简介:摘要随着社会的进步,经济的快速发展,人们在物质生活水平不断提高的同时,对于水乡片区河道无休止的索取也越来越多,从而使得河流域内优美的自然环境以及完整的生态系统遭到了严重的破坏,水资源污染程度也变得越来越严重,改善河道生态环境,修复和构建生态型河道已经引起人们的广泛关注,再加上,我国本身就是一个贫水国家,人均用水量就比较低,因此,我国一定要加大水乡片区河道治理的生态化建设力度,有效的水乡片区河道治理生态化建设不仅能够改善自然生态环境,实现人与自然和谐发展的目标,而且还能够提高人们的生活质量,推动社会经济的不断进步与发展。本文就从水乡片区河道治理中存在的问题出发,提出了有效治理河道,实现水乡片区河道治理现代化建设的具体措施。
简介:AbstractIntroduction:Neuroblastoma (NB) is the most common extracranial solid tumor among children. The 5-year event-free survival rate for high-risk (HR) NB is still poor, especially for patients with advanced NB with MYCN gene amplification. Chimeric antigen receptor T (CAR-T) cell therapy is a new treatment for HR-NB.Case presentation:A 55-month-old boy with stage IV HR-NB received 4th-generation CAR-T cells that target disialoganglioside GD2, as consolidation maintenance treatment after intensive chemotherapy, surgery, and autologous stem-cell transplantation. As of February 2019, his CAR-T follow-up time was 37.5 months, indicating prolonged survival. Cranial MRI and ultrasound showed no mass; 123I-metaiodobenzylguanidine (123I-MIBG) scan was negative.Conclusion:GD2-CAR-T cells may be an effective treatment option for NB patients with MYCN amplification.
简介:我区的农业起步较晚,秦汉时期,逐步有了一些种植业,明代时农业才开始有了一定的发展规模,直到清朝末年,种植业才有了较大规模的发展,逐步形成了目前的农业区和半农半牧区。我区的农业区和半农半牧区主要分布在大兴安岭和阴山山脉以东、以南地区。农作物主要种植区是河套、土默川、西辽河平原,嫩江沿岸平原和广大的丘陵区。这些地区有适于农作物生产的黑土、黑钙土、栗钙土、草旬土、淤灌土等多样性土壤地带和可利用的地上、地下水资源。我区的耕地面积自七十年代以来,一般保持在533万多公顷,共中水浇地面积约133万多公顷,占耕地面积的四分之一。四分之三是旱地农业,农作物为一季一熟。主要粮豆作物有小麦、玉米、水稻、谷子、莜