简介：<正>TheUndergroundpalaceliesbeneaththeQintumulusandwasbuiltas"anundergroundheaven".Theundergroundpalaceisabout30metersbelowgroundlevelandhasdoorsfacingthefourdirections,fivedoorstotheeastandoneeachtothethreeothercompassdirections.

简介：ANancienttraditionstillobservedinChina'scountrysideisthehangingofelegantlydesignedcoupletsonhouseholdgatesonChineseNewYear'sEve.Whilemosthouseholdschangethesecoupletseveryyear,thoseinQin-

简介：TheYuandingshanMount圆顶山,located13kmtotheeastoftheseatoftheLixian礼县County,andtothesouthwestoftheZhaoping赵坪VillageofYongxing永兴Township,embracesacemeteryonitsnorthernslope,whichfacesthesouthernbankoftheYangshui漾水River.Thecemeterywaslootedinthebeginningof1998,andwasthenexcavatedbyacollaborativeteamfromtheGansuProvincialInstituteofAntiquityandArchaeologyandtheLixianCountyMuseumduringthefollowingmonthsofFebruarythroughJune.Threehumanburials(98LDKM1-M3)andonechariotburial(98LDK1)werethusexposed;thematerialispresentedbelow.

简介：MostoftheTsinghuaBambooSlips(TBS)textsdatefromtheWarringStatesperiodandtheyareeitherworksofthe(so-called)Classics(jing,經)orHistoricalbooks(shi,史).OneoftheTBStexts,whichfeaturesprominentlyinthecollectionasaparticularlywell-preservedpiece,isahistoricalworkin23chaptersand132bambooslips,whichhasbeenprovisionallytitledXinian繫年(‘Chronicles’).ThehistoricaleventsrecordedthereinrangefromtheperiodwhenKingWu(Wuwang,武王),thefounderoftheZhouDynasty,conqueredZhòu(紂)ofShang,totheearlyWarringStatesPeriod.TheeditedtextoftheXinianhasbeenpublishedinthesecondvolumeofthe‘BambooManuscriptsoftheWarringStatesPeriodintheTsinghuaUniversityCollection’(QinghuaDaxuecangZhanguozhujian清華大學藏戰國竹簡).1

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简介：Thec-JunN-terminalkinases(JNKs)areclassicstress-activatedproteinkinases.ManycellularstresseshavebeenshowntostimulateJNKactivation.Inthisreview,wefocusonribotoxicstressesbasedontheirmultiplebiologicalpotenciesincludinganti-HIV-1activity.Someofthefunctionsofribotoxinsandthesignalingtransductionpathwaythatmediatedarementioned.Differentfromotherstimulators,ribotoxicstressesactonspecialmotifsof28SrRNAintranslationallyactivemammalribosomes.BindinganddamagingonthemotifleadstoJNKactivationandsubsequentlybiologicalresponsetothesignalinitiator,whichisnamedribotoxicstressresponse.

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简介：ArtisticValue:YunZhongJunandDaSitilingwascreatedin1954.FuBaoshistartedpaintingfiguresafterhisrelocationtoSichuanProvinceinthe1930SlHewaslessprolificinthisgenrethaninlandscapes,butneverthelessdevelopedandretainedadistinctivestyle,ExtensivelyculturedinChinesehistoryanddassicaliterature,

简介：1.BirthofCALLNETinShanghai,Feb1984TimJohnsofBirminghamUniversityconductedaCALLworkshop,thefirstinChina,atShanghaiJiaotongUniversity.Itwentsowellthatthe24partic-ipants,mostlyEFLteachersfrom15universitiesandinstitutes,foundedanassociationCALLNETwithZhangYanbingandtheauthorascoordinatorsandTimasconsultant.TimbroughtthenewstotheChi-neseUniversity,HongKong,andHerbertPiersonjoinedin.

