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简介:摘要:本文以再现系统为例,从部件原理,到系统功能设计,深入浅出的阐述功能设计到实现的过程。让从业者更了解系统。
简介:Inthispaper,firstlywedemonstratetheuseofnodaladmittancematrixtoconvertalow-passband-passfilterbasedonoperationalamplifier(op-amp)toacircuitbasedonasecond-generationcurrentconveyor(CCII).Thistechniqueallowsustogeteightpresumptionsoffiltercircuits.Secondly,wepresentanovelarchitecturecircuitofCCII,whichcanoperateatlowsupplyvoltageof±0.75V.AllsimulationsareperformedbyTSPICEmodels.ThesimulationresultsshowthatthiscircuithasalowimpedanceatterminalX(RX=1.01Ω),averyhighinputimpedanceatterminalY,andwidebandwidthcurrentandvoltage.Thecenterfrequencyoftheproposedfilterisvariableontheinterval[157kHz,196MHz].
简介:AbstractTrauma during pregnancy deserves special attention because of its management objectives, i.e. wellbeing of both pregnant woman and foetus. Maxillofacial trauma directly affects the nutrition of foetus by interfering with the normal functions in a pregnant woman such as mouth opening, mastication and breathing. Hence early restitution of form and function of maxillofacial skeleton is essential. However, the gravid status is associated with numerous anatomical and physiological changes which present with clinical dilemma related to imaging and treatment. A careful scrutiny of the patient's systemic and gestational status is absolutely essential before, during and after instituting any interventional procedures. We present a case of bilateral condyle fracture in a 30-year-old pregnant woman in the third trimester (32 weeks). She was treated with inter maxillary fixation using orthodontic brackets & elastics. After successful restitution of occlusion, the patient was advised aggressive physiotherapy which ensured normal mouth opening. Two weeks later, the patient delivered uneventfully. The patient was followed up at one month and 3 month and demonstrated restitution of normal occlusion, mouth opening and lower facial height. This article aims at analyzing the contemporary principles in management of maxillofacial trauma in a pregnant woman and clarifying the common misconceptions.
简介:cAMPsignalingandthecontrolofSchwanncellfate:Theubiquitoussecondmessengercyclicadenosinemonophosphate(cAMP)controlsavarietyofcellularresponsesinacelltype-specificandstimulus-dependentmannerthroughanelaboratenetworkofsignalingintermediariesthatconnectstimulationofcellmembranereceptors(typicallyG
简介:(QS)治安法官察觉到是细菌用称为autoinducers的细胞外的信号由交流的细菌的房间房间通讯进程。二个QS系统在EscherichiacoliK-12被识别了,包括一个未经触动的QS系统2那被周期的安培(营地)营地受体蛋白质(CRP)刺激建筑群和一个部分QS系统1那由对另外的微生物引起的种类产生的信号作出回应的SdiA(房间部门禁止者的suppressor)组成。在QS之间的关系在E的系统1和系统2。然而,coli仍然保持阴暗。这里,我们显示出那EAL域蛋白质,由ydiV,和营地编码了在E涉及在二个QS系统之间的相互作用。coli。sdiA和ydiV的表示被葡萄糖禁止。SdiA在一个剂量依赖者,而是nonspecific绑在ydiV倡导者区域,举止;细胞外的autoinducer1以一种sdiA依赖的方式从另外的种类刺激ydiV表示。而且,我们发现双sdiA-ydiV变化,然而并非单个变化,在导致QS系统2的抑制的细胞内部的营地集中引起2褶层减少。这些结果显示对重要环境暗示作出回应的发信号的小径例如autoinducers和葡萄糖,在E为他们的控制一起被连接。coli。
简介:目的Coptidis根茎(CR),亚洲植物(包括的黄连属chinensisFranch)的弄干的根茎,被用来对待糖尿病mellitus几千年。我们探索了CR在骨胳的肌肉上直接扮演的可能性,为葡萄糖动态平衡负责的主要机关,并且激活5-AMP-activated蛋白质kinase(AMPK),导致骨胳的肌肉的新陈代谢的改进的一个发信号的中间人。孤立的老鼠epitrochlearis和soleus肌肉在包含一篇CR水摘录(CE)的一个缓冲区被孵化的方法,和AMPK和相关事件的激活被检验。响应CE治疗的结果,在AMPK的催化子单元的Thr172的phosphorylation,为完整的kinase激活的必要的步,在两肌肉增加了。乙酰CoAcarboxylase(ACC)的Ser79的Phosphorylation,AMPK的内长的底层,附随地增加了。isoform特定的AMPK活动的分析表明CE两个都激活催化子单元的1和2isoforms。重要地,AMPKphosphorylation上的CE的最大的效果比berberine(BBR)的显著地大,显示CE的行动完全没被归功于到BBR。我们建议那CE的结论是在快抽动、慢抽动的骨胳的肌肉的AMPK的尖锐使活跃之物。