简介:【摘要】目的:分析Bio-gide膜材料用于牙种植引导骨再生(GBR)的效果。方法:将本院2021年6月至2023年1月进行牙种植术的76例患者纳入研究对象,均分为2组,即实验组和对照组,每组38例,实验组患者在牙种植GBR中使用Bio-gide膜材料,对照组患者则使用海奥口腔修复膜,比较不同膜材料的应用效果。结果:两组患者术后6个月的水平与垂直骨生长率、植骨高度和厚度对比,实验组水平更高(P<0.05);实验组患者的种植成功率明显高于对照组,并发症总发生率低于对照组(P<0.05)。结论:Bio-gide膜材料用于牙种植GBR的效果较好,可促进骨生长,减少并发症,并提升种植成功率。
简介:Objective:Tostudytheeffectofbio-derivedbones,assubstitutesofautogenousbonegraftsanddemineralizedcadaverbones,ontheattachment,spreadingandproliferationofisolatedosteoblasts.Methods:Osteoblastswereisolatedfromthecalvariaofafetalrabbitthroughsequentialcollagenasedigestion.Intheattachmentstudy,theosteoblastslabeledwith3H-leucinewereincubatedwiththebio-derivedbonematerialsinsterilemicrocentrifugaletubesfor15,90and180minutes,and24hours,respectively.Theattachedcellswerecollectedandtheradioactivitywasmeasuredwithliquidscintillationspectrometry.Intheproliferationstudy,theosteoblastswereculturedwiththebio-derivedbonematerialsfor24hoursand3H-thymidinewasaddedduringthelast2hoursoftheincubation.Theattachedcellswerecollectedandtheradioactivitywasmeasuredwithliquidscintillationspectrometry.Osteoblastswereseededonthebonegraftmaterialsfor60or120minutes,24or48hours,and3or7days,thentheco-culturewasprocessedforscanningelectronmicroscopytoobservetheinteractionofosteoblastsandthebio-derivedbonematerials.Results:Osteoblastsattachedtothebio-derivedbonematerialsinatime-dependentmanner.Thereweresignificantly(P<0.05)moreattachedcellsafter180minutesthanafter15and90minutesofincubations(P<0.05).Osteoblastswereproliferatedinalargeamountonthesurfaceandinthematerials.Osteoblastsseededonto100mgbio-derivedbonesresultedinsignificantly(P<0.05)moremeasurableproliferationthanthoseseededonto10mgbones.Osteoblastsappearedroundastheyattachedtothematerials,thenflattenedandspreadoverwithtimepassing.Conclusions:Bio-derivedbonescanprovideagoodenvironmentfortheattachmentandproliferationofosteoblasts.
简介:摘要目的探讨Bio-Oss联合Bio_GidePerio在修复牙槽突裂的临床护理。方法对我院2013年6月~2014年4月为20例齿槽突裂患者应用Bio-OssR天然骨无机材料及Bio-GideRPerio胶原膜修复齿槽突裂手术的护理总结。结果因护理措施得当,20例患者采用Bio-GideR修复牙槽突裂,术后观察,其中19例患者术后伤口均获一期愈合,口鼻瘘得以严密关闭。1例腭侧黏膜未愈合,局部涂擦盐酸米诺环素后伤口愈合良好1。结论Bio-OssR联合Bio-GideRPerio修复牙槽突裂具有良好的生物相容性,多孔状结构能为新骨生长提供良好的空间支架,对增强上颌骨的稳定性和连续性,改善牙槽嵴的高度和外形起重要作用2。而Bio-GideR骨膜是一种较低的抗原性和出色的生物相容性胶原膜,在牙槽突缺损部位具有引导组织再生功能及膜屏障和骨修复的双重作用,Bio-OssR联合Bio-GideRPerio更有利于牙槽突裂的骨再生及颌骨重建3。
简介:Thefieldofmechanicsofbiologicalandbio-inspiredmaterialsunderwentanexcitingdevelopmentoverthepastseveralyears,whichmadeitstandatthecuttingedgeofbothengineeringmechanicsandbiomechanics.Asanintriguinginterdisciplinaryresearchfield,itaimsatelucidatingthefundamentalprinciplesinnature'sdesignofstrong,multi-functionalandsmartMaterialsbyfocusingontheassembly,deformation,stabilityandfailureofthematerials.Theseprinciplesshouldhavewideapplicationsinnotonlymaterialsciencesandmechanicalengineeringbutalsobiomedicalengineering.Forinstance,theknowledgeinMechanicalprinciplesofbiologicalmaterialsisveryhelpfulforaddressingsomemajorchallengesinmaterialsciencesandengineering.Theyalsohavethepotentialtoprovidequantitativeunderstandingabouthowforcesanddeformationaffecthumanbeing'shealth,diseasesandtreatmentattissue,cellularandmolecularlevels.
