简介：AIM:TodeterminethevisualoutcomesinadultpatientswhosustainedopenglobeinjuriesandtodeterminewhetherthevisualprognosisfollowinganeyeinjuryinanAfricansettingdiffersfromthepredictedoutcomesaccordingtotheOcularTraumaScore(OTS)study.AsecondaryaimwastoestablishtheeviscerationratefortheseinjuriesandassesshowthisformofinterventionaffectedoutcomesincomparisontotheOTS.·METHODS:Aprospectivecaseseriesofallpatientsadmittedwithopenglobeinjuriesoveratwo-year(July2009toJune2011)period.InjurieswerescoredusingtheOTSandthesurgicalinterventionwasrecorded.Thebestcorrectedvisualacuityatthreemonthswasregardedasvisualoutcome.·RESULTS:Therewere249openglobeinjuries,ofwhich169patients(169eyes)completedthe3-monthfollow-up.Allpatientsunderwentprimarysurgery,175(70.3%)repairs,61(24.5%)eviscerationsand13(5.2%)otherprocedures.GlobeeviscerationsweremainlydoneonOTSCategory1cases,butoutcomesinthiscategorywerenotfoundtobedifferentfromOTSoutcomes.OutcomesweresignificantlyworseinCategory2,butwhentheentiredistributionwastested,thedifferenceswerenotstatisticallysignificant.TheoverallassociationbetweenOTSoutcomesandthefinalvisualoutcomesinthisstudywasfoundtobeastrong(P<0.005).·CONCLUSION:Reliableinformationregardingtheexpectedoutcomesofeyeinjurieswillinfluencemanagementdecisionsandpatientexpectations.TheOTSisavaluabletool,theuseofwhichhasbeenvalidatedinmanypartsoftheworld-itmayalsobeavalidpredictorinanAfricansetting.

简介：AIM:ToinvestigatetheepidemiologiccharacteristicsandoutcomesofopenglobeinjuryinShanghai.METHODS:Aretrospectivestudywasconductedfor148unilateralopenglobeinjurycasespresentingtoatertiaryreferralhospitalofShanghai.Electronicmedicalrecordswerereviewedandphonesurveyswereconductedtocollectandanalyze1)backgroundofpatient;2)settingofinjuryandclinicalsignsatpresentation;3)treatmentprocedureandoutcome;4)qualityoflifeafterinjury.RESULTS:Thereweremoremalepatients(77.03%)thanfemales(22.97%),moretemporaryhabitants(79.05%)thanresidents(20.95%).ThesubjectsinthisstudypresentedasignificantlylowerconstitutionalstatusofeducationthanthatofthewholeShanghaipopulation(P<0.001).Occupationalinjurywasthefirstcauseofinjuries(39.86%),followedbyhomeaccident(20.27%),roadaccident(16.89%),violentbehavior(16.89%)andoutdoorinjury(6.08%).The143subjects(96.62%)werenotwearingspectaclesatthetimeofinjury.Ofallpatients,77subjects(52.03%)hadtheoutcomeofnovision(includingenucleation).Theclassificationandregressiontree(CART)prognosispresents59.58%sensitivitytopredictvisualsurvivalcorrectlyand80.19%specificitytopredictnovisioncorrectly.Thepatientswhoseinjuredeyehadnovisionreportedmorereductionoflifequality.CONCLUSION:Wefoundthatmalesubject,temporaryhabitants,loweducationalstatusandnoeyewearareriskfactorsofopenglobeinjuryinShanghai.Occupationalinjuryistheleadingcause.CARTanalysispresentsacertainagreementtotheactualvisualoutcome.Theinjuryimposesnegativeimpactonqualityoflifeespeciallyinnovisioncases.Theeducationofeyeprotectionmayhelptoavoidtheinjury.

