人类乳头状瘤病毒、阴道毛滴虫与宫颈细胞学的相关性研究

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摘要 摘要目的探讨人类乳头病毒或者阴道毛滴虫与宫颈细胞学改变的相关性.方法收集本院8460例患者的宫颈脱落细胞及阴道分泌物标本.生理盐水悬滴法鉴定阴道毛滴虫,HCⅡ法鉴定人类乳头病毒,液基薄层细胞术鉴定宫颈细胞学改变.结果高危型HPV感染率(34.65%)远高于于阴道毛滴虫的感染率(2.98%)(P<0.001).HPV(OR50.716)、TV(OR3.258)单个感染或者HPV、TV(OR101.058)共同感染均与宫颈细胞学阳性改变有关.HPV感染导致的细胞学检测阳性主要集中在ASCUS36.43%(513/1408)、LSIL44.89%(632/1408)、HSIL13.85%(195/1408).而TV感染导致的细胞学检测阳性主要集中在ASCUS65.52%(38/58).结论HPV和TV感染均可以导致宫颈细胞学检查阳性,HPV比TV更容易导致宫颈细胞学检查阳性,且细胞学改变比TV较重.关键字阴道毛滴虫;人类乳头状瘤病毒;宫颈细胞学;薄层液基细胞术CorrelationstudyofHumanpapillomavirus、TrichomonasvaginalisandcervicalcytologyYaoFeng;ZhangYu-quan;LiHong-yu;ZhangJian-lin;YangYi-mei;Wangshan-shan;ChenCheng;ZhangJun-rongDeApbasrttrmacetntOobfjgeyctniaveecologyandobstetrics,Affiliatedhospitalofnantonguniversity,Nantong,226001TostudytherelativitybetweenHumanpapillomavirusandcervicalcytology,andtherelativitybetweenTrichomonasvaginaGlisandcervicalcytology.MethodsExfoliatedcellsincervixuteriandVaginalfluidof8460patientswerecollected.Trichomonasvaginaliswasdetectedbythehangingdropmethod.HumanpapillomaviruswasdetectedbyHybridcaptureⅡ.ExfoliatedcellsincervixuteriweredetectedbyThinprepcytolGogytest.ResultsInfectionrateofHumanpapillomavirus(34.65%)washigherthanthatofTrichomonasvaginalis(2.98%)(P<0.001).InfectionofHumanpapillomavirus(OR50.716)orTrichomonasvaginalis(OR3.258)alonecanbethereasonofpositivecervicalcytologydetection.AndInfectionoftwofactorstogether(OR101.058)also.36.43percentofthepositivecervicalcytologydetectionresultscausedbyinfectionofHumanpapillomaviruswasASCUS.44.89percentofthatwasLSIL.And13.85percentofthatwasHSIL.65.52percentofthepositivecervicalcytologydetectionresultscausedbyinfectionofTrichomonasvaginaliswasASCUS.ConclusionBecauseofinfectionofHumanpapillomavirusorTrichomonasvaginalis,theresultsofcerGvicalcytologydetectionwaspositive.ItiseasierforinfectionofHumanpapillomavirustobringaboutcervicalcytologydetectionpositivethanforinfecGtionofTrichomonasvaginalis.TheresultofcervicalcytologydetectionbecomingpositivecausedbyinfectionofHumanpapillomaviruswasmoreseriousthanthKaetybwyoirndfsectionofTrichomonasvaginalis.Humanpapillomavirus;Trichomonasvaginalis;cervicalcytology;Thinprepcytologytest中图分类号R373文献标识码B文章编号1008-6315(2015)10-0341-02
出处 《中国综合临床》 2015年9期
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出版日期 2015年09月19日(中国期刊网平台首次上网日期,不代表论文的发表时间)
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