Measurement and Prediction of Insertion Force for the Mosquito Fascicle Penetrating into Human Skin-中国期刊网

摘要 Mosquitoesareexceptionalintheirabilitytopierceintohumanskinwithanaturalultimatepainlessmicroneedle,namedfascicle.HerethestructureoftheAedesalbopictusmosquitofascicleisobtainedusingaScanningElectronMicroscope(SEM),andthewholeprocessofthefascicleinsertingintohumanskinisobservedusingahigh-speedvideoimagingtechnique.Directmeasurementsoftheinsertionforceformosquitofascicletopenetrateintohumanskinarereported.Resultsshowthatthemosquitousesaverylowforce(average18μN)topenetrateintotheskin.Thisforceisatleastthreeordersofmagnitudesmallerthanthereportedlowestinsertionforceforanartificialmicroneedlewithanultrasharptiptoinsertintothehumanskin.Inordertounderstandthepiercingmechanismofmosquitofascicletipintohumanmultilayerskintissue,anumericalsimulationisconductedtoanalyzetheinsertionprocessusinganonlinearfiniteelementmethod.Agoodagreementoccursbetweenthenumericalresultsandtheexperimentalmeasurements.

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Measurement and Prediction of Insertion Force for the Mosquito Fascicle Penetrating into Human Skin

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Measurement and Prediction of Insertion Force for the Mosquito Fascicle Penetrating into Human Skin

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