简介:Instrongsolarlight,siliconsolarpanelscanheatupby70℃and,thereby,looseapproximatelyonethirdoftheirefficiencyforelectricitygeneration.Leafstructuresofplantsontheotherhand,havedevelopedaseriesoftechnologicaladaptations,whichallowthemtolimittheirtemperatureto40-45℃infullsunlight,evenifwaterevaporationissuppressed.Thisisaccomplishedbyseveralstrategiessuchaslimitationofleafsize,optimizationofaerodynamicsinwind,limitationofabsorbedsolarenergyonlytotheusefulfractionofradiationandbyefficientthermalemission.Opticalandinfraredthermographicmeasurementsunderasolarsimulatorandinastreamingchannelwereusedtoinvestigatethecorrespondingpropertiesofleavesandtoidentifysuitablebionicmodelsystems.ExperimentsstartedwiththeserratedstructureofordinarygreenleavesdistributedovertypicaltwigstructuresandfinallyidentifiedtheAustralianpalmtreeLicualaramsayiasamoreusefulbionicmodel.Itcombinesalargeareaforsolarenergyharvestingwithoptimizedaerodynamicpropertiesforcoolingandisabletorestructureitselfasaprotectionagainststrongwinds.Thebionicmodels,whichwereconstructedandbuilt,areanalyzedanddiscussed.
简介:Cellularmetabolismisaverycomplexprocess.Thebiochemicalpathwaysarefundamentalstructuresofbiology.Thesepathwayspossessanumberofregenerationstepswhichfacilitateenergyshuttlingonamassivescale.Thisfacilitatesthebio-chemicalpathwaystosustaintheenergycurrencyofthecells.Thisconcepthasbeenmimickedusingelectroniccircuitcom-ponentsandithasbeenusedtoincreasetheefficiencyofbio-energygeneration.Sixofthecarbohydratebiochemicalpathwayshavebeenchoseninwhichglycolysisistheprinciplepathway.Allthesixpathwaysareinterrelatedandcoordinatedinacom-plexmanner.Mimiccircuitshavebeendesignedforallthesixbiochemicalpathways.Thecomponentsofthemetabolicpath-wayssuchasenzymes,cofactorsetc.,aresubstitutedbyappropriateelectroniccircuitcomponents.Enzymesarerelatedtothegainoftransistorsbythebonddissociationenergiesofenzyme-substratemoleculesunderconsideration.Cofactorsandcoen-zymesarerepresentedbyswitchesandcapacitorsrespectively.Resistorsareusedforproperorientationofthecircuits.Theenergyobtainedfromthecurrentmethodsemployedforthedecompositionoforganicmatterisusedtotriggerthemimiccir-cuits.Asimilarenergyshuttleisobservedinthemimiccircuitsandthepercentageriseforeachcycleofcircuitfunctioningisfoundtobe78.90.Thetheoreticalcalculationshavebeenmadeusingasampleofdomesticwasteweighing1.182kg.Thecalculationsarrivedatfinallyspeakoftheefficiencyofthenovelmethodologyemployed.
简介:WeintroducetherelationshipbetweenexcessnoiseinOptoelectronicCoupledDevices(OCDs)andtheirinteriordefectsandexplainhowlow-fiequencynoisecanbeusedtoestimatetheirreliability.Usingconceptsfromthebiologicalimmunesystemanditsprocessofidentifyinginvaders,wepresentasystemforestimationofthereliabilityofOCDs.Thesystemhasexpressionsfortheantigen(excessnoise),lymphocyte(criterion)andtheroleofthelymphocyteeliminatingunreliabledevices.AgeneticalgorithmwasusedtoestimatethecomponentsparametersofthenoisespectrumforestimatingthereliabilityofOCDs.Theexperimentalresultsdemonstratedthatthismethodisreliable,adaptableandpractical.
简介:PresentlytheironandsteelmakersarecompelledtoincorporaterationalinitiativestoreduceitsprocessingCO2totalemissions.Inthemediumandlongterm,theinjectionofsmallparticlesofbiocharthroughthetuyereesinblastfurnaces,herecalledBio-PCI,offersattractivefeaturesfromtheenvironmentalandmetallurgicalpointofview,asitisarenewablecarbonneutralreductantandpresentslesserimpuritiesthancoke.However,itsutilizationinironplantsisbeenhinderedbythetraditionallargeavailabilityofrelativelyeconomicalcoalandcoke.Asthecostoftheprincipalprocessinginputsincreases(coal,cokeandironore)thegapbetweenfossilandrenewablereductantsdecreases.Inthissense,ourcontributionaimstocomplementthemetallurgicalinquiryoftechnicalfeasibilitywithastrategicidentificationoftheareaswithbestprospectstobenefitsfromtheincorporationofBio-PCI:wherecanitflourish?.Ouranalysisleadstoindicatethatemergingcountriesinspecific,China,BrazilandIndia,areinaprimepositiontoincorporatetheBio-PCIastheysimultaneouslycomplywithagrowingironindustrybasedonblastfurnaces,andpossessanimportantpotentialforenergygenerationfromforestryresidues.
简介:Asystemisdescribedherethatcannoninvasivelycontrolthenavigationoffreelybehavingratviaultrasonic,epidermalandLEDphoticstimulatorsontheback.Thesystemreceivescommandsfromaremotehostcomputertodeliverspecifiedelectricalstimulationstothehearing,painandvisualsensesoftheratrespectively.Theresultsdemonstratethatthethreestimuliworkingroupsfortheratnavigation.Wecancontroltherattoproceedandmakerightandleftturnswithgreatefficiency.Thisexperimentverifiedthattheratwasabletoreachasettingdestinationinthewayofcablewiththehelpofapersonthroughtheappropriatecoordinationofthethreestimulators.Thetelemetryvideocameramountedontheheadoftheratalsoachieveddistantimageacquisitionandhelpedtoadjustitsnavigationpathoveradistanceof300m.Inaword,thenon-invasivemotioncontrolnavigationsystemisagood,stableandreliablebio-robot.
简介:Thispaperpresentsthedesign,fabrication,andexperimentalcharacterizationofaperistalticmicropump.ThemicropumpiscomposedoftwolayersfabricatedfromPolydimethylsiloxane(PDMS)material.Thefirstlayerhasarectangularchannelandtwovalveseals.Threerectangularminilightweightpiezo-compositeactuatorsareintegratedinthesecondlayer,andusedasactuationparts.Twolayersarebonded,andcoveredbytwoPolymethylMethacrylate(PMMA)plates,whichhelpincreasethestiffnessofthemicropump.Amaximumflowrateof900μL·min-1andamaximumbackpressureof1.8kPaarerecordedwhenwaterisusedaspumpliquid.Wemeasuredthepowerconsumptionofthemicropump.Themicropumpisfoundtobeaprom-isingcandidateforbio-medicalapplicationduetoitsbio-compatibility,portability,bidirectionality,andsimpleeffectivedesign.
简介:Natureinspiredsolutionsenablebiologicalsystemstoadaptandaccomplishtheirtasksinverynoisyanduncertainenvironments.Takinginspirationfromnature,anovelbacteriacontrollercapableoffindingthesourceofpollutioninanunderwatermediumturbulentenvironmentispresentedinthispaper.Experimentsprovethatthecontrolleriscapableofperformingpollutionsourceexploration,pollutionplumetransverseandsourcedeclarationinamediumPecletenvironmentwithoutdistinctivelyseparatingthesethreecomponentsasmostresearchersdid.Theresultsobtainedfromtheseexperimentsareconsideredasasteptowardsthedeploymentofroboticfishinahighlyturbulentmarineenvironment.Finally,abriefconclusionandfutureextensionarepresented.