Introduction:Anumberofmilestonesinthetreatmentofprematureejaculation(PE)haveoccurredoverthepastfivedecades,includingthedevelopmentofvariousbehavioralandcognitivetechniquesaswellaspharmacotherapiesthatmodifyneurophysiologicalprocessesinvolvedinejaculation.Nevertheless,thenotionthatsexualresponsessuchasPEareinfluencedbyphysiological,