简介:Surgicaloptionsdevelopedtotreatcarotidarterystenosishaveevolvedinthelastsixdecades,andstudieshaveshownthesuperiorityofcarotidendarterectomy(CEA)comparedtomedicaltherapy.Similarly,asendovasculartherapyhasevolvedoverthelasttwodecades,studiesreflectingsafety,feasibility,andequivalenceofcarotidarterystenting(CAS)toCEAhavebeenreplicatedinseveralstudiesforintermediatetohighsurgicalriskpatients.However,sinceitsinception,thefieldofCAShasbeenmiredinseveralcontroversiesandhasbeensubjecttointensescrutinyfrommultiplestakeholderswithinthefieldofmedicine.ThisreviewdiscussesspecificissuesconcerningCASthatarerelevantinthecurrentera.
简介:ObjectivesToinvestigatesafetyandeffectivityofpotassiuminpreventionofrestenosisafterPTCA.MethodsEightypatientswithPTCAwererandomizedintotwogroups:Controlgroup(GroupⅡn=40)withconventionaltherapy;Treatmentgroup(GroupⅠn=40)withconventionaltherapyplusoralpotassium(Slow-K1.2g,q8h,given3daysbeforePTCAandcontinuedtotheendofsub-study).Observationindecesoftwogroupswerecomparedinfollow-up.ResultsSeventy-sevenpatientswerefollowed-up(39ingroupⅠ,38ingroupⅡ)Allbloodindices(includingfat,sugar,uricacid,cretonne,Na+,Cl-,Ca2+,Mg2+)exceptbloodpotassiuminbothgroupsweresimilar.Oralpotassiumcouldincreasebloodpotassiumlevelabout0.3mmol/LingroupⅠwithoutcausinganysideeffects.SuspiciousanginapectorisandevidenceofmyocardialischemiabyETTweredevelopedingroupⅡhad14patients(28.9%)andGroupIhad7patients(17.9%);6of17patients(35.3%)ingroupⅠand11of21patients
简介:OjbectiveTofindtheindependentpredictorsforrestenosisaftercoronarystenting.MethodsQuantitativeangiographywasperformedon60cases(67successfullydilatedlesions)afterangio-plastyover6-monthsfollow-up,andbothunivariateandmultivariatelogisticregressionanalysisweredonetoi-dentifythecorrelationsofrestenosiswithclinicalfactors.ResultsThetotalrestenosisratewas31.3%(21of67lesions),andaccordingtounivariateanalysisthepatientswhounderwentcoronarystenting≥3.5mmhadalowerrateofrestenosis(P<0.01).Collateralcirculationtotheobstructionsite,highmaximalinflationpressure,smokingandthelessminimallumendiameterafterPTCAmadetherateofrestenosishigherower(P<0.05).Multivariatelogisticregressionanalysisshowedthatcoronarystenting≥3.5mmhadalowrateofrestenosis,buthighmaximalinflationpressureandsmokingmadetherestenosisratehigher.ConclusionCoronarystentsize,maximalinflationpressureand.smokin
简介:Theoptimaldurationofdualantiplatelettherapy(DAPT)ofaspirinandaP2Y12receptorblockerafterstentingisstillbeingdebated.ThecurrentrecommendationsforDAPTdurationaresignificantlyfocusedonreducingstentthrombosis;alessfrequenteventwithlaterthanearliergenerationdrugelutingstents(DES).ApersistentoccurrenceoflateandverylatestentthrombosiswithfirstgenerationDESsupportedextendeduseofDAPTbeyondoneyear.However,recentstudieshavedemonstratedthatextendeddurationDAPTisassociatedwithincreasedbleeding;anindependentpredictorforpooroutcomes,includinglong-termmortality.Second-generationDESareassociatedwithlesslateandverylatestentthrombosis.SomerecentstudieshavesupportedashorterdurationofDAPTforsecondgenerationDES.However,thesestudieswereinadequatelypoweredtoassesssignificantdifferencesinstentthrombosis.Furthermore,extendeddurationDAPThasbeenassociatedwithareducedriskofthromboticeventsinnon-culpritvesselsinadditiontostentthrombosisinpatientswithacutecoronarysyndromes(ACS).ThehigherriskofbleedingassociatedwithextendedDAPTtherapyprovidesastrongrationaleforpersonalizedDAPTbasedonpatientriskfactors(e.g.ACSvs.non-ACS),typeofstents,andcost-benefitanalyses.
