简介: 【摘 要】目的:分析不同剂量辛伐他汀治疗高血压合并高脂血症的效果及安全性。方法:在 2018年 1月到 2019年 3月选取我院接诊的老年高血压、高脂血症患者 200例作为案例进行研究分析。以随机数字法方式分组。两组患者均应用辛伐他汀进行治疗。常规组在睡前应用低剂量辛伐他汀,实验组在睡前应用高剂量辛伐他汀。总结并对比两组患者的血压、血脂指标以及不良反应发生率。结果:治疗前两组患者的血压指标差异不突出,对比结果无意义( P>0.05)。实验组患者的 24小时平均收缩压显著优于常规组,组间对比结果差异显著,满足统计学意义标准( P<0.05) ;治疗前两组患者的血脂指标差异不突出,对比结果无意義( P>0.05)。实验组患者的各项血脂指标均显著优于常规组,组间对比结果差异显著,满足统计学意义标准( P<0.05) ;两组患者在治疗期间均无严重不良反应,数据无差异( P>0.05)。结论:不同剂量辛伐他汀治疗高血压合并高脂血症的效果差异较大,高剂量( 40mg/次)的用量相对于低剂量( 20mg/次)的用药方式具备更加突出的临床疗效,整体治疗效果突出,值得推广普及。 【关键词】辛伐他汀 ;高血压 ;高脂血症 ;临床疗效 ;安全性 Objective: to analyze the efficacy and safety of different doses of simvastatin in the treatment of hypertension complicated with hyperlipidemia. Methods: from January 2018 to March 2019, 200 elderly patients with hypertension and hyperlipidemia in our hospital were selected as cases for study and analysis. They were grouped by random number method. Both groups were treated with simvastatin. The conventional group was given low-dose simvastatin before going to bed, while the experimental group was given high-dose simvastatin before going to bed. The blood pressure, blood lipid index and incidence of adverse reactions were summarized and compared between the two groups. Results: there was no significant difference in blood pressure index between the two groups before treatment (P > 0.05). The 24-hour mean systolic blood pressure of the experimental group was significantly better than that of the conventional group, and the difference between the two groups was significant (P < 0.05); before treatment, the difference of blood lipid index between the two groups was not prominent, and the comparison result was not significant (P > 0.05). The blood lipid indexes of the experimental group were significantly better than those of the conventional group, and the difference between the two groups was significant (P < 0.05); there was no serious adverse reaction in the two groups during the treatment, and the data had no difference (P > 0.05). Conclusion: the effect of different doses of simvastatin in the treatment of hypertension complicated with hyperlipidemia is quite different. The dosage of high-dose (40mg / time) has more prominent clinical effect than the low-dose (20mg / time), and the overall treatment effect is outstanding, which is worthy of popularization.
简介:【摘要】:目的:针对延续性护理在老年冠心病合并慢性高血压患者中的应用效果进行分析。 方法:选取本院2019年6月至2020年2月收治的66例冠心病合并慢性高血压患者为研究对象,采用随机数字分组法,将患者分为观察组和对照组,每组均为33例。对照组进行常规护理,观察组采取常规护理+延续性护理。分析2组护理满意度和生活质量。 结果:观察组总满意率高于对照组(p值<0.05);观察组和对照组出院前生活质量评分(p值>0.05),出院后1个月和3个月观察组优于对照组(p值<0.05)。 结论:延续性护理在老年冠心病合并慢性高血压患者中,能有效提高患者生活质量和护理满意度。
简介:【摘要】:目的:分析针对性护理用于急性上消化道出血患者中心理状况的临床效果。方法:选取2018年12月至2019年12月间到本院收治的上消化道出血患者82例随机分成两组,对照组41例采取常规护理,对观察组41例则采取针对性的护理;比较两组患者各项评分以及两组患者对护理服务的满意度。结果:经过护理后,对照组患者的SAS、SDS、VAS等评分值高于观察组(P<0.05);观察组对护理工作满意度高于对照组患者(