简介: 【摘要】 目的 进一步研究干扰素体外释放酶联免疫检验技术在结核病诊断中的优势, 为未来进一步提高结核病检出率奠定基础。方法 138 例患者, 分别接受结核菌素皮肤过敏试验与干扰素体外释放酶联免疫检验。比较两种检查方法诊断结核病的灵敏度、特异度 ; 不同结核病患者干扰素体外释放酶联免疫检验诊断准确率。结果 138 例患者, 病理确诊结核病 42 例, 非结核病 96 例。干扰素体外释放酶联免疫检验诊断结核病的灵敏度为 85.71% ( 36/42 )、特异度为 90.63% ( 87/96 ), 均高于结核菌素皮肤过敏试验的 66.67% ( 28/42 )、 80.21% ( 77/96 ), 差异具有统计学意义( P<0.05 )。肺结核患者 27 例, 肺外结核患者 15 例。肺外结核患者干扰素体外释放酶联免疫检验诊断准确率为 100.00% , 高于肺结核患者的 77.78% , 差异具有统计学意义( P<0.05 )。结论 干扰素体外释放酶联免疫检验方法满足结核病临床诊断的需求, 该诊断方法具有更高的阳性检出率, 并且还具有操作步骤简单、结果精准等优点, 能够减少误诊、漏诊等情况发生, 为结核病的早期预防、早期治疗奠定基础, 因此值得在临床上做进一步推广。 【关键词】 干扰素体外释放酶联免疫检验技术 ; 结核病 ; 结核菌素皮肤过敏试验 [Abstract] objective to further study the advantages of in vitro release of interferon enzyme-linked immunosorbent assay (ELISA) in the diagnosis of tuberculosis and lay a foundation for further improving the detection rate of tuberculosis in the future. Methods 138 patients were tested by tuberculin skin allergy test and interferon releasing enzyme-linked immunosorbent assay. The sensitivity and specificity of the two methods were compared, and the diagnostic accuracy of ELISA for ifn-ifn-release in vitro in different tuberculosis patients was compared. Results of the 138 patients, 42 were confirmed by pathology and 96 were non tuberculosis. The sensitivity and specificity of ELISA were 85.71% (36 / 42) and 90.63% (87 / 96) respectively, which were higher than 66.67% (28 / 42) and 80.21% (77 / 96) of tuberculin skin allergy test. There were 27 cases of tuberculosis and 15 cases of extrapulmonary tuberculosis. The diagnostic accuracy of ELISA was 100.00%, higher than that of 77.78% (P < 0.05). Conclusion the ELISA method of interferon releasing in vitro can meet the needs of clinical diagnosis of tuberculosis. This method has higher positive detection rate, simple operation steps and accurate results, which can reduce misdiagnosis and missed diagnosis and lay a foundation for early prevention and treatment of tuberculosis, Therefore, it is worthy of further promotion in clinical practice.
简介:摘要:目的:分析对肺内小结节良恶性鉴别应用CT三维成像技术的临床应用价值。方法:选取2021年12月—2022年12月医院收治的经手术病理明确诊断为肺内小结节良恶性鉴别的患者98例,以患者入院先后顺序将其分为对照组和研究组,每组49例,对照组采取常规CT诊断,研究组采取CT三维成像技术技术诊断,比较两组影像优良率、检查所耗时间、诊断符合率、误诊及漏诊率并对诊断技术的临床应用价值进行浅析。结果:研究组图像优良率97.96%显著高于对照组的83.67%(P<0.05);研究组检查所耗时间显著短于对照组(P<0.05);两组术后病理诊断结果显示,研究组诊断符合率高于对照组,误诊及漏诊率低于对照组,差异均有统计学意义(P<0.05)。结论:CT三维成像技术在肺内小结节良恶性鉴别中的应用价值显著,诊断准确率高,适合在临床实施和开展。
简介:摘要:目的:分析头颈部肿瘤调强放疗摆位误差中应用图像引导放射治疗技术不同验证模式的效果。方法:采集对象:头颈部肿瘤患者,均配合IGRT技术,研究资料采集50例,资料采集起始时间2022年05月,结束时间2023年10月,应用1:1随机数字法,对照组25例,配合EPID位置验证,实验组25例,配合三维锥体束CT位置验证。分析不同验证模式对调强放疗摆位误差的影响。结果:两种验证模式的摆位误差较小P>0.05;比较对照组,实验组验证效果统计数值更高,P<0.05。讨论:对头颈部肿瘤调强放疗摆位误差验证中,图像引导放射治疗技术的两种验证模式的摆位误差并不明显,验证效果各有优势。
