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  • 简介:  【摘 要】 目的:比较三种不同麻醉剂联合无抽搐电休克治疗用于难治性抑郁症患者的疗效。方法:选择本院 10例难治性抑郁症患者作为研究对象,随机分为研究组和对照组,研究组采用三种不同的麻醉剂联合无抽搐电休克治疗,对照组常规药物治疗,对比疗效差异。结果:治疗后,研究组认知功能改善情况、抑郁评分情况、社会功能改善情况均显著优于对照组,差异显著( P<0.05)。结论:三种麻醉剂联合无抽搐电休克治疗难治性抑郁症对患者的认知情况改善,抑郁评分情况改善更加有效。    【关键词】 麻醉剂 ;无抽搐电休克 ;难治性抑郁 ;认知功能    [Abstract] Objective: To compare the efficacy of three different anesthetics combined with non convulsive electroconvulsive therapy in patients with refractory depression. Methods: 10 patients with refractory depression in our hospital were randomly divided into study group and control group. The study group was treated with three different anesthetics combined with non convulsive electroconvulsive therapy, while the control group was treated with conventional drugs, and the therapeutic effect was compared. Results: after treatment, the improvement of cognitive function, depression score and social function in the study group were significantly better than those in the control group (P < 0.05). Conclusion: three kinds of anesthetics combined with electroconvulsive therapy can improve the cognitive status of patients with refractory depression, and improve the depression score more effectively.

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  • 简介:   【摘要】 目的:探討双相情感障碍躁狂发作患者采用奥氮平联合碳酸锂治疗的临床效果。方法:选取 2018年 1月 -2020年 3月笔者所在医院收治的 82例双相情感障碍躁狂发作患者,采用红蓝双色球法分为两组,各 41例。对照组采用碳酸锂治疗,观察组采用奥氮平联合碳酸锂治疗,比较两组治疗前及治疗 8周后症状变化情况、临床效果及不良反应发生率。结果:治疗前两组临床总体印象疾病严重度量表 -双相障碍版( CGI-s-BP)、 Bech-Rafaelsen躁狂量表( BRMS)评分对比,差异均无统计学意义( P>0.05) ;治疗后观察组 CGI-s-BP评分为( 2.53±0.37)分, BRMS评分为( 20.42±1.51)分,均低于对照组的( 4.25±0.81)和( 24.37±1.63)分,差异均有统计学意义( P<0.05) ;观察组总有效率( 97.56%)高于对照组( 80.49%),差异有统计学意义( P<0.05) ;观察组与对照组不良反应发生率分别为 19.51%、 14.63%,差异无统计学意义( P>0.05)。结论:给予双相情感障碍躁狂发作患者奥氮平联合碳酸锂治疗能够明显改善临床症状,提高治疗效果,安全性良好。     【关键词】 双相情感障碍 躁狂发作 奥氮平 碳酸锂 安全性 

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