简介:目的:探讨微创结膜囊鼻腔吻合术治疗完全性上下泪小管阻塞的有效性,并评价这种手术的优势、术后并发症及患者满意度。方法:选取完全性上下泪小管阻塞患者22例22眼作为研究对象,施行微创结膜囊鼻腔吻合术。术后随访3~27mo,记录患者的人口学数据、手术时长、义管长度、随访时间、义管的通畅情况、术后并发症、对手术是否满意,分析数据结果,评价微创结膜囊鼻腔吻合术的临床意义。结果:手术总体成功率为95%(21/22),患者总体满意度为68%(15/22)。术后并发症包括鼻腔肉芽组织包裹义管下口2例(9%),中鼻甲黏膜堵塞义管下口3例(14%),鼻黏膜覆盖义管下口1例(5%),义管管腔被分泌物堵塞5例(23%),异物不适感10例(45%),干眼2例(9%),鼻腔分泌物逆流入结膜囊8例(36%)。结论:微创结膜囊鼻腔吻合术可有效治疗完全性上下泪小管阻塞。手术方法操作简单,成功率高,手术时间短,组织损伤小,并发症少,且不遗留面部皮肤瘢痕。
简介:目的:比较常规泪小管断裂吻合术和鼻内窥镜引导逆行注气法联合5-氟尿嘧啶治疗泪小管断裂的手术时效和疗效。方法:收集秦皇岛市海港医院眼科2009-01/2015-12下泪小管断裂行手术治疗的患者67例67眼的临床资料进行研究。采用数字表法随机将患者分为A组和B组。A组33例33眼行常规泪小管断裂吻合术,B组34例34眼行鼻内窥镜引导逆行注气法联合5-氟尿嘧啶治疗泪小管断裂。分别采用独立样本t检验和Mann-Whitney秩和检验的方法对两组的找到泪小管断端的时间和手术疗效进行比较。结果:A组找到泪小管断端的时间为44.42±10.66min,B组找到泪小管断端的时间为30.06±6.21min,两组比较,差异有统计学意义(t=6.72,P〈0.05)。术后6mo冲洗泪道判断手术疗效,B组疗效优于A组,差异有统计学意义(Z=2.47,P〈0.05)。结论:鼻内窥镜引导逆行注气法联合5-氟尿嘧啶治疗泪小管断裂和常规泪小管断裂吻合术相比,手术时间短,术后疗效佳。
简介:AIM:Toinvestigatethepossiblerelationshipbetweentheinfluencingfactorsoccurringbeforeandduringbirthinfull-terminfantsandtheoutcomeofretinopathy.·METHODS:Totally816full-terminfantsadmittedintheneonateintensiveunitofBoaiHospitalofZhongshanbetween1May,2008and30June,2011wereincludedinthestudy.Fundusexaminationwasperformedandevaluatedindividuallyonthemattheageof48hoursafterdelivery,2weeksand1month.Somepossibleriskfactorshappeningprenatallyorduringdeliverysuchaspregnantrelatedhypertension,placentaprevia,placentalabruptionetc,aswellassomeneonatalriskfactorssuchasneonatalasphyxia,hypoxic-ischemicencephalopathy(HIE),lowbirthweightetc,wererecordedandevacuated.Thentheeffectoftheriskfactorsoffull-terminfantsonretinopathywasstudied.·RESULTS:Theincidenceofretinalhemorrhageoffull-terminfantswithprenatalpregnantrelatedhypertension(PRH)ofthemother(43.6%)wassignificantlyhigherthanthatoffull-terminfantswithout(8.0%).(P<0.001).Theincidenceofretinalhemorrhageoffull-terminfantswithneonatalasphyxiaand/orhypoxic-ischemicencephalopathy(HIE)(29.3%)wassignificantlyhigherthanthatofthosewithout(15.7%),butcorrelationwasnotfoundbetweentheseverityofretinahemorrhageandthedegreeofhypoxicdisease.Apalecolorofopticdiscwasassociatedwithalowbirthweightoffull-terminfant.Full-terminfantswithbirthweighlessthan2500ghadasignificanthigherincidenceofretinopathythanthosewithbirthweightequalormorethan2500g(P<0.001).·CONCLUSION:Themaininfluencingfactorswhichleadtoretinopathyofhighriskfull-terminfantsareprenatalfactorssuchasPRH,andsomeneonatalriskfactorssuchasasphyxia,hypoxic-ischemicencephalopathy,andlowbirthweight.
简介:目的观察泪道探通后氟尿嘧啶应用联合鼻泪管中逆行植入球头硅胶管术治疗慢性泪囊炎的临床疗效。方法从门诊就诊的泪道阻塞患者中,选取泪点泪小管均通畅的慢性泪囊炎患者42例(56只眼),随机分为实验组与对照组,治疗组采用先泪道探通扩张,并将氟尿嘧啶溶液浸入阻塞创面,后经鼻腔逆行植入球头硅胶管术治疗,对手术疗效进行分析。对照组则不采用氟尿嘧啶干预措施,其余治疗与对照组相同。两组患者均于术后3个月拔管。结果拔管后随访3~12个月,治疗组21例(29只眼)中有效25只眼,泪道冲洗通畅无分泌物,2只眼冲洗欠通畅无分泌物,2眼泪道冲洗仍阻塞,治愈率86.2%。对照组21例(27只眼)中有效17只眼,泪道冲洗通畅无分泌物,4只眼冲洗欠通畅无分泌物,6眼泪道冲洗仍阻2塞,治愈率63.0%。经χ检验治疗组治愈率高于对照组(P〈0.05)。结论泪道探通联合球头硅胶管逆行植入术治疗慢性泪囊炎具有操作简便、不切皮肤、不损伤组织结构等优点,临床疗效肯定。氟尿嘧啶对于预防泪道阻塞部位创面再次粘连,提高远期疗效有确切作用。