简介:Inthispaperwedevelopanelasto-dynamicmodelofthehumanarmforuseinneuro-muscularcontrolanddynamicinteractionstudies.Themotivationforthisworkistopresentacasefordevelopingandusingnon-quasistaticmodelsofhumanmusculo-skeletalbiomechanics.Themodelisbasedonhybridparametermultiplebodysystem(HPMBS)variationalprojectionprinciples.Inthispaper,wepresentanoverviewoftheHPMBSvariationalprincipleappliedtothefullelasto-dynamicmodelofthearm.Thegeneralityofthemodelallowsonetoincorporatemuscleeffectsaseitherloadstransmittedthroughthetendonatpointsoforiginandinsertionorasaneffectivetorqueatajoint.Thoughthetechniqueissuitablefordetailedboneandjointmodeling,wepresentinthisinitialeffortonlysimplegeometrywiththebonesdiscretizedasRayleighbeamswithelongation,whileallowingforlargedeflections.Simulationsdemonstratetheviabilityofthemcthodforuseinthecompanionpaperandinfuturestudies.
简介:ThispaperisfocusedonthemodelidentificationofaMicroAirVehicle(MAV)instraightsteadyflightcondition.Theidentificationisbasedoninput-outputdatacollectedfromflighttestsusingbothfrequencyandtimedomaintechniques.Thevehicleisanin-house40cmwingspanairplane.Becauseofthecomplexcoupled,multivariableandnonlineardynamicsoftheaircraft,linearSISOstructuresforboththelateralandlongitudinalmodelsaroundareferencestatewerederived.TheaimoftheidentificationistoprovidemodelsthatcanbeusedinfuturedevelopmentofcontroltechniquesfortheMAV.
简介:Indryattachmentsystemsofspidersandgeckos,vanderWaalsforcesmediateattractionbetweensubstrateandanimaltarsus.Inparticular,thescopulaofEvarchaarcuataspidersallowsforreversibleattachmentandeasydetachmenttoabroadrangeofsurfaces.Hence,reproducingthescopula’sroughnesscompatibilitywhilemaintaininganti-bunchingfeaturesanddirtparticlerepellencebehaviorisacentraltaskforabiomimetictransfertoanengineeredmodel.InthepresentworkwemodelthescopulaofE.arcuatafromamechano-elasticpointofviewanalyzingtheinfluenceofitshierarchicalstructureontheattachmentbehavior.Byconsideringbiologicaldataofthegeckoandspider,andthesimulationresults,theadhesivecapabilitiesofthetwoanimalsarecomparedandimportantconfirmationsandnewdirectivesinordertoreproducetheoverallstructurearefound.Moreover,apossiblesuggestionofhowthespiderdetachesinaneasyandfastmannerisproposedandsupportedbytheresults.
简介:Extenicsisanewlydevelopedinterdisciplinarysubjectcombiningmathematics,philosophyandengineering.Itprovidesusefulformalizedqualitativetoolsandquantitativetoolsforsolvingcontradictoryproblems.Inthispaper,extensiontheoryisintroducedbrieflyandtheprimaryapplicationsofthistheoryandmethodsinbionicengineeringresearcharediscussed.Theextensionmodelofbiologicalcouplingfunctionalsystemisestablished.Inordertoidentifytheprimaryandsecondarysequencingofcouplingelements,theExtensionAnalyticHierarchyProcess(EAHP)wasadoptedtoanalyzethecontributionofeachcouplingelementtothecouplingfunctionalsystem.Thus,theinfluenceweightfactorofeachcouplingelementcanbedetermined,soastoprovideanewapproachforsolvingprimaryandsecondarysequencingproblemofcouplingelementsinaquantitativeway,andfacilitatethesubsequentbioniccouplingstudy.
简介:Reliablecomputationalfootmodelsofferanalternativemeanstoenhanceknowledgeonthebiomechanicsofhumanfoot.Modelvalidationisoneofthemostcriticalaspectsoftheentirefootmodelingandanalysisprocess.Thispaperpresentsaninvivoexperimentcombiningmotioncapturesystemandplantarpressuremeasureplatformtovalidateathree-dimensionalfiniteelementmodelofhumanfoot.TheMagneticResonanceImaging(MRI)slicesforthefootmodelingandtheexperimentaldataforvalidationwerebothcollectedfromthesamevolunteersubject.Thevalidatedcomponentsincludedthecomparisonofstaticmodelpredictionsofplantarforce,plantarpressureandfootsurfacedeformationduringsixloadingconditions,toequivalentmeasureddata.Duringthewholeexperiment,footsurfacedeformation,plantarforceandplantarpressurewererecordedsimultaneouslyduringsixdifferentloadedstandingconditions.ThepredictionsofthecurrentFEmodelwereingoodagreementwiththeseexperimentalresults.
