甲基强的松龙联合常规西药治疗小儿急性肾炎的疗效分析

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摘要    [摘要 ] 目的 探析小儿急性肾炎应用甲基强的松龙结合常规西药治疗的临床效果。方法 方便选取该院 2018年 1月— 2020年 2月期间收治的 60例急性肾炎患儿予以分析,根据病床单双号法分为两组,即单号组与双号组,各组 30例。单号组予以常规西药治疗,双号组予以甲基强的松龙结合常规西药治疗,对两组临床疗效、临床症状改善时间进行统计分析。 结果 双号组总有效率为 96.7%,高于单号组的 80.0%,对比差异有统计学意义( P<0.05)。双号组水肿消失时间为( 3.0±1.5) d,血尿消失时间为( 2.5±1.4) d,血压恢复正常时间为( 4.3±1.3) d,蛋白尿消失时间为( 9.0±1.7) d,均短于单号组的( 4.0±1.7)、( 4.2±1.3)、( 5.7±1.5)、( 12.4±1.7) d,对比差异有统计学意义( P<0.05)。结论 小儿急性肾炎应用甲基强的松龙结合常规西药治疗的临床效果更好,值得临床应用与推广。     [关键词 ] 小儿急性肾炎;甲基强的松龙;临床效果  [Abstract] Objective To explore the clinical effect of methylprednisolone combined with conventional western medicine in children with acute nephritis. Methods 60 children with acute nephritis admitted to the hospital from January 2018 to February 2020 were conveniently selected for analysis. According to the single and double number method of hospital bed, they were divided into two groups, namely single number group and double number group, 30 cases in each group. The single group was treated with conventional western medicine, and the double group was treated with methylprednisolone combined with conventional western medicine. Results the total effective rate of double group was 96.7%, which was higher than that of single group (80.0%) (P < 0.05). The disappearance time of edema was (3.0 ± 1.5) d, that of hematuria was (2.5 ± 1.4) d, that of blood pressure was (4.3 ± 1.3) d, that of albuminuria was (9.0 ± 1.7) d, which was shorter than that of single group (4.0 ± 1.7), (4.2 ± 1.3), (5.7 ± 1.5), (12.4 ± 1.7) d. The difference was statistically significant (P < 0.05). Conclusion the clinical effect of methylprednisolone combined with conventional western medicine is better in children with acute nephritis, and it is worthy of clinical application and promotion.
出处 《中华医学信息导报》 2020年4期
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出版日期 2020年06月15日(中国期刊网平台首次上网日期,不代表论文的发表时间)