简介:AbstractBackground:Endoscopic ultrasound (EUS)-guided transmural drainage for pancreatic fluid collections (PFCs) has become the first-line treatment with quicker recovery and more minor injury compared with surgery and percutaneous drainage. The efficacy of stents implantation and drainage for different PFCs remains controversial, especially lumen-apposing metal stents (LAMS). This study aimed to compare the efficacy and safety of LAMS drainage for pancreatic pseudocysts (PPC) and walled-off necrosis (WON).Methods:A meta-analysis was performed for LAMS drainage for WON and PPC by systematically searching PubMed, Cochrane, and Embase databases from January 2010 to January 2020. From 2017 to 2019, 12 patients who were treated with LAMS drainage for PFCs in our medical center were also reviewed and included in this study.Results:Combining 11 copies of documents with the data from our medical center, a total of 585 patients with PFCs were enrolled in this meta-analysis, including 343 patients with WON and 242 with PPC. The technical success rate in WON is not significantly different from that of PPC (P = 0.08 > 0.05). The clinical success of LAMS placement was achieved in 99% vs 89% in PPC and WON, respectively (RR = 0.92, 95% CI: 0.86-0.98, P = 0.01 < 0.05). The further intervention of direct endoscopic necrosectomy was required by 60% of patients in WON group. There was no significant difference in the incidence of adverse events, including infection, bleeding, stent migration and stent occlusion, after LAMS placement between WON and PPC.Conclusions:Endoscopic ultrasound-guided LAMS for PFCs are feasible, effective with preferable technical and clinical success rates. The clinical effect of LAMS on PPC is slightly better than that of WON, but its adverse reactions still need to be verified in a large-sample prospective study.
简介:※流明帮手2000流明帮手利用Windows操作系统提供您一个熟悉且容易使用的图形使用者接口。提供CAD接口一房间、对象(包括隔屏、桌子和椅子)与照明器具皆可使用鼠标作插入、移动、复制与删除之处理。三维立体检视画面提供您以卓越的视觉与设计操控能力,流明帮手循序渐进提示
简介:In2006ProfessorPatrickW.Serruysintroducedtheuseoffullybiodegradabledrug-elutingscaffolds.Thisnewstentwastoeliminatethepresenceofametalstentwhichwasapermanentmetallicforeignbodyinthecoronarycirculation.Thisrevolutionizedthethenfieldofinterventionalcardiology.
简介:AcompletemodelofMetal-Semiconductor-MetalPhotodetector(MSM-PD)ispresented.Itcanbeusedinanycircuitsimulators.SimulatedDCcharacteristicsforaGaAsMSM-PDareingoodagreementwithreportedresults.
简介:AbstractBackground:Sweat secreted by eccrine sweat glands is transported to the skin surface through the lumen. The eccrine sweat gland develops from the initial solid bud to the final gland structure with a lumen, but how the lumen is formed and the mechanism of lumen formation have not yet been fully elucidated. This study aimed to investigate the mechanism of lumen formation of eccrine gland organoids (EGOs).Methods:Human eccrine sweat glands were isolated from the skin for tissue culture, and the primary cultured cells were collected and cultured in Matrigel for 14 days in vitro. EGOs at different development days were collected for hematoxylin and eosin (H&E) staining to observe morphological changes and for immunofluorescence staining of proliferation marker Ki67, cellular motility marker filamentous actin (F-actin), and autophagy marker LC3B. Western blotting was used to detect the expression of Ki67, F-actin, and LC3B. Moreover, apoptosis was detected using a terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) apoptosis assay kit, and the expression of poly (ADP-ribose) polymerase and Caspase-3 was detected by Western blot. In addition, 3-methyladenine (3MA) was used as an autophagy inhibitor to detect whether the formation of sweat glands can be effectively inhibited.Results:The results showed that a single gland cell proliferated rapidly and formed EGOs on day 4. The earliest lumen formation was observed on day 6. From day 8 to day 14, the rate of lumen formation in EGOs increased significantly. The immunofluorescence and Western blot analyses showed that the expression of Ki67 gradually decreased with the increase in days, while the F-actin expression level did not change. Notably, the expression of autophagy marker LC3B was detected in the interior cells of EGOs as the apoptosis signal of EGOs was negative. Compared with the control group, the autophagy inhibitor 3MA can effectively limit the formation rate of the lumen and reduce the inner diameter of EGOs.Conclusion:Using our model of eccrine gland 3D-reconstruction in Matrigel, we determined that autophagy rather than apoptosis plays a role in the lumen formation of EGOs.