简介:目的:探讨经皮冠状动脉内血管成形术口CA)术后冠脉再狭窄临床治疗效果。方法:已进行过至少一次PTCA,临床和冠脉造影有再狭窄证据的患者,设定第一观察终点为冠脉造影再狭窄(定义为狭窄率超过管腔内径的50%),第二观察终点为死亡。结果:所有PTCA术后血流均达到TIMI3级,残余狭窄在30%以下,无发生严重并发症。结论:使用药物涂层支架或改进的支架和改进的球囊配合药物治疗PTCA术后再狭窄可以大大降低再狭窄的发生率。
简介:Wepresentthreecasesofself-expandablemetallicstent(SEMS)placementusingaballoonenteroscope(BE)anditsovertube(OT)formalignantobstructionofsurgicallyreconstructedintestine.ABEiseffectivefortheinsertionofanendoscopeintothedeepbowel.However,SEMSplacementisimpossiblethroughtheworkingchannel,becausetheworkingchannelofBEistoosmallandtoolongforthestentdevice.Therefore,weusedatechniqueinwhichtheBEisinsertedasfarasthestenoticarea;thereafter,theBEisremoved,leavingonlytheOT,andthenthestentisplacedbyinsertingthestentdevicethroughtheOT.Inthepresentthreecases,amodificationofthistechniqueresultedinthesuccessfulplacementoftheSEMSforobstructionofsurgicallyreconstructedintestine,andtheprocedureswereperformedwithoutseriouscomplications.Weconsiderthatthepresentprocedureisextremelyeffectiveasapalliativetreatmentfordistalbowelstenosis,suchasinthesurgicallyreconstructedintestine.
简介:ObjectiveTofurtherimprovetherateofreperfusionofinfarctionrelatedarteryinAMI,removethestricture,rescueischemicmyocardium,protectcardiacfunctionandamelioratethelong-termprognosis.MethodAmong73patientswithA-MI,50underwentdirectPICA,15immediatePICA,8rescuePTCAand20braceswereimplanted.ResultTheproportionofrecanalizationis94.5%(69/73).Thegradeofbloodflow(TIMI)improvedtograde3in20patientswithbraceimplantation,while44tograde3and5tograde2among49patientswithsimplePTCA.Residualstenosisinvesselwas1.8±5.9(-10-10)%inpatientswithbraceimplantationversus15.4±11.(0-30)%withsimplePTCA.Theincidenceofreperfusivecardiacarrythmiawas18.1%(10/62).Therewasmainlyfrequentventricularprematurebeatandshortparoxysmalventriculartachycardia,ifleftanteriordecendingbranchwasreopened,whilebradycardiaandatrialventricularblockusuallyoccurredafterrightcoronaryreperfused.ConclusionEmergencyP
简介:BackgroundTheimpactofincompleterevascularization(IR)onadverseoutcomesafterpercutaneouscoronaryinterventionremainsinconclusive,andfewstudieshaveexaminedmortalityduringfollow-upslongerthan5years.TheobjectiveofthisstudyistotestthehypothesisthatIRisassociatedwithhigherriskoflong-term(8-year)mortalityafterstentingformultivesselcoronarydisease.MethodsandResultsAtotalof13016patientswithmultivesseldiseasewhohadundergonestentingpro-cedureswithbaremetalstentsin1999to2000wereidentifiedintheNewYorkState'sPercutaneousCoronaryInterventionReportingSystem.Alogisticregressionmodelwasfittopredicttheprobabilityofachievingcompleterevascularization(CR)inthesepatientsusingbaselineriskfactors;then,theCRpatientswerematchedtotheIRpatientswithsimilarlikelihoodsofachievingCR.Eachpatient'svitalstatuswasfollowedthrough2007usingtheNationalDeathIndex,andthedifferenceinlong-termmortalitybetweenIRandCRwascompared.ItwasfoundthatCRwasachievedin29.2%(3803)ofthepatients.Forthe3803pair-matchedpatients,therespective8-yearsurvivalrateswere80.8%and78.5%forCRandIR(P=0.04),respectively.TheriskofdeathwasmarginallysignificantlyhigherforIR(hazardratio=1.12;95%confidenceinterval,1.01-1.26,P=0.04).The95%bootstrapconfidenceintervalforthehazardratiowas0.98to1.32.ConclusionsIRmaybeassociatedwithhigherriskoflong-termmortalityafterstentingwithBMSinpatientswithmultivesseldisease.Moreprospectivestudiesareneededtofurthertestthisassociation.
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简介:AbstractIntroduction:Early intervention in patients with congenitally disconnected pulmonary artery improves long-term outcome.Case presentation:We present 3 cases of isolated disconnected pulmonary artery in the absence of associated structural heart disease during a period of 3 years.Conclusion:Transcatheter stenting of the feeding ductus arteriosus re-established pulmonary artery flow and growth. Successful surgical repair was achieved, and normal perfusion and complete function of the ipsilateral lung were regained.
简介:AbstractIntroduction:Obstructed total anomalous pulmonary venous connection (TAPVC) is one of the commonest seen emergencies in pediatric cardiology centers.Case presentation:Our case was diagnosed to have this anomaly, showing early respiratory distress resulting from severe pulmonary congestion. Palliative stenting of the obstruction was done, which helped in stabilizing the debilitated hemodynamics of the baby before surgery, thus a good surgical outcome and prognosis are expected.Conclusion:This intervention may be listed as a vital measurement in the preoperative cardiac stabilization plan for infants with obstructed TAPVC.