简介：针刺膝关节周围的4个穴位,犊鼻、内膝眼、梁丘和血海,得气后接电针,并用TDP照射膝关节,治疗了78例膝关节骨性关节炎患者.治疗2个疗程后,临床治愈26例,显效18例,好转31例,无效3例,总有效率96.2%.

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简介：由使随机化的控制试用为膝骨关节炎(洋槐的一种)观察温暖的刺破的艾灸的临床的效果。

简介：ArthritisistheleadingcauseofdisabilityinolderadultsintheUnitedStates.1Osteoarthritis(OA)isthemostcommonformofarthritis,andkneeandhipthemostaffectedjoints.SomeofthecommonriskfactorsareassociatedwithkneeandhipOAincludingage,bodyweight,pastjointinjuries,andsportparticipation.Participationinstrenuoussportsincreasestherisksofinjuries.However,itisnotclearifparticipationindifferentsportspresentsdifferentrisksforOA.2Forexample,itiswellknownthatrunningincreasestheriskforkneeinjuries,butitremainsunknownifrunningisassociatedwithan

简介：Objective:Tocomparethetherapeuticeffectofpointpenetrationmethodoflongneedleandthatofwesterndruginthetreatmentofkneeosteoarthritis.Methods:Thesimpleandrandomizedgroupingmethodwasusedinpresentstudy.Results:Theeffectiverateintheacupuncturegroupwas87.5%,andinthewesterndruggroupwas55.6%,thesignificantdifferencewasfoundbetweentwogroupsinthetherapeuticeffect(P＜0.01).Conclusions:Thetherapeuticeffectofpointthroughpointwithlongneedleinthetreatmentofkneeosteoarthritiswasbetterthanthatofwesterndrug.

简介：Background:NostudieshavecomparedeffectivenessofresistancetrainingandTaiJiexerciseonrelievingsymptomsofkneeosteoarthritis(OA).Thepurposeofthestudywastoevaluateeffectsofa10-weekTaiJiandresistancetraininginterventiononimprovingOAsymptomsandmobilityinseniorswithkneeOA.Methods:Thirty-oneseniors(60-85years)wererandomlyassignedtoaTaiJiprogram(n=12),aresistancetrainingprogram(n=13),andacontrolgroup(n=6).AllparticipantscompletedtheWesternOntarioandMcMaster(WOMAC)OsteoarthritisIndexandperformedthreephysicalperformancetests(6-minwalk,timed-up-and-go,andtimedstairclimbanddescent)beforeandafterthe10-weekintervention.Results:Theparticipantsintheresistancetraininggroupsignificantlyimprovedonthetimed-up-and-gotest(p<0.001),theWOMACpainsubscore(p=0.006),WOMACstiffnesssub-score(p<0.001),andWOMACphysicalfunctionsub-score(p=0.011).TheTaiJigroupsignificantlyimprovedonthetimed-up-and-gotest(p<0.001),butnotontheWOMACscores.Conclusion:ResistancetrainingwaseffectiveforimprovingmobilityandimprovingthesymptomsofkneeOA.TaiJiwasalsoeffectiveforimprovingmobility,butdidnotimprovekneeOAsymptoms.

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简介：Kneeosteoarthritisisacommonlyencountereddiseasemostlyseeninthemiddleaged,elderlyandphysicallabors,affectingweight-bearingkneejoints.Theauthorhastreated86casesofosteoarthritiswithacombineduseofcollateralpuncturing-cuppingandacupuncture.Itisnowreportedasfollows.

简介：Objective:Toevaluatetheoutcomeoftotalhiparthroplasty(THA)withcementlesscupsandfemoralheadautograftsforpatientswithhipdysplasiaandosteoarthritis.Methods:Between1995and2002,weimplanted23cementlesscupsandfemoralheadautograftsin20patientswithhipdysplasiaandosteoarthritis.Inthisstudy,aretrospectivestudywasmadeon21hipsin20patients(18femalesand2males,aged50yearsonanaverage)withdevelopmentalhipdysplasiatreatedbyTHAwithacementlesscupandfemoralheadautograft.Theacetabularcupwasplacedatthelevelofthetrueacetabuinmandallthepatientsrequiredautogenousfemoralheadgraftsduetoacetabulardeficiency.Theaveragerateoftheacetabularcupcoveredbythefemoralheadautograftwas31%(rangingfrom10%to45%).Eighthipshadlessthan25%cupcoverageandthirteenbetween25%and50%.Theaveragefollow-upperiodwas4.7years(range,1-8years).ThereplacingoutcomewasevaluatedbymodifiedHarrishipscore.Preoperativeandfollow-upradiographsweremade.Results:Alltheautograftswereunitedtothehostbones.Noautograftwascollapsedornocomponentfromthehipwasloosedinallthepatients.AccordingtothemodifiedHarrishipscore,theaveragehipscoreincreasedfrom46beforeoperationto89atthefinalreview.Beforeoperation,theleg-lengthdiscrepancywasgreaterthan2cminallthepatientsexceptonewithbilateralhipdysplasia.Afteroperation,only2outof20patientshadaleg-lengthdiscrepancygreaterthan1cm.Threehipsshowedminorboneresorptioninthelateralportionofthegraft,whichdidnotsupportthecup.ThreehipsdevelopedGrade1BrookerheterotopicossificationandonedevelopedGrade2.Conclusions:THAwithacementlesscupandafemoralheadautograftforpatientswithosteoarthritisresultedfromhipdysplasiacanresultinfavorableoutcomes.Thismethodcanprovidereliableacetabularfixationandrestoretheacetabularbonestockinpatientswithdevelopmentalhipdysplasiawhenthe