简介:AbstractBackground:To compare the safety and efficacy of LVIS stent-assisted coiling with those of laser-cut stent-assisted coiling for the treatment of acutely ruptured wide-necked intracranial aneurysms.Methods:Patients with acutely ruptured wide-necked intracranial aneurysms treated with LVIS stent-assisted coiling (LVIS stent group) and laser-cut stent-assisted coiling (laser-cut stent group) were retrospectively reviewed from January 2014 to December 2017. Propensity score matching was used to adjust for potential differences in age, sex, aneurysm location, aneurysm size, neck width, Hunt-Hess grade, and modified Fisher grade. Perioperative procedure-related complications and clinical and angiographic follow-up outcomes were compared. Univariate and multivariate analyses were performed to determine the associations between procedure-related complications and potential risk factors.Results:A total of 142 patients who underwent LVIS stent-assisted coiling and 93 patients who underwent laser-cut stent-assisted coiling were enrolled after 1:2 propensity score matching. The angiographic follow-up outcomes showed that the LVIS stent group had a slightly higher complete occlusion rate and lower recurrence rate than the laser-cut stent group (92.7% vs 80.6%; 3.7% vs 9.7%, P = 0.078). The clinical outcomes at discharge and follow-up between the two groups demonstrated no significant differences (P = 0.495 and P = 0.875, respectively). The rates of intraprocedural thrombosis, postprocedural thrombosis, postoperative early rebleeding, and procedure-related death were 0.7% (1/142), 1.4% (2/142), 2.8% (4/142), and 2.1% (3/142) in the LVIS stent group, respectively, and 4.3% (4/93), 2.2% (2/93), 1.1% (1/93), and 3.2% (3/93) in the laser-cut stent group, respectively (P = 0.082, 0.649, 0.651, and 0.683). Nevertheless, the rates of overall procedure-related complications and intraprocedural rupture in the LVIS stent group were significantly lower than those in the laser-cut stent group (5.6% vs 14.0%, P = 0.028; 0.7% vs 6.5%, P = 0.016). Multivariate analysis showed that laser-cut stent-assisted coiling was an independent predictor for overall procedurerelated complications (OR = 2.727, P = 0.037); a history of diabetes (OR = 7.275, P = 0.027) and other cerebrovascular diseases (OR = 8.083, P = 0.022) were independent predictors for ischemic complications, whereas none of the factors were predictors for hemorrhagic complications.Conclusions:Compared with laser-cut stent-assisted coiling, LVIS stent-assisted coiling for the treatment of acutely ruptured wide-necked intracranial aneurysms could reduce the rates of overall procedure-related complications and intraprocedural rupture.
