简介:AbstractPreeclampsia (PE) is one of the leading causes of maternal and perinatal morbidity and mortality worldwide. This disorder has profound short-term and long-term impacts on both the affected woman’s and her child’s health. Early-onset PE requiring preterm delivery (preterm PE) is of particular importance because it is associated with a higher risk of adverse pregnancy outcomes than term PE. First trimester screening model developed by the Fetal Medicine Foundation (FMF), which uses Bayes-theorem to combine maternal characteristics and medical history together with measurements of mean arterial pressure, uterine artery pulsatility index, and serum placental growth factor, has been proven to be effective and have superior screening performance to that of traditional risk factor-based approach for the prediction of PE. Identification of high risk pregnant women for preterm PE and giving aspirin prophylaxis before 16th week of gestation would reduce the incidence of preterm PE. In Asia, although the prevalence of PE is slightly lower than the global estimation, early screening and prevention of this life-threatening condition is still crucial. The FMF Bayestheorem based screening method has been validated in a large-scale prospective Asia-wide study and revealed that the first trimester triple test achieves the highest detection rate, compared with the traditional risk factor-based approaches, and that the screening performance is comparable to the published data from the FMF in East Asian women. However, in order to achieve optimal screening performance, the key is to establish standardized methods for biomarker measurements and regular biomarker quality assessment, as each biomarker is susceptible to inaccurate measurement, thus affecting performance of screening. Furthermore, it is of great importance to emphasize that the optimal preventive effect of aspirin on preterm PE is clearly associated with good compliance to treatment. In conclusion, global implementation of an effective first trimester "screen and prevent" program for preterm PE would provide the opportunity to reduce the risk of both short-term maternal and perinatal morbidity and mortality, with the possibility of intergenerational prevention of future chronic diseases for both the mother and her offspring.
简介:Dalingheornisliweii情报。etsp。nov,一只新enantiornithine鸟在东北中国从早白垩纪Yixian形成被收集。它是在中生代鸟中的一只高度专业化的异种扬抑抑格脚的第一个记录。有shorthypocleidum的塑造Y的叉突与另外的enantiornithines的不同。未成年者掌部比专业柔韧、长掌部。一条长多骨的尾巴与dromaeosaurids并且这样类似于那些的V形臂章20尾的vertebrae创作了,再加亮在鸟和非鸟的theropods之间的进化关系。保存得很好的小翼羽毛和一只异种扬抑抑格脚为Dalingheornis的树木的习惯提供充分证据。
简介:CambodiaKiriro1stCascadeHydropowerStationisthefirstoverseasBOTprojectoftheStatePowerCorporation(SP).ItisareconstructionprojectwhichiscontractedbyChinaPowerTechnologyImport&ExportCompany(CPTIEC).OnDecember9,2000,theagreementonseller’sexportcreditloanconcernin
简介:烷基配糖物1并且芳基glycosides24stereospecifically高度从商业地可得到的开始的材料在46步上被综合。acetobromo的联合反应--有unprotectivedihydroxyaglycon的D葡萄糖面对钠氢氧化物面对银氧化物,或与芳香的aglycon生产了关键中介。仅仅配置glycosides在这个过程被形成。所有这些glycosides的合成第一次被报导。
简介:TheFirstInternationalCouncilforScience(ICSU)RegionalMeetingforAsiaandthePacificwasheldfromApril25-27,2005inKualaLumpur,Malaysia.ThemeetingwashostedbytheMinistryofScience,TechnologyandInnovationofMalaysiaandtheAcademyofSciencesMalaysia.WelcomingremarksweredeliveredbyTanSriDatukDr.AhmadZaharudinIdrus,President,AcademyofSciencesMalaysiaandProf.ThomasRosswall,ExecutiveDirector,ICSU.HisExcellencyDato'SriDr.JamaludinJarjis,MinisterofScience,TechnologyandInnovation,Malaysiaopenedthemeeting.About40participantsattendedthemeeting,representingnationalscienceacademiesfromtheAsiaPacificandinternationalscientificunionsthatareactiveintheregion.TheInternationalUnionofGeologicalSciences(IUGS)wasrepresentedbythePresident,Prof.ZhangHongren.Dr.JoyPereira,ChairoftheIUGSCommissiononGeoscienceforEnvironmentalManagement(IUGS-GEM)alsoattendedthemeetingasanObserver.
简介:<正>Beingthe"CapitalofSevenDynasties",Kaifengisnotonlyahistoricalancientcity,butonethat"integratesthepreciousfoodalloverthecountry".Yiyin,theso-called"SacredManofCooking"wasbornthere.Youyixinrestaurant,whichislabeledas"TheFirstGenuineHenanCuisine"islocatedatabustlingstreet,Gulou(DrumBuilding)StreetinKaifeng.ItsformernamewasYouyicunRestaurant,whichstartedinthelaterQing
简介:Inthefirsthalfof2015,rareearthmarketdeclinedafteraperiodofpricerising.Rareearthpricesfacedseverdownwardpressurecurrently.Itwasthoughtthefallingtrendcouldlastforsometime.InearlyJanuary,mainstreampriceofdidymiumoxidewas280,000-285,000yuan/ton.Itstartedtoriseslowlyandincreasedby10,000-12,000yuanpertoninearlyFebruary.Thepriceofdidymiumoxidehad
简介:InthelateJulyof1908,OotaniKouzui(1876-1948,the22ndabbotfromoftheJapaneseNishi-honganziMonastery)senthisyoungerbrotherOotaniSonyu(1886-1939)togotoWutaiMountaintosecretlymeetthe13thDalaiLama.ThemonasteryofJapanandthelocalgovernmentofTibethadreachedanagreementontheissueofexchangingstudents.Inaccordancewiththeagreement,AokiBunkyouandTadaToukan,spentthreeandtenyearsrespectivelystudyinginTibet.Andthe13thDalai
简介:Bydeclaring“Fromthisdayforward,anewvisionwillgovernourland.Fromthisdayforward,it’sgoingtobeonlyAmericafirst”1andmaking“AmericaFirst”thecoreprincipleforgovernanceandforeignpolicy,theUSPresidentDonaldTrumphasabandonedthe“globalism”cherishedbysuccessiveAmericanadministrationsinthepost-warera.Althoughthe“TrumpDoctrine”isnotyetclearlydefinedasanoveralldiplomaticstrategy,“AmericaFirst”hasalreadyconstitutedthemostcriticalelementinthisstrategy,representingachangeindirectionfortheUSforeignpolicy.ThedistinctiveprioritizationofTrump’sforeignpolicywillhaveatremendousimpactontheUSitselfandonitsexternalenvironmentwitheffectstoberevealedastimegoesby.