简介: [摘要 ] 目的 探讨分析彩超用于早期诊断糖尿病患者下肢血管病变的临床价值。方法 随机选取 2018年 12月— 2019年 12月期间该院收治的糖尿病患者 45例和非糖尿病患者 45例作为研究对象,将 45例糖尿病患者分为观察组, 45例非糖尿病患者分为对照组,对所有研究对象进行彩色多普勒超声检查,观察比较两组的检查结果。结果 观察组患者中有 34例( 75.56%)出现动脉粥样硬化,有 35例( 77.78%)出现动脉斑块,有 33例( 73.33%)患者出现管腔狭窄或者闭塞;对照组患者中有 4例( 8.89%)出现动脉粥样硬化,有 12例( 26.67%)出现动脉斑块,有 8例( 17.78%)患者出现管腔狭窄或者闭塞,观察组患者的动脉粥样硬化、动脉斑块以及管腔狭窄或者闭塞发生率明显高于对照组;观察组患者的血管动脉血流速为( 35.12±3.27) cm/s、血流量为( 27.84±9.18) mL/min;对照组患者的血管动脉血流速为( 44.58±3.93) cm/s、血流量为( 45.67±10.34) mL/min,观察组患者的血管动脉血流速与血流量明显低于对照组,差异有统计学意义( P<0.05)。结论 综上所述,彩超在糖尿病患者下肢血管病变的早期诊断中临床价值较高,检出率高,值得推广。 [关键词 ] 彩超:早期诊断糖尿病;下肢血管病变;临床价值 [Abstract] Objective To explore the clinical value of color Doppler ultrasound in the early diagnosis of diabetic patients with lower extremity vascular disease. Methods 45 cases of diabetic patients and 45 cases of non-diabetic patients in our hospital from December 2018 to December 2019 were randomly selected as the research objects. 45 cases of diabetic patients were divided into the observation group and 45 cases of non-diabetic patients were divided into the control group. All the subjects were examined by color Doppler ultrasound, and the examination results of the two groups were observed and compared. result In the observation group, 34 cases (75.56%) had atherosclerosis, 35 cases (77.78%) had arterial plaque, 33 cases (73.33%) had lumen stenosis or occlusion; in the control group, 4 cases (8.89%) had atherosclerosis, 12 cases (26.67%) had arterial plaque, 8 cases (17.78%) had lumen stenosis or occlusion The incidence of atherosclerosis, atherosclerotic plaque and lumen stenosis or occlusion in the observation group was significantly higher than that in the control group; the blood flow rate and blood flow of the observation group were (35.12 ± 3.27) cm / s and (27.84 ± 9.18) ml / min; the blood flow rate and blood flow of the control group were (44.58 ± 3.93) cm / s and (45.67 ± 10.34) ml / min, respectively The flow rate was significantly lower than that of the control group (P < 0.05). Conclusion to sum up, color Doppler ultrasound in the early diagnosis of diabetic patients with lower extremity vascular disease has high clinical value and detection rate, which is worthy of promotion.
简介:【摘要】目的 对比微创经皮钢板接骨技术(MIPPO)+锁定加压钢板(LCP)与闭合复位静态交锁髓内钉在胫骨远端骨折治疗效果。方法 随机选取本院68例胫骨远端骨折患者,选取时间2019年3月-2020年6月,基于平行对照法分为甲组(34例,闭合复位静态交锁髓内钉治疗)与观察组(34例,MIPPO联合LCP治疗),比较治疗效果。结果 手术时间和术中出血量方面,甲组手术时间比乙组少,而术中出血量比乙组多,差异明显(P0.05)。结论 胫骨远端骨折治疗过程中,微创经皮钢板接骨术联合锁定加压钢板治疗与闭合复位静态交锁髓内钉治疗均具有显著治疗效果,但是每种治疗方法有着各自的优点和不足,所以需要根据病情变化对治疗方法进行选择。