简介:Basedonauditoryperipheralsimulationmodel,anewSoundQualityObjectiveEvaluation(SQOE)methodispresented,whichcanbeusedtomodelandanalyzetheimpactsofhead,shoulderandotherpartsofhumanbodyonsoundwavetrans-mission.Thismethodemploystheartificialheadtechnique,inwhichtheheadrelatedtransferfunctionwastakenintoaccounttotheouterearsimulationphase.First,abionicartificialheadwasdesignedastheouterearmodelwithconsideringtheoutersoundfieldinviewoftheoryandphysicalexplanations.Thentheauditoryperipheralsimulationmodelwasbuilt,whichmimicsthephysiologicalfunctionsofthehumanhearing,simulatingtheacousticsignaltransferprocessandconversionmechanismsfromthefreefieldtotheperipheralauditorysystem.Finally,performancecomparisonwasmadebetweentheproposedSQOEmethodandArtemiSsoftware,andtheverificationsofsubjectiveandobjectiverelatedanalysisweremade.Resultsshowthattheproposedmethodwaseconomical,simple,andwithgoodevaluationquality.
简介:Insteadofvision,manynocturnalanimalsusealternativesensesfornavigationandobjectdetectionintheirdarkenvi-ronment.Forthispurpose,weaklyelectricmormyridfishemployactiveelectrolocation,duringwhichtheydischargeaspe-cializedelectricorganintheirtailwhichdischargeselectricalpulses.Eachdischargebuildsupanelectricalfieldaroundthefish,whichissensedbycutaneouselectroreceptororgansthataredistributedovermostofthebodysurfaceofthefish.Nearbyobjectsdistortthiselectricalfieldandcausealocalalterationincurrentflowinthoseelectroreceptorsthatareclosesttotheobject.Byconstantlymonitoringresponsesofitselectroreceptororgans,afishcandetect,localize,andidentifyenvironmentalobjects.Inspiredbytheremarkablecapabilitiesofweaklyelectricfishindetectingandrecognizingobjects,wedesignedtechnicalsensorsystemsthatcansolvesimilarproblemsofremoteobjectsensing.Weappliedtheprinciplesofactiveelectrolocationtotechnicalsystemsbybuildingdevicesthatproduceelectricalcurrentpulsesinaconductingmedium(waterorionizedgases)andsimultaneouslysenselocalcurrentdensity.Dependingonthespecifictaskasensorwasdesignedfordevicescould(i)detectanobject,(ii)localizeitinspace,(iii)determineitsdistance,and(iv)measurepropertiessuchasmaterialproperties,thickness,ormaterialfaults.Oursystemsprovedtoberelativelyinsensitivetoenvironmentaldisturbancessuchasheat,pressure,orturbidity.Theyhaveawiderangeofapplicationsincludingmaterialidentification,qualitycontrol,non-contactdistancemeasurements,medicalapplicationsandmanymore.Despitetheirastonishingcapacities,oursensorsstilllagfarbehindwhatelectricfishareabletoachieveduringactiveelectrolocation.Theunderstandingoftheneuralprinciplesgoverningelectricfishsensoryphysi-ologyandthecorrespondingoptimizationofoursensorstosolvecertaintechnicaltasksthereforeremainongoinggoalsofourresearc
简介:Inthispaperwedevelopanelasto-dynamicmodelofthehumanarmthatincludeseffectsofneuro-muscularcontroluponelasticdeformationinthelimb.Theelasto-dynamicmodelofthearmisbasedonhybridparametermultiplebodysystemvariationalprojectionprinciplespresentedinthecompanionpaper.Thoughthetechniqueissuitablefordetailedboneandjointmodeling,wepresentsimulationsforsimplifiedgeometryofthebones,discretizedasRayleighbeamswithelongation,whileallowingforlargedeflections.MotionoftheupperextremityissimulatedbyincorporatingmuscleforcesderivedfromaHill-typemodelofmusculotendondynamics.Theeffectsofmuscleforcearemodeledintwoways.Inoneapproach,aneffectivejointtorqueiscalculatedbymultiplyingthemuscleforcebyajointmomentann.Asecondapproachmodelsthemuscleasactingalongastraightlinebetweentheoriginandinsertionsitesofthetendon.Simplearmmotionissimulatedbyutilizingneuralfeedbackandfeedforwardcontrol.Simulationsillustratethecombinedeffectsofneuralcontrolstrategies,modelsofmuscleforceinclusion,andelasticassumptionsonjointtrajectoriesandstressandstraindevelopmentintheboneandtendon.
