简介：ASpecializedCommitteeofREInforma-tionundertheChineseRESocietyhasbeenformedwiththepurposeofstreng-theningtheexchangeofREinformationandpromotingthedevelopmentofREsci-enceandtechnologyathomeandabroad.ThefirstmeetingofthecommitteewasheldinBeijingonDecember23-25,1989,andwasattendedbyover100representa-tivesfromuniversitiesandscientificresearchinstitutionsinvariouspartsofChina.Amongthemweresomewell-knownscholarswhohavelongbeenengagedin

简介：In1946,WorldWarⅡhadjustrecentlyended.Moreandmorepeoplewerefloodingtosportingevents,especiallycollegebasketball.MaxKase,asportseditoroftheNewYorktoldtheowneroftheNationalHockeyLeague,WalterBrown,abouthisidea,andBrowntookthei-deatoNedIrish.Nedstatedhewasalreadyworkingonsuchaleague,andKasedideventuallyreceiveseveralthousanddollarsforhisefforts.

简介：Thedemographicstructureofpopulations,particularlyageandsex,hasprofoundconsequencesforharmoniousandsustainablesocialandeconomicdevelopment.Furthermore,analyzingsexratiosofpopulationsisimportantinanalyzingthedevelopmentofthestatusOfwomenandgirls.

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简介：教学目标1.学生能够在谈论生肖的活动中巩固、复习本单元词汇和短语,并正确运用;2.学生能够在谈论生肖这一语境中运用功能句型表达十二生肖的轮回、顺序及生肖特征;3.学生能够在推算年龄、制作海报等活动中,利用单元所学语言表达和交流十二生肖传统文化,体会中国传统文化的智慧。教学重点与难点(一)重点1.熟练掌握十二生肖的名称,轮回频率,顺序及生肖特征;

简介：Sincethe1980s,especiallythemid-1980s,theimbalanceinthesexratioatbirthinChinahasbeenincreasingcontinuouslyandthesituationhasworsenedinrecentyears,accordingtothefourthandfifthcensusesin1990and2000.Thisissuehasdrawnwidespreadattentionfromthegovernmentaswellasacademia.Thefundamentalreasonfortheimbalance

简介：WeconsideroptimalbirthcontrolfortheMcKendrickequationofpopulationdyna-mics.Itconsistsofoptimizingasystemdescribedbyafirstorderpartialdifferentialequationwithnonlo-calbilinearboundarycontrol.ApproximateminimumprinciplesareobtainedusingEkeland’svariationalprinciple.

简介：AbstractPreterm parturition is the consequence of pathological signals that activate the common pathway of parturition and considered as a syndrome. Many risk factors for spontaneous preterm birth (sPTB) have been identified. Two significant risk factors for sPTB are history of prior sPTB and short cervical length at midtrimester. 17 hydroxyprogesterone caproate, vaginal progesterone, cerclage, and pessary have all been studied for prevention of sPTB. Difference in patient populations likely contributes to the conflicting study results. Further studies are needed to establish strategies in prevention of sPTB in singleton as well as multiple pregnancies.

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简介：AbstractThe time of birth is a critical determinant of perinatal and long-term outcomes, and even trans-generational effects. Preterm birth is still the leading cause of infant mortality and morbidity. Unfortunately, rates of preterm birth remain high worldwide. Preterm parturition is a complex syndrome, which can be induced by several factors such as infection, cervical pathology, uterine overdistension, progesterone deficiency, vascular alterations (utero-placental ischemia, decidual hemorrhage), maternal and fetal stress, allograft reaction, allergic phenomena, and probably other several unknown factors. The mechanisms responsible for early labor activation have been partially identified and involve receptors, chemokines, and inflammatory cytokines. It is very useful to understand the cellular and biochemical pathways responsible for preterm labor activation to identify, treat, and prevent negative outcome in a timely manner. Researchers and clinicians play a key role in improving biochemical knowledge on preterm delivery, identifying risk factors, and applying multilevel preventive strategies.

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简介：Birthdefectsaffectthequalityofthenewbornpopulation,andhavebecameamajorpublichealthprobleminChina.Geneticfactors,environmentalfactors,andtheinteractionofthetwoisthedirectcauseoftheincidenceofbirthdefects.Thisreview,basedontheneuraltubedefectsasanexample,giveinsightintothepathogenesisofbirthdefectsfromthegenomics,epigenetics,metabonomicsandenvironmentfactorsandexplorenewstrategyofbirthdefectpreventioninChina.

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简介：AbstractObjective:To investigate the roles of transcription factors (TFs) in the etiology of complex human birth defects, including neural tube defects (NTDs), congenital heart diseases (CHDs), and hypospadias.Methods:We examined the overlap of genetically associated genes among NTDs, CHDs, and hypospadias. We then compared the expression profiles of these diseases based on all the detected genes and disease-associated TFs. The differentially expressed TFs that we obtained were further subjected to functional enrichment analysis to elucidate their role in the development of these birth defects.Results:TF genes were significantly enriched in complex birth defects (P= 5.95 × 10-24). NTDs, CHDs, and hypospadias showed distinct gene expression profiles compared with the controls. Although TFs could not efficiently separate CHDs from normal subjects, distinct gene expression profiles of TFs could distinguish NTDs and hypospadias from controls. Differentially expressed TFs can be used to characterize NTDs, hypospadias, and controls. The enriched TFs in biological processes (BPs) reflected the different morphological processes of NTDs, CHDs, and hypospadias.Conclusions:This study indicates that abnormal expression patterns of specific TFs may disrupt the normal requirements for developmental equilibrium through the related BPs. The investigation of genetically associated genes and gene expression profiles for the three different complex birth defects provides new insights into how the dysregulation of TFs influences their developmental process.

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简介：TofurtherimplementthespiritoftheThirdPlenarySessionoftheEighteenthPartyCentralCommittee,conscientiouslysumupcomprehensivemanagementofsexratioatbirthin2013andfullyarrangethetasksin2014,onDecember20,2013,NationalMeetingonComprehensiveManagementofSexRatioatBirthwasheldinFuzhou

简介：ChenYifan,whoisresolvedtobesingleforlife,hasneverexpectedthatat45,shecanrealizeherdreamofproducingababyforherselfwithouthavingtogetmarried—andlegally.ThewomanisquitesuccessfulinhercareerasmanagerofaprivatecompanyinChangchunCity,JilinProvince,northeastChina.Herpersonallife,however,isnot.Shefellinlovewithaclassmatebackintheearly1980s,andwasheart-brokenwhentheyoungmanlefther.Sincethen,thewomanhasfoundthatnomaninthisworldisgoodenoughtobeherhusband.Thoughsingle,shewantstohaveachildofherown.'I’llbeburningwithenvywheneverIseea