简介：AIM:ToevaluatetheoutcomesofAhmedglaucomavalve(AGV)implantationsurgeryforrefractoryglaucoma.METHODS:Thisone-armedhistoricalcohortstudywasconductedin2011.Refractoryglaucomawasdefinedaseyeswithanintraocularpressure(IOP)greaterthan21mmHgwithmaximallytoleratedglaucomamedications,failedsurgeries,orboth.ForalleyeswithrefractoryglaucomathatunderwentAGVimplantation,datawerecollectedonIOP,thebestcorrectedvisualacuity(BCVA)andglaucomamedicationspreoperativelyand4,6,12,24and56wkpostoperatively.LogarithmvaluesofIOPwerecalculatedandcompared.RESULTS:Thestudygroupwascomprisedof30patients(30eyes,16malesand14females)withrefractoryglaucoma.MeanpreoperativeIOPwas39.3±13.8mmHg.PostoperativemeanIOPwas15.7±7.1mmHg,19.6±12.8mmHgand13.9±14.2mmHgat12,24and56wkrespectively.BCVAwas≥6/60in11eyespreoperatively,andfiveeyeshadBCVA≥6/60at56wkpostoperatively.Preoperatively,morethanfourmedicationswereusedtotreatglaucomain21eyes.At12wkpostoperatively,nomedicationswererequiredtocontrolIOPin20eyes.At56wkpostoperatively,atleastonemedicationwasrequiredtocontrolIOPin10eyes.Overtheentirefollowupperiod,foureyesweretreatedwithyttriumaluminiumgarnet(YAG)laserand14eyesrequiredasecondsurgery.TheAGVwasremovedinfoureyes.CONCLUSION:AGVimplantationreducedIOPandthenumberofmedicationsrequiredtocontrolrefractoryglaucoma.However,therewasahigherriskofdecreasedvision.Long-termfollowupandpromptinterventionarerecommended.

简介：AIMTo评估安全和27计量器(27G)的功效侧面为有跟随27GPPV的各种各样的vitreoretinal疾病的61只眼睛(58个病人)的临床的结果是的各种各样的vitreoretinaldiseases.METHODSThe的治疗的同等planavitrectomy(PPV)回顾地，reviewed.RESULTSSurgical指示包括了rhegmatogenous网膜的分开(n=24)，完整厚度的有斑点的洞(n=12)，糖尿病的retinopathy(n=11)，玻璃的出血(n=6)，Eales疾病(n=4)，病理学近视相关玻璃吝啬的后续是166.4牵敧祲刮卅?協桔???????????????挠灡?潬潴祭?????????????????????????浥瑡硯汹湩攭獯湩?€浩畭潮汦潵敲'諟Ｉ????????吗?????????????？？

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简介：AIM:Todeterminethelong-termeffectsofselectivelasertrabeculoplasty(SLT)onintraocularpressure(IOP)andthenumberofmedicationsusedupto5yfollowingtreatmentinglaucomapatientsreceivingmaximallytoleratedmedicaltherapy(MTMT).·METHODS:TheWillsEyeHospitalGlaucomaResearchCenterretrospectivelyreviewedthechartsofglaucomapatientswhounderwentSLTafterreceivingMTMT.Eyesthatdidnotachievetheirtargetpressurewithin3mofollowingSLTwereexcludedfromthestudy.ChangesinmeanIOPandnumberofglaucomamedicationsusedwereanalyzedat1,3,and5yfollowingSLT.·RESULTS:Seventy-fiveeyesof67patientswereincludedinthestudy.FifteeneyesthatreceivedSLTfailedtoachievetheirtargetpressurewithin3moandwereexcludedfromthestudy.Theaveragefollow-uptimewas37.4mo(±14.4).MeanIOPwassignificantlyreduced1yaftertreatment(P=0.005).Itwasalsoreduced3,5yaftertreatmentwithoutreachingstatisticalsignificance(P=0.20andP=0.072,respectively).Therewasasignificantdecreaseinmeannumberofmedicationsused1,3,5yaftertreatment(P<0.001,P<0.001,andP=0.039,respectively).Inthespanof5y,2eyes(2.7%)underwentrepeatSLT,7eyes(9.3%)underwentglaucomasurgeryandanadditional3eyes(4.0%)underwentboth.·CONCLUSION:SLTsignificantlyreducedthenumberofglaucomamedicationsused5yfollowingtreatmentinglaucomapatientsreceivingMTMT.SLTmaydelayoperating-roomsurgery.

