityandspecificityandprovidesanoninvasivemethodmorefeasibleinpractice.