简介：Osteoarthritisofthekneejointisoneoftheosteoarthropathyandisoftenseeninmid-agedandoldpeopleinclinic.Uptonow,therehasbeennoanyeffectivemedicationtotreatit.Theauthoremployedacupuncturewiththeneedlewarmedbyburningmoxaandachievedsatisfactoryresults.Hereisthereport.

简介：AbstractPurpose:The treatment and outcome of tibial stress fractures concomitant with knee osteoarthritis (OA) are complicated. The aim of this study was to evaluate the functional and radiological outcome of total knee arthroplasty with long tibial stem as a treatment for patients having knee OA and tibial stress fracture.Methods:Patients who were diagnosed to have proximal tibia stress fracture along with knee OA at our institution between June 2013 and November 2018 were included in our study. All patients underwent total knee arthroplasty with long tibial stem. Preoperative and postoperative functional assessments were done according to range of movement of the knee joint, knee society score and knee injury and OA outcome score. Descriptive analysis was carried out by mean and standard deviation for quantitative variables, frequency and proportion for categorical variables.Results:Twelve patients were included in the study. All patients were found to have stress fractures in the proximal half of tibia and extra-arthrosis. Four patients had non-union/delayed union, and 8 patients had acute fractures. The average preoperative range of movement was 88.1°, which improved to 116.3° at 3 months following surgery. It was found that the fracture has healed in all cases. Mean knee society score improved from 32.9 preoperatively to 89.3 at 1 year follow-up. Knee injury and OA outcome score improved from a mean score of 28.3 preoperatively to 81.1 at 1 year follow-up.Conclusion:Stress fractures can occur in the proximal tibia in patients with knee OA. Total knee arthroplasty with tibial stem provides a suitable solution for both conditions. Additional plating or bone graft is unlikely to be required.

简介：Background:AlthoughTaiJiQuanhasbeenshowntorelievepainandimprovefunctionalmobilityinpeoplewithkneeosteoarthritis(OA),littleisknownaboutitspotentialbenefitsongaitcharacteristicsamongolderChinesewomenwhohaveahighprevalenceofbothradiographicandsymptomatickneeOA.ThisstudyaimstoassesstheefficacyofatailoredTaiJiQuaninterventionongaitkinematicsforolderChinesewomenwithkneeOA.Methods:Arandomizedcontrolledtrialinvolving46olderwomeninShanghai,China,withclinicallydiagnosedkneeOA.Randomized(1:1)participantsreceivedeithera60minTaiJiQuansession(n=23)3timesweeklyora60minbi-weeklyeducationalsession(n=23)for24weeks.Primaryoutcomeswerechangesingaitkinematicmeasuresfrombaselineto24weeks.SecondaryoutcomesincludedchangesinscoresontheWesternOntarioandMcMasterUniversityOsteoarthritisIndex(WOMAC)andShortPhysicalPerformanceBattery(SPPB).Results:After24weekstheTaiJiQuangroupdemonstratedbetterperformanceingaitvelocity(meandifference,8.40cm/s,p=0.01),steplength(meandifference,3.52cm,p=0.004),initialcontactangle(meandifference,2.19°,p=0.01),andmaximalangle(meandifference,2.61°,p=0.003)offlexedkneesduringstancephasecomparedtothecontrolgroup.Inaddition,theTaiJiQuangroupshowedsignificantimprovementinWOMACscores(p<0.01)(meandifference,-4.22pointsinpain,p=0.002;-2.41pointsinstiffness,p<0.001;-11.04pointsinphysicalfunction,p=0.006)andSPPBscores(meandifference,1.22points,p<0.001).Conclusion:AmongolderChinesewomenwithkneeOA,atailoredTaiJiQuaninterventionimprovedgaitoutcomes.TheinterventionalsoimprovedoverallfunctionasindexedbytheWOMACandSPPB.TheseresultssupporttheuseofTaiJiQuanforolderChineseadultswithkneeOAtobothimprovetheirfunctionalmobilityandreducepainsymptomatology.