简介：AIMTo与医学上在开的角度绿内障(OAG)或在医药treatment.METHODSThis学习是的antiglaucoma下面是主要或第二等的OAG病人的回顾的评论的眼睛的高血压(OHT)病人和OHT病人作为附属治疗估计有图案的激光trabeculoplasty(PLT)的功效和安全不受管束(18公里Hg)intraocular压力(IOP)谁经历了360浥湡？

简介：AIMTo评估剥去与在没有胶囊的support.METHODSDSAEK的严重地损坏的眼睛的透镜(IOL)培植与工匠虹爪IOL培植相结合的工匠缺少晶状体intraocular相结合的自动化endothelialkeratoplasty(DSAEK)的descemet的复杂并发症和结果在29只眼睛上被执行。所有眼睛由于从优先的intraocular手术和眼睛的损伤的复杂并发症具有反常结构。眼睛的复杂并发症观察了包括的接枝脱臼，高intraocular压力(IOP)，IOL脱臼，有斑点的浮肿和hyphema。最好改正的视觉尖酸(BCVA)，IOP和吝啬的中央endothelial房间密度(ECD)是有的recorded.RESULTSThirteen眼睛眼睛的损伤的历史，10只眼睛有前面的房间IOL，16只眼睛有优先的vitrectomy。虹在22种情况中是反常的。接枝脱臼发生在5(17.2%)29只眼睛。IOL脱臼发生在2只眼睛(6.9%)。高IOP在9只眼睛被发现并且与处理被控制。外科手术前的吝啬的BCVA是20/286。6mo手术后的吝啬的BCVA是20/42。平均中心ECD是在6mo的1965.3房间/公里2，并且施主房间损失的率是与工匠缺少晶状体IOL培植相结合的34.7%.CONCLUSIONDSAEK是为没有胶囊的支持，在aphakic眼睛解决endothelial和透镜混乱的一种其他的选择。然而，它应该与严重的虹缺点为眼睛小心地被执行。

简介：这研究在跟随加速的transepithelial的keratoconus角膜评估了临床的结果角膜的骨胶原cross-linking(CXL)(AvedroKXL?系统，麻省沃尔瑟姆，美国)超过一年后续。光连贯断层摄影术(10月)测量的分界线的吝啬的深度是205.19???吳????????<

简介：第二等的绿内障的长期的结果在回顾的学习包括了的一系列中国patients.METHODSThe与Ahmed绿内障阀门(AGV)由于眼色素层炎对待培植的AIMTo报告从经历了AGV培植的有uveitic绿内障的56个病人的67只眼睛。治疗的成功被定义为完成压力(IOP)从基线IOP在6和21公里Hg之间铺平与或没有另外的反绿内障药或最少20%减小的intraocular的病人。主要结果大小包括了IOP，在1点的绿内障药的数字，3，6，12，24，36，48并且在外科以后的60mo，外科的复杂并发症，最后的改正最好的视觉尖酸(BCVA)，吗视觉地(VF)和网膜的神经纤维层(RNFL).RESULTSThe平均数后续是53.3灡?潬桲硥獩？？

