简介：摘要目的探讨如何在“三查七对”的基础上，使用术前核查表，执行Time-Out核查制度，严格手术核对程序，杜绝错误手术发生。方法从手术室门口接手术患者的核对，到手术间巡回护士的核对，最后由手术医生、麻醉医生、手术室护士在皮肤消毒前共同核对，并分别签名确认，层层把关，杜绝错误手术。结果我院自使用核查表和执行Time-Out核查程序到手术流程中，增加了患者的安全系数，有效控制了差错事故及医疗纠纷的发生1。结论切实做好术前患者核对工作是防止手术患者及手术部位错误的最有效方法。在麻醉前、手术前、术后实施安全核查制度，有效控制了差错事故及医疗纠纷的发生率，应该在临床推广应用。

简介：Objective:　Toexploretheregulationofearlybraintissuemetabolicchangingafterbraininjuriesandtheclinicalsignificance.　　Methods:　Therewere17patientswithbraininjuries.EarlydirectmonitoringofPtiO2,PtiCO2,pHandbraintemperature,dynamicobservationoftherelationbetweenvariousparametersandclinicsafterbraininjurieswereperformed.　　Results:　EarlychangesofPtiO2,PtiCO2andpHwerecloselycorrelatedwithoutcome.ThedeathrateobviouslyincreasedwhenPtiO2wascontinuouslylowerthan9mm?Hgwithin24hoursafterinjuries.Secondarybraininjuryprolongedandaggravatedbraintissuemetabolicdisturbance.Whenintracerebralpressurewasover30mm?HgPtiO2begantodecrease.Thebraintemperatureinbraindeathpatientswasevidentlylowerthanaxillarytemperature.　　Conclusions:　ThedirectmonitoringofPtiO2,PtiCO2,pHandbraintemperatureissafeandaccurateandcanfindearlyanoxiadamagetobraintissueandprovidereliablebasisforclinicaltherapy.Ithasaninstructivesignificanceinselectingandstudyinganewtreatmentmethodinbraininjuries.Anditcanbetakenasacriterioninclinicaljudgingbraindeaths.

简介：摘要：目的：获得单个健康的活产婴儿是辅助生殖治疗的最终目的，本研究利用Time-lapse技术，观察分析单精子卵胞浆内注射（intracytoplasmic sperm injection，ICSI）治疗患者早期胚胎的相关动态学参数，研究其对妊娠结局的影响。方法：通过常规条件培养和Time-lapse培养后临床结局的比较，探讨Time-lapse培养的安全性和可行性；对行Time-lapse培养的胚胎，分析各早期动态学参数之间的联系，及其对妊娠结局的影响。结果：Time-lapse培养组患者临床结局略优于常规组患者，早期动态学参数对妊娠结局无显著性影响，但妊娠组的早期动态学参数出现的时间略早于非妊娠组。

简介：Objective:Tostudythechangesofpartialpressureofbraintissueoxygen(PbtO2)andbraintemperatureinacutephaseofsevereheadinjuryduringmildhypothermiatherapyandtheclinicalsignificance.Methods:Onehundredandsixteenpatientswithsevereheadinjurywereselectedanddividedintoamildhypothermiagroup(n=58),andacontrolgroup(n=58)accordingtooddandevennumbersofhospitalization.WhilemildhypothermiatherapywasperformedPbtO2andbraintemperatureweremonitoredfor1-7days(mean=86hours),simultaneously,theintracranialpressure,rectumtemperature,cerebralperfusionpressure,PaO2andPaCO2werealsomonitored.Thepatientswerefollowedupfor6monthsandtheprognosiswasevaluatedwithGOS(Glasgowoutcomescale).Results:ThemeanvalueofPbtO2within24hourmonitoringinthe116patientswas13.7mmHg±4.94mmHg,lowerthanthenormalvalue(16mmHg±40mmHg)ThetimeofPbtO2recoveringtothenormalvalueinthemildhypothermiagroupwasshortenedby10±4.15hourscomparedwiththecontrolgroup(P<0.05).Thesurvivalrateofthemildhypothermiagroupwas60.43%,higherthanthatofthecontrolgroup(46.55%).Aftertherecoveryofthebraintemperature,PbtO2increasedwiththeriseofthebraintemperature.Conclusions:Mildhypothermiacanimprovethesurvivalrateofsevereheadinjury.ThetechniqueofmonitoringPbtO2andthebraintemperatureissafeandreliable,andhasimportantclinicalsignificanceinjudgingdiseaseconditionandinstructingclinicaltherapy.

简介：【摘要】目的 探索“TIME-CDST 原则”指导下肛周坏死性筋膜炎术后伤口床准备的临床疗效。方法 回顾性分析 2018 年3月至 2020 年5 月乐山市中医院肛肠科收治的 5 例肛周坏死性筋膜炎患者，在“TIME-CDST 原则”指导下肛周坏死性筋膜炎术后伤口床准备的临床资料。5 例患者全部治愈（图7）。住院 10-15 天，换药时间20-30 天，三月后随访确认无术后致残