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简介：目的：观察小鼠不同程度缺氧适应对缺血缺氧脑即早基因c-fos和c-jun基因表达的影响。方法：采用链霉素亲生物素-过氧化酶(简称S-P)免疫组化技术。采用两种不同程度的缺氧预处理：①小鼠第一次缺氧开始到喘呼吸出现后，行第二次缺氧，定为B1组(此时瓶内的氧浓度为15％)；②小鼠第一次缺氧开始到瓶内的氧浓度降低为10％后，行第二次缺氧，定为B2组。结果：B2组的低氧存活时间明显长于B1组；缺血缺氧后30minc-fos和c-jun基因阳性细胞呈低密度分布，1hc-fos基因表达下降，12h则基本消失，阳性细胞呈散在分布。c-jun基因的表达高峰在缺血缺氧3h、12h时，c-jun基因阳性细胞仍呈低密度分布；缺氧适应使缺血缺氧脑增加的c-fos基因的阳性细胞数减少，而使缺血缺氧脑增加的c-jun基因的阳性细胞进一步增加，B1组和B2组缺血缺氧脑基因表达的影响无差异，结论：缺血缺氧可诱发中枢神经系统c-fos、c-jun基因表达．且有时间依赖性；缺氧适应可抑制缺血缺氧脑c-fos基因的表达，增强缺血缺氧脑c-jun基因的表达。

简介：I.TheproblemoftherelationshipofliandfainancientChineselawBecauseofdifferencesinculture,anindependentlawsystem,theChineseLawSystem,cameintobeingwithitsdifferencesfromotherlawsystemsoftheworld,whicharerepresentedbytheContinentalLawSystem(alsoknownastheCodeLawSystem)andAnglo-AmericanLawSystem(alsoknownasthe

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简介：摘要目的探讨Rho激酶抑制剂盐酸法舒地尔(fasudil)对核转录因子c-jun磷酸化和蛋白表达的影响。方法采用四动脉结扎大鼠全脑缺血模型，分为假手术组、缺血/复灌组、生理盐水对照组和盐酸法舒地尔组，缺血前30分钟腹腔给药，选择c-jun磷酸化高峰的时间点，即缺血/复灌6小时断头、取海马CA1区、匀浆、提核、测蛋白，采用免疫印迹方法，检测c-jun磷酸化和蛋白的表达。结果盐酸法舒地尔组c-jun磷酸化水平显著低于缺血/复灌组及生理盐水对照组（P＜0.05），对照组与缺血/复灌组之间差异无显著性（P＞0.05），而对这一时间点的蛋白表达水平无明显影响。结论盐酸法舒地尔可抑制大鼠缺血/复灌诱导的

简介：目的探索急性脊髓损伤后大鼠脊髓组织中c-Jun氨基末端激酶（c-Junamino-terminalkinase,JNK)基因表达与神经功能修复状态的关联。方法取健康成年雄性大鼠50只，随机选取，假手术对照组18只，实验组32只。损伤后1、12、24、72h行PCR检测，比较大鼠脊髓组织中JNK(JNK1、JNK2、JNK3)表达水平变化；损伤后12、72h选取L4/5节段脊髓行HE染色、，比较脊髓损伤大鼠脊髓组织细胞凋亡情况、神经功能变化状态(NSSh结果PCR结果显示，髓损伤大鼠脊髓组织中JNK1、JNK2、JNK3的表达，在损伤后1、12、24、72h除JNK3在相应时点表达水平与假手术组比较水平下降外，其他两项表达与假手术对照组无明显差别。L4/5脊髓HE染色结果提示，与假手术组比较，损伤后12h损伤的脊髓皮质周边EHE染色阳性细胞显著增多。随着时间推移，染色阳性细胞出现明显减少的趋势，损伤后12h的染色阳性细胞明显少于72纪损伤组NSS评分则明显更高，但脊髓损伤组损伤后不同时点比较，NSS评分渐减。结论脊髓损伤后出现JNK3表达下调的情况，可能与神经细胞凋亡以及促进损伤后神经功能的恢复有关联。