简介：AIM:Todescribetheclinicalfeatures,systemicassociations,treatmentandvisualoutcomesinSaudipatientswithscleritis.·METHODS:AretrospectivechartreviewwasperformedforpatientswithscleritispresentingtotwotertiarycareeyehospitalsinRiyadh,SaudiArabia,from2001to2011.Datawerecollectedontheclinicalfeaturesofscleritis,subtypesofscleritis,associatedsystemicdisease,historyofpreviousocularsurgeryandmedicaltherapy,includingtheuseofimmunosuppressants.Treatmentoutcomeswereevaluatedbasedonbest-correctedvisualacuity(BCVA)andresponsetotreatment.·RESULTS:Ofthe52patientsincludedinthestudy,non-necrotizinganteriorscleritiswasthemostcommontypeofscleritisin22patients(42.3%),followedbyposteriorscleritisin14patients(26.9%).Themajorityofcases,31patients(59.6%),wereidiopathicinnature.Systemicassociationswerepresentin12patients(23.1%).Infectiousscleritiswasconfirmedin6patients(11.5%):3withbacterialscleritisafterpterygiumexcision,2patientswithscleritisrelatedtotuberculosisand1patientwithscleritisresultingfromherpessimplexinfection.Forthevarioussubtypesofscleritis,BCVAvaluesaftertreatmentandtimetoremissionsignificantlydiffered(P<0.05,allcases).Systemicimmunosuppressivetherapiesinadditiontosteroidswereadministeredto46.2%ofallpatients.TheT-signwaspresentonB-scanultrasonographyin9(64.3%)ofthe14posteriorscleritispatients.·CONCLUSION:Non-necrotizinganteriorscleritiswasthemostcommonsubtypeofscleritis.Finalvisualoutcomeandtimetoremissiondifferedamongthevariousscleritissubtypes.

简介：AIMTo调查经历了intravitrealranibizumabmonotherapy对待neovascular的病人的长期的视觉、解剖的结果年龄相关的有斑点的退化(AMD)并且为经历了ranibizumabmonotherapy因为neovascularAMD在这回顾的study.RESULTSThe一般水准病人年龄被包括的74个病人的74只眼睛的至少2y.METHODSA总数跟随起来是72.1

简介：AIM:Tocomparetheclinicaloutcomesofcombined25-gaugeparsplanavitrectomy（PPV）andphacoemulsification/posteriorchamberintraocularlens（PC-IOL）implantationwithvitrectomyalonesurgeryinpatientswithvariousvitreoretinaldiseases.METHODS:Atotalof306eyes（145withPPValoneand161withphaco-vitrectomy）wereenrolledinthisretrospectiveanalysis.Thesurgicalapproachwas25-gaugePPVcombinedwithphacoemulsificationandPC-IOLimplantationatthesametimeineyesinphaco-vitrectomygroupandonlyPPVineyesinvitrectomyalonesurgerygroup.Themainoutcomemeasureswerepostoperativeclinicaloutcomesincludedanteriorchamberinflammation,changesinintraocularpressure（IOP）andbestcorrectedvisualacuity（BCVA）.RESULTS:Themostcommonpostoperativecomplicationwasanteriorchamberreactionwhichhashigherincidenceinphaco-vitrectomygroup（P<0.001）.Themeanpostoperative1stdayIOPofvitrectomyalonegroupwassignificantlylowerthanthatofphaco-vitrectomygroup（16.3±5.8mmHgvs17.8±8.1mmHg,respectively,P=0.02）.Hypotony(IOP（8mmHg）wasnotdifferentbetweengroupsinthepostoperative1stday（P>0.05）.Themeanpreoperativevisualacuitywasnotdifferentbetweengroups（1.6±0.9logMARvs1.8±0.9logMAR,respectively,P>0.05）.However,themeanvisualacuitywasdecreasedinvitrectomyalonegroupatthefinalvisitcomparedtophaco-vitrectomygroup（1.2±0.8logMAR,0.9±0.7logMAR,respectivelyP<0.05）.CONCLUSION:Twenty-fivegaugePPVcombinedwithphacoemulsificationsurgeryisasafeandefficientprocedure,whichcanbepreferredinphacicpatientswithavarietyofvitreoretinaldiseasescomparedtovitrectomyalone.Despiteimprovedoutcomes,thisapproachisnotfreeoflimitationsasanteriorchambercomplicationsespeciallywithcombinedsurgery.

