简介:基于对域外P2P行业监管的梳理和分析,结合我国P2P小额信贷中介服务机构所兼具的创新性金融服务机构、投资咨询类中介服务机构和电子商务金融创新服务平台的三重性质,我国应当尽快完善并不断发展P2P小额信贷中介服务行业的法律制度体系建设,践行多方推动、统筹兼顾、虚实结合、着力创新、注重实效、规范发展、保障安全的新型监管理念并将政府主导型监管制度和市场需求引致型监管制度演变相结合,从而建立起由中国人民银行主导监管、银监会在相应业务领域紧密配合、地方政府严格实施、工商行政管理机关和工信部门积极参与的P2P行业监管框架.
简介:LowcarbonsteelswithBandPadditionswereremeltedbyelectromagneticlevitationandsolidifiedinavacuumdroptube.Thedropletvolumesweresettobe2mm×2mm×2mm(TM)and5mm×5mm×5mm(FM),respectively.Themicrostructureofrapidlysolidifiedsteeldroplets(cooledinsiliconoil)withPandbothBandPadditionwasobserved.ThemicrostructuresofB-bearingdropletsamplesweremoreuniformthanthoseofB-freeones,forbothTMandFMsamples.Thedistributionof℃andPalongthediameterofeachsamplewasdetected.Thewell-distributionof℃andPwasdetectedinB-bearingdropletsamples.SoitcouldbededucedthatBwasalsowelldistributedinthesteels.ItwasBatomsthatpromotedthewell-distributionof℃andP,whichfurtherimprovedtheuniformityofmicrostructureundertheconditionofrapidsolidification.Themicro-hardnessofBbearingsampleswashigherthanthatofB-freesamples,andthehardeningmechanismwasdiscussedindetail.
简介:摘要目的探讨p16蛋白和p27蛋白在宫颈癌中的表达及其临床意义。方法采用免疫组化SP法检测60例宫颈癌组织,51例宫颈上皮内瘤样病变(CIN)组织和30例正常宫颈组织中p16蛋白和p27蛋白的表达,并分析它们与宫颈癌临床病理因素的关系。结果宫颈癌组织中p16的阳性表达率(96.72%)明显高于CIN组(43.13%)和正常宫颈组(26.6%),P<0.01;表达水平与间质浸润、组织病理分级、有无淋巴结转移有关(P<0.05);与临床分期、组织类型无关(P>0.05)。p27蛋白在宫颈癌组织中的阳性表达率(24.59%)明显低于CIN组(65.1%)和正常宫颈组(89.7%),P<0.01;其表达水平与组织病理分级、间质浸润、淋巴结转移有关(P<0.05)。结论p16蛋白过表达、p27蛋白低表达与宫颈癌的发生发展有关,联合检测p16与p27蛋白对于早期诊断宫颈癌以及判断其侵袭转移潜能及预后有一定参考价值。
简介:The2008Wenchuanearthquake,amajorintraplateearthquakewithMw7.9,occurredontheslowlydeformingLongmenshanfault.Tobetterunderstandthecausesofthisdevastatingearthquake,weneedknowledgeoftheregionalstressfieldandtheunderlyinggeodynamicprocesses.Here,wedeterminefocalmechanismsolutions(FMSs)ofthe2008Wenchuanearthquakesequence(WES)usingbothP-wavefirst-motionpolaritydataandSH/Pamplituderatio(AR)data.AsP-wavepolaritiesaremorereliableinformation,theyaregivenpriorityoverSH/PAR,thelatterofwhichareusedonlywhentheformerhaslooseconstraintontheFMSs.Wecollectdatafromthreecategories:(1)permanentstationsdeployedbytheChinaEarthquakeAdministration(CEA);(2)theWesternSichuanPassiveSeismicArray(WSPSA)deployedbyInstituteofGeology,CEA;(3)globalstationsfromIncorporatedResearchInstitutionsforSeismology.Finally,129eventswithmagnitudeoverMs4.0inthe2008WESareidentifiedtohavewell-constrainedFMSs.Amongthem,83arewellconstrainedbyP-wavepolaritiesonlyasshownbyCaietal.(EarthqSci24(1):115–125,2011),andtherestofwhicharenewlyconstrainedbyincorporatingSH/PAR.BasedonthespatialdistributionandFMSsoftheWES,wedrawfollowingconclusions:(1)theprinciplecompressionaldirectionsofmostFMSsoftheWESaresubhorizontal,generallyinagreementwiththeconclusiongivenbyCaietal.(2011)butwithafewmodificationsthatthecompressionaldirectionsareWNW–ESEaroundWenchuanandENE–WSWaroundQingchuan,respectively.ThesubhorizontalcompressionaldirectionalongtheLongmenshanfaultfromSWtoNEseemstohