简介：Toconfirmtheexistenceandpropertiesofhumanmeridians,theopticaltransportpropertiesalongthepericardiummeridianandtissuesaroundthepericardiummeridianarestudiednoninvasivelyontwentyhealthyvolunteersinvivoandthencomparedwitheachother.Ourstudyshowsthatthelightpropagatingalongthemeridianandnon-meridiandirectionsbothconformtotheBeer’sexponentialattenuationlaw.However,statisticalanalysisoftheresultssuggeststhattheopticaltransportpropertiesofhumanmeridiandifferfromthoseofthesurroundingtissuesoveralowmodulatedfrequencyrange(P<0.01),andlightattenuationalongthepericardiummeridianissignificantlylessthanthatalongthenon-meridiandirection.Thesefindingsnotonlyindicatetheexistenceofacupuncturemeridianfromthepointofviewofbiomedicaloptics,butalsoshednewlightonanapproachtoinvestigationofhumanmeridians.更多还原

简介：Steadystateandtime-resolvedautofluorescencespectroscopiesareemployedtostudytheautofluorescencecharacteristicsofhumancolonictissuesinvitro.Theexcitationwavelengthvariesfrom260to540nm,andthecorrespondingfluorescenceemissionspectraareacquiredfrom280to800nm.Significantdifferenceinfluorescenceintensityofexcitation-emissionmatrices(EEMs)isobservedbetweennormalandtumorcolonictissues.Comparedwithnormalcolonictissue,lownicotinamideadeninedinucleotide(phosphate)(NAD(P)H)andflavinadeninedinucleotide(FAD),andhighaminoacidsandprotoporphyrinIX(PpIX)fluorescencescharacterizehigh-grademalignanttissue.Moreover,theautofluorescencelifetimesofnormalandcarcinomatouscolonictissuesat635nmunder397-nmexcitationareabout4.32±0.12and18.45±0.05ns,respectively.ThehighaccumulationofendogenousPpIXincoloniccancersisdemonstratedinbothsteadystateandtime-resolvedautofluorescencespectroscopies.更多还原

简介：Aspatialdistributionofdiffusereflectanceproducedbyobliquelyincidentlightisnotcenteredaboutthepointoflightentry.Thevalueofshiftinthecenterofdiffusereflectanceisdirectlyrelatedtotheabsorptioncoefficientμ_aandtheeffectiveattenuationcoefficientμ_(eff).μ_aandthereducedscatteringcoefficientμ'_sofhumanskintissuesinvivoaremeasuredbyoblique-incidencereflectometrybasedonthetwo-sourcediffusetheorymodel.FortenChinesevolunteersaged15-63years,μ_aandμ'_sarenoninvasivelydeterminedtobe0.029-0.075and0.52-0.97mm~(-1),respectively.