简介:
简介:Au/Al_2O_3/Al金属/绝缘体/金属连接(MIMJ)和Au/SiO_2/Simetal/insulator/Si连接(MISJ)成功地被构造了。这些连接的轻排放被表面电浆子电磁声子(SPP)在表面粗糙下面调停。从MISJ的轻排放从MIMJ比那更一致、稳定。MISJ的轻力量比MIMJ的高是大约2份~3订单。MISJ的轻排放光谱特别被分析。在光谱,有一座主要山峰在610nm~6的波长定位了40nm,它主要由于有在Au/air和Au/SiO_2接口的表面粗糙的SPP的夫妇。在更短的波长区域位于光谱的一座弱山峰也被发现,它被doped-Si血浆摆动的直接放射引起。
简介:Alkalimetalhydroxideandhydridecompositesystemscontainbothprotic(HbondedwithO)andhydridichydrogen.Theinteractionofthesetwotypesofhydridesproduceshydrogen.Theenthalpyofdehydrogenationincreasedwiththeincreaseofatomicnumberofalkalimetals,i.e.,-23kJ/molH2forLiOH-LiH,55.34kJ/molH2forNaOH-NaHand222kJ/molH2forKOH-KH.Thesethermodynamiccalculationresultswereconsistentwithourexperimentalresults.H2wasreleasedfromLiOH-LiHsystemduringballmilling.ThedehydrogenationtemperatureofNaOH-NaHsystemwasabout150℃;whereasKOHandKHdidnotinteractwitheachotherduringtheheatingprocess.Instead,KHdecomposedbyitself.Inthesethreesystems,NaOH-NaHwastheonlyreversiblehydrogenstoragesystem,theenthalpyofdehydrogenationwasabout55.65kJ/molH2,andthecorrespondingentropywasca.101.23J/(molH2K),sothetemperatureforreleasing1.0barH2wasashighas518℃,showingunfavorablethermodynamicproperties.TheactivationenergyforhydrogendesorptionofNaOH-NaHwasfoundtobe57.87kJ/mol,showinggoodkineticproperties.
简介:冠的stents是通过导管送到堵住的容器的金属卷或网孔试管,它被汽球扩展再开并且支架目标容器。最近,特殊的药被stents(drug-elutingstents)带进一步在stenting过程以后减少in-stent狭窄率。然而,stents的biomechanical特征上的不断的学习为在stents和织物之间的更好的相互作用是必要的,或提供为drug-elutingstents装载站台的更合适的药。这份报纸的目的是显示出有限元素方法怎么能被用来学习弄弯的冠的stents的房间区域和神气分发变化。一样的弯曲变丑被用于冠的stent由一个僵硬弄弯的容器建模的二个广告。结果证明stent设计在把状况弄弯下面影响了房间区域和神气分发的变化。有连接的stent与山峰山峰在外部弯曲,和stent有更多的房间区域变化()神气设计能有神气接触并且在内部弯曲重叠。在结论,这个有限元素方法能被用来学习并且比较弄弯的stents的房间区域和神气分发变化,并且在新stents的严峻、改进的biomechanical特征为设计者提供一个方便工具。
简介:在自然,微生物涉及岩石捱过,在从矿物质的金属的动员,并且在金属降水和免职。这些微生物原则和过程能被改编对待微粒固体浪费。特别从金属珍视获得的稳固的矿物质(沥滤的称为的简历)的金属的微生物增溶是在采矿工业的一种著名技术。我们这里集中于非采矿矿物质浪费为包含金属的稳固的浪费的处理表明基于采矿的技术的适用性。从微粒苍蝇灰的在案例研究介绍的、微生物引起的金属动员(从市政的稳固的浪费焚化发源)而铅,铬,和镍被2,11和32%分别地动员,由Acidithiobacilli导致了>80%的镉,铜,和锌动员。另外,形成HCN细菌的潜力(Chromobacteriumviolaceum,Pseudomonasfluorescens)当面对稳固的材料成长时,被调查动员金属(例如,包含铜的矿石,电子碎片,花的汽车催化变换器)。C。violaceum从有细密纹理的镍粉末作为tetracyanonickelate动员镍被发现有能力。黄金是微生物引起地是的solubilized从电子废物的dicyanoaurate。另外,氰化物建筑群铜在切碎的打印电路板碎片的生物处理期间被检测。水溶性的铜和铂氰化物也在花的汽车的处理期间被检测催化变换器。
简介:UsingXenonlamplightstoovercomethestronginterferencefromtheweldingarc,acomputer-basedsystemisdevelopedtosenseandvisualizethemetaltransferinGMAW.Thissystemcombinesthrough-the-arcsensingoftheweldingcurrentandarcvoltagewithhighspeedimagingofthemetaltransfer.Itcansimultaneouslydisplaythemetaltransferprocessesandwaveformsofelectricalweldingparametersinreal-timeThemetaltransfervideosandwaveformsofelectricalweldingparameterscanberecorded.Metaltransfersundervariousweldingconditionshavebeeninvestigatedwiththesystemdeveloped.