简介:从药用植物中华芦荟组织中分离出一株抗菌内生细菌A11#,该菌产生广谱抗菌活性物质,对金黄色葡萄球菌、枯草芽孢杆菌等革兰氏阳性细菌和植物病原真菌均有较强的抑制作用;通过形态学观察及生理生化特征测定,初步鉴定归属于芽孢杆菌属(Bacillus).该菌在初始pH值为5.O~10.0的PDA培养基上生长旺盛,生长最适pH为5~7,培养液初始pH为6~10时发酵产生大量粘性物质;生长温度范围在10~45℃,最适温度28~37℃;在初始pH5.0和30.5℃条件下发酵,其发酵液抑菌作用最强;该菌所产抗菌物质能耐121℃处理30min而不影响其活性.在阿须贝无氮培养基上生长良好,在不加葡萄糖、蔗糖或淀粉的LB和牛肉膏蛋白胨培养基上不生长;同时还产生对高岭土有絮凝活性的物质.
简介:ThespinesofpencilandlanceurchinsHeterocentrotusmammillatusandPhyllacanthusimperialiswerestudiedasamodeloflight-weightmaterialwithhighimpactresistance.Thecomplexandvariableskeletonconstruction("stereom")ofbodyandspinesofseaurchinsconsistsofhighlyporousMg-bearingcalciumcarbonate.Thisbasicallybrittlematerialwithpronouncedsingle-crystalcleavagedoesnotfracturebyspontaneouscatastrophicdevicefailurebutbygracefulfailureovertherangeoftensofmillimeterofbulkcompressioninstead.Thiswasobservedinbulkcompressiontestsandbluntindentationexperimentsonregular,infiltratedandlatexcoatedseaurchinspinesegments.MicrostructuralcharacterizationwascarriedoutusingX-raycomputertomography,opticalandscanningelectronmicroscopy.Thebehaviorisinterpretedtoresultfromthehierarchicstructureofseaurchinspinesfromthernacroscaledowntothenanoscale.Guidelinesderivedfromthisstudyseeceramicswithlayeredporosityasapossiblebiomimeticconstructionforappropriateapplications.
简介:目的:调查姜黄根茎内生真菌对姜黄素的微生物转化,以期获得一些姜黄素的结构类似物或衍生物。方法:利用表面消毒法分离内生真菌;采用薄层层析和高效液相色谱(HPLC)技术筛选生物转化姜黄素的内生真菌;利用硅胶柱层析和制备型HPLC分离纯化生物转化产物;应用波谱技术解析转化产物的化学结构;通过形态学特征和内转录间隔区(ITS)序列分析对内生真菌进行初步鉴定。结果:从姜黄根茎中分离出18株内生真菌,经筛选发现其中1株丝状真菌能转化姜黄素,其产物分别为去甲基姜黄素和二去甲基姜黄素。初步鉴定该内生真菌属于Durporthesp.。结论:内生真菌Diaporthesp.能对姜黄素进行去甲基化修饰,推测它可能具有O-去甲基化酶系。
简介:Seaurchinspineswerechosenasamodelsystemforbiomimeticceramicsobtainedusingstarch-blendedslipcasting.Porousaluminaceramicswithcap-shapedlayerswithdifferentalternatingporositieswerefoundtohavesuperiorfracturebehaviorunderbulkcompressioncomparedtoceramicswithuniformporosity.Theyfailinacascadingmanner,absorbinghighamountsofenergyduringextendedcompressionpaths.TheporosityvariationinanotherwisesinglephasematerialmimicksthearchitecturalmicrostructuredesignofseaurchinspinesofHeterocentrotusmammillatus,whicharepromisingmodelmaterialsforimpactprotection.
简介:目的:探讨足月妊娠应用普贝生引产的临床疗效以及不良反应.方法:选取我院2014年2月到11月中80例足月妊娠有引产特征的孕妇,分为试验组和对照组,每组各40例,试验组给予普贝生引产,对照组给予缩宫素,观察两组的临床效果以及发生的不良反应.结果:试验组的有效率为95.0%明显的高于对照组的有效率70.0%,两组有效率之间的差异具有明显的统计学意义(P〈0.05),试验组的显效率为77.5%明显的高于对照组的37.5%,两组有效率之间的差异具有显著的统计学意义(P〈0.05);结论:足月妊娠应用普贝生引产的临床效果好,可以降低剖宫产率,而且安全性好值得临床上推广.