简介：AbstractIntroduction:Trichofolliculoma characterized clinically by the presence of acentral dilated pore with tufted hairs and corresponds histologically to a central primary follicle and many secondary vellus hair follicles originating from it. Thus far, dermoscopy description of trichofolliculoma has been lacking.Here, we describe a typical case of trichofolliculoma, particularly the special manifestation under the dermoscopy.Case presentation:A 29-year-old man complained a five-year history of a nodule containing a central whitish hair plug on his left tempus. Dermoscopic examination revealed a well-defined, yellow macule with a central whitish hair plug surrounded by dilated capillaries, and histopathological analysis was consistent with trichofolliculoma.Discussion:The findings of dermoscopy were also vary, which may be affected by the origin of the disease, various phases of the hair cycle, depth of the lesion, and even external stimulus.Conclusion:Diagnosis of trichofolliculoma is sometimes difficult because the presence of the central crater and visible hairs is low, and dermoscopy examination may be a potentially useful diagnostic tool.