简介:摘要目的了解2012年1月1日至2013年12月31日少数民族聚居的大理白族自治州第一人民医院手足口病患儿肠道病毒71型(EV71)的感染状况,为临床诊治提供参考。方法采集首诊手足口病1028例患儿的咽拭子标本,应用实时RT-PCR法检测标本中的EV71。结果1028例手足口病咽拭子样本中EV71的阳性病例数为274;阳性率为26.65%,2013年咽拭子样本EV71阳性检出率30.93%(150/485)高于2012年22.84%(124/543),差异有统计学意义(P<O.05);2012、2013年均以EV71感染为主,病毒流行株差异有统计学意义(P<0.01)。结论2012和2013年我院手足口病患儿EV71检出率分别为22.84%和30.93%是手足口病的主要致病病毒之一,2013年EV71感染的手足口病比例较2012年出现明显上升。EV71是大理白族地区手足口病的主要致病病毒,流行特征和病原学分析有助于手足口病的早期防控和治疗。
简介:目的采用24h动态血压(ABPM)方法探讨直立性高血压(OHT)患儿的血压类型。方法选取2009年10月至2013年9月在中南大学湘雅二医院(我院)儿童晕厥门诊就诊或住院的患儿,以不明原因晕厥及先兆晕厥为主诉,经直立倾斜试验确诊为OHT者为OHT组。与OHT组年龄及性别匹配,选择同期来我院儿童保健门诊检查的健康儿童为对照组。OHT组和对照组均行ABPM监测,观察收缩压昼夜差值、舒张压昼夜差值,24h、日间、夜间平均收缩压和舒张压参数,并探讨血压类型。结果OHT组40例,男23例,女17例,年龄(11.5±1.9)岁。对照组40例,男22例,女18例,年龄(10.6±2.4)岁。1收缩压昼夜差值对照组高于OHT组,(9.8±3.3)vs(8.4±4.7)mmHg,P〈0.05。OHT组24h、日间、夜间的平均收缩压和舒张压稍高于对照组(P〉0.05)。舒张压昼夜差值对照组稍高于OHT组(P〉0.05)。2OHT组以非勺型血压为主(72.5%),对照组以勺型血压为主(55.0%),两组血压类型差异有统计学意义(P=0.012)。结论OHT患儿收缩压昼夜差值较正常儿童明显降低,血压类型以非勺型血压多见,多数患儿血压昼夜节律消失。
简介:Purpose:Theprimaryaimofthisstudywastodevelopanassessmentofthefundamental,combined,andcomplexmovementskillsrequiredtosupportchildhoodphysicalliteracy.Thesecondaryaimwastoestablishthefeasibility,objectivity,andreliabilityevidencefortheassessment.Methods:Anexpertadvisorygrouprecommendedacourseformatfortheassessmentthatwouldrequirechildrentocompleteaseriesofdynamicmovementskills.Criterion-referencedskillperformanceandcompletiontimeweretherecommendedformsofevaluation.Children,8–12yearsofage,self-reportedtheirageandgenderandthencompletedthestudyassessmentswhileattendinglocalschoolsordaycamps.FacevaliditywaspreviouslyestablishedthroughaDelphiexpert(n=19,21%female)reviewprocess.Convergentvaliditywasevaluatedbyageandgenderassociationswithassessmentperformance.Inter-andintra-rater(n=53,34%female)objectivityandtest–retest(n=60,47%female)reliabilitywereassessedthroughrepeatedtestadministration.Results:Mediantotalscorewas21of28points(range5–28).Mediancompletiontimewas17s.Totalscoreswerefeasibleforall995childrenwhoself-reportedageandgender.Totalscoredidnotdifferbetweeninsideandoutsideenvironments(95%confidenceinterval(CI)ofdifference:-0.7to0.6;p=0.91)orwith/withoutfootwear(95%CIofdifference:-2.5to1.9;p=0.77).Olderage(p<0.001,η2=0.15)andmalegender(p<0.001,η2=0.02)wereassociatedwithahighertotalscore.Inter-raterobjectivityevidencewasexcellent(intraclasscorrelationcoefficient(ICC)=0.99)forcompletiontimeandsubstantialforskillscore(ICC=0.69)for104attemptsby53children(34%female).Intra-raterobjectivitywasmoderate(ICC=0.52)forskillscoreandexcellentforcompletiontime(ICC=0.99).Reliabilitywasexcellentforcompletiontimeoverashort(2–4days;ICC=0.84)orlong(8–14days;ICC=0.82)interval.Skillscorereliabilitywasmoderate(ICC=0.46)overashortinterval,a
简介:Theoreticalmodelsofstellarevolutionpredictnegligiblequantitiesof6Li,9Be,and11Binthehydrogenburningphasesofastar’sevolution[1].TheprimordialBig-Bangnucleosynthesis(BBN)modelmightbemoregenerousinitsproductionoftheseelements[2].Theradiative-capturecrosssectionforprotoncaptureon11Bleadingto12CissmallatastrophysicallyinterestingenergiesbecauseofthelargeCoulombbarrier.