简介：在女人的一生中，任何时期都可能遭受阴道炎的袭击。其危害可以说是多方面的，除了给生活、工作及学习带来诸多不便外，炎症本身还有可能蔓延至尿道、宫颈、子宫附件等邻近器官，引起感染；长期慢性炎症可造成不孕或流产；同时，还可通过性生活传播给伴侣，导致伴侣感染。姐妹们，还等什么？快快行动起来，让阴道炎走开!

简介：Runningisbelievedtobebeneficialforhumanhealth.Manystudieshavefocusedontheneuroprotectiveeffectsofvoluntaryrunningonanimalmodels.Therewerebothprimaryandsecondarydegenerationinneurodegenerativediseases,includingglaucoma.However,whetherrunningcandelayprimaryorsecondarydegenerationorbothofthemwasnotclear.Partialopticnervetransectionmodelisavaluableglaucomamodelforstudyingbothprimaryandsecondarydegenerationbecauseitcanseparateprimary(mainlyinthesuperiorretina)fromsecondary(mainlyintheinferiorretina)degeneration.Therefore,wecomparedthesurvivalofretinalganglioncellsbetweenSprague-Dawleyratrunnersandnon-runnersbothinthesuperiorandinferiorretinas.Excitotoxicity,oxidativestress,andapoptosisareinvolvedinthedegenerationofretinalganglioncellsinglaucoma.Sowealsousedwesternimmunoblottingtocomparetheexpressionofsomeproteinsinvolvedinapoptosis(phospho-c-JunN-terminalkinases,p-JNKs),oxidativestress(manganesesuperoxidedismutase,MnSOD)andexcitotoxicity(glutaminesynthetase)betweenrunnersandnon-runnersafterpartialopticnervetransection.Resultsshowedthatvoluntaryrunningdelayedthedeathofretinalganglioncellsvulnerabletoprimarydegenerationbutnotthosetosecondarydegeneration.Inaddition,voluntaryrunningdecreasedtheexpressionofglutaminesynthetase,butnottheexpressionofp-JNKsandMnSODinthesuperiorretinaafterpartialopticnervetransection.Theseresultsillustratedthatprimarydegenerationofretinalganglioncellsmightbemainlyrelatedwithexcitotoxicityratherthanoxidativestress;andthevoluntaryrunningcoulddown-regulateexcitotoxicitytodelaytheprimarydegenerationofretinalganglioncellsafterpartialopticnervetransection.