简介：Osteoarthritis(OA)isthemostcommonformofarthritis.ThekneeandhipjointsarethemostcommonsitesforOA,andkneeOAismoreprevalentthanhipOA.1KneeOApatientsoftensufferpain,functionaldisability,articularcartilagewearandrelatedjointspacenarrowing.AmongU.S.adults,46.4millionhavephysician-diagnosedarthritisrepresenting

简介：摘要目的探讨和分析氨基葡萄糖对膝骨关节炎(osteoarthritis,DOA)的治疗方法在临床中应用中的疗效体会，为广大骨关节炎病患者的治疗提供参考。方法选取本院2010年10月-2012年10月期间采用盐酸氨基葡萄糖治疗90例膝DOA患者。男性患者36例、女性患者54例；年龄均在45岁～75岁，平均年龄60.5岁，病程2个月到6年不等。口服盐酸氨基葡萄糖片、每日三次、每次480毫克，6周为一疗程，4～6个月重复一个疗程。所有患者均经过2个疗程的治疗后，（采用国际DOA的评分标准Leuesne指数评定膝关节休息疼痛、运动疼痛、压痛、关节活动度、晨僵和活动能力）。结果有85例患者膝关节疼痛、活动度、晨僵均有不同程度的好转，有10例患者在第一疗程后膝关节疼痛消失，有20例患者在第一疗程结束后疼痛、晨僵明显缓减、膝关节活动度明显改善，有15例患者在第二疗程结束后疼痛消失，有52例患者在第二疗程治疗结束后、膝关节疼痛、晨僵等女明显好转、活动度明显改善，有5例患者无效，有3例患者出现胃部不适（既往患者有慢性胃炎史，患者自服奥美拉唑缓减）。结论盐酸氨基葡糖治疗退行性骨性关节炎，可延缓骨关节炎的病理过程，延缓病情的进展、缓减疼痛、肿胀等症状，改善关节功能，延缓关节变性形成，适合在临床上进行推广与应用。

简介：AbstractBackground:Osteoarthritis (ΟΑ) is characterized by cartilage breakdown and subchondral sclerosis. Micro-fractures of the calcified tissues have been, also, detected, but their exact role has not been elucidated yet. This study was to examine the frequency of cracks during OA progression and to correlate them with the underlying cellular modifications and matrix metalloproteinase-2 (MMP-2) expression using histological/immunohistological methods.Methods:Overall, 20 patients and 3 controls (9 specimens per patient), aged 60-89 years, diagnosed with hip/knee OA were included. The development of cracks was examined in 138 sections, whereas the expression of MMP-2 was examined in 69 additional sections.Results:Based on Mankin score, three groups of OA severity were analyzed: Group I (mild) was constituted of sections with score 1-5 while Groups II (moderate) and III (severe) with score 6-7 and greater or equal to 8, respectively. Demographic characteristics did not reveal any association between the number of microdefects and age or body mass index (BMI). Cartilage micro-cracks were increased during moderate and severe OA, while bone cracks were increased during mild and severe OA. In knee OA, cartilage cracks were not correlated with Mankin score, whereas in hip OA they appeared association with severity score. Bone cracks were positively correlated with matrix apoptotic osteocytes and osteoblastic cells, but not with osteoclasts. MMP-2 immunostaining was increasing by OA severity in the osteochondral unit. Similarly, MMP-2 was expressed on the microcracks’ wall mainly in Group III.Conclusion:Our data displayed that bone cracks during primary OA stages, represent an early adaptative mechanism aiming to maintain cartilage integrity. Accumulation of bone defects and concomitant increase of apoptotic osteocytes activated an abnormal remodeling due to osteoblastic activity, in which MMP-2 played a pivotal role, leading to subchondral sclerosis promoting further osteochondral deformities.

简介：Objective:Toobservetheinfluenceofintra-articularinjectionofsodiumhyaluronate(HA)onthemRNAexpressionsofmatrixmetalloproteinase-1,-3(MMP-1,-3)andtissueinhibitorofmetalloproteinase-1(TIMP-1)incartilageandsynoviumoftraumaticosteoarthritis(OA).Methods:Sixteenwhiterabbitsunderwentunilateralanteriorcruciateligamenttransection(ACLT)weredividedinto2groupsrandomly5weeksaftertransection.Theexperimentalgrouprabbitsreceived0.3mlof1%HAbyintra-articularinjectiononceaweek.Animalsinthecontrolgroupweretreatedunderthesameconditionsusingphysiologicalsaline.Tenweeksfollowingsurgery,cartilageandsynoviumwereharvested.ThemRNAexpressionsofMMP-1,MMP-3andTIMP-1wereanalyzedusingreversetranscription-polymerasechainreaction(RT-PCR).Results:Insynovium,themRNAexpressionofMMP-3wassuppressedintheHAinjectiongroup.HAtreatmenthadnoeffectontheMMP-3expressionincartilage.NosignificantdifferenceofMMP-1andTIMP-1expressionsincartilageandsynoviumwasfoundbetweentheHAinjectiongroupandthecontrolgroup.Conclusions:OneofthemechanismsofthetherapeuticeffectofHAmaybetheinhibitionofexpressionofMMP-3insynoviumduringearlystageoftraumaticOA.