简介：AIM:Todeterminereallifeclinicaloutcomesinpoorlyresponsiveandtreatment-naveneovascularage-relatedmaculardegeneration(nvAMD)patientsusingbimonthlyfixeddosingafliberceptregimen.METHODS:Thiswasaretrospectivestudyof165eyeswithnvAMDstartedonafliberceptatSouthamptonEyeUnitbetweenJune2013andJune2014.Patientswereeitherswitchedfromprorenata(PRN)ranibizumab/bevacizumabduetopoorresponse(107eyes),ortreatment-nave(58eyes).Patientsinitiallyreceived3-monthlyintravitrealafliberceptinjectionsfollowedby2-monthlyfixeddoses.Clinicvisitswerescheduledatmonth0,4,10and12.Meanchangeinbest-correctedvisualacuity(BCVA)andcentralretinalthickness(CRT)frombaselinewereassessedusingtheWilcoxonsignedranktest.TheproportionofpatientsmaintainingBCVA(<15lettersloss)at12mowasalsoevaluated.RESULTS:MeanBCVAchangeatmonth12was+3.29and+4.67lettersintheswitchedandnaveafliberceptgroupsrespectively(P<0.01).BCVAwasmaintainedin95.3%ofswitchedand96.6%ofnavepatients.CRTatmonth12showedadecreaseof-6.16μmintheswitchedgroupand-35.36μminthenavegroup(P<0.01).Patientspreviouslytreatedwithranibizumab/bevacizumabhadonaveragereceived7.4ranibizumab/bevacizumabinjectionsover12.6mo,attending10clinicvisits.Thefixeddosingafliberceptregimenrequiredanaverageof7.1injections(navegroup),7.5injections(switchedgroup)and4clinicvisitsperyear.CONCLUSION:Fixedbimonthlyafliberceptiseffectiveinbothtreatment-naveandpoorlyresponsivenvAMDpatients.Adoptingafixeddosingregimencanreducepatientburdenwithoutcompromisingonoutcomes.

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简介：AIMTo与有斑点的浮肿在病人在中央子字段foveal厚度(CSFT)上为intravitrealbevacizumab注射的短期的效果调查预兆的因素(我)对.METHODSThis是的中央网膜的静脉吸藏(CRVO)第二等在由于CRVO为我与intravitrealbevacizumab注射对待的60只眼睛的回顾的研究。后续是三个月。光谱域的光连贯断层摄影术(SD10月)测量的早治疗糖尿病的Retinopathy学习(ETDRS)分数和CSFT被用来在改正最好的视觉尖酸(BCVA)观察变化。基线BCVA，CSFT，年龄，CRVO持续时间和似胞的有斑点的浮肿(CME)或subretinal液体(SRF)的存在作为bevacizumabinjections.RESULTSBCVA在3mo在基线从0.9logMAR改进了到0.6logMAR的intravitreal的效果的潜在的预兆的因素被分析，它从721µ在CSFT与重要减小被联系；m到392µ；在注射以后的m3mo。大约50%CME盒子和超过90%SRF盒子在3mo与一个完全的决定对治疗作出回应。年龄(P=0.036)和低基线CSFT(P=0.037)与好3月的预后被联系。病人>；60岁在3mo完成了更好的CME分辨率(P=0.031)和更低的CSFT(305µ；m对474µ；m，P=0.003).CONCLUSIONIntravitrealbevacizumab显著地在3mo以后与CRVO在病人改进了视觉尖酸和CSFT。老年和更低的基线CSFT是短期的CSFT结果的好预言者。对bevacizumab的网膜的厚度反应可能取决于CME而非SRF的决定。

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