简介: 我服兵役那几年,牛排长很以自己的大尿泡而傲视群雄.三连的兵们私下议论,牛排长撒尿的架势都像个将军哩!副指导员田林听见了,不以为然地扑哧道,别糟踏将军了!他牛啥牛?就凭他的膀胱比别人大一号?最多,那也只能算是个比较特殊的生理现象.……
简介:摘要目的对前列地尔与缬沙坦联合用于早期糖尿病肾病的临床疗效加以探讨.方法选取2014年2月至2015年6月来我院内分泌科就诊的糖尿病肾病患者76例,将其随机分为观察组与对照组各38例.对照组病例予以前列地尔治疗,观察组病例则予以前列地尔与缬沙坦联合治疗,两组病例均进行为期8周的治疗.将两组病例治疗总有效率及不良反应发生率加以比对.结果观察组38例患者中,治疗有效为31例(81.6%);显著高于对照组的23例(60.5%),组间比较差异显著,有统计学意义(P<0.05).结论将前列地尔与缬沙坦联合用于早期糖尿病肾病的临床治疗可有效提高治疗总有效率,且其不良反应发生率未有增加,可于临床中推广应用.关键词前列地尔;缬沙坦;糖尿病肾病;联合治疗Abstractobjectivetoinvestigatetheclinicalefficacyofalprostadilcombinedwithvalsartancombinedforearlydiabeticnephropathyandanalysis.MethodsChoosefromFebruary2014toJune2015toourhospitalfortreatmentofendocrineclinicpatientswithdiabeticnephropathy76caseswererandomlydividedintoobservationgroupandcontrolgroup38cases.Thecontrolgroupofpatientstobealprostadiltreatment,observationgroupofpatientsistobealprostadilwithcomGbinationtherapywithvalsartan,twocaseswereforaperiodofeightweeksoftreatment.Thetotalefficiencyoftwogroupsofpatients,andtheincidenceofadGversereactionsarecompared.Results38patientsintheobservationgroup,atherapeuticallyeffectiveforthe31cases(81.6%);significantlyhigherthanthe23cases(60.5%),asignificantdifferencebetweenthetwogroupswasstatisticallysignificant(P<0.05);ConclusionTheclinicaltreatmentwillalprostadilusedincombinationwithvalsartanearlydiabeticnephropathytreatmentcaneffectivelyimprovetheoverallefficiency,andtheincreasedincidenceofadversereactionsnotbeincKlienyicwaloradpsplication.Alprostadil;Valsartan;Diabeticnephropathy;Combinationtherapy中图分类号R587.2文献标识码B文章编号1008-6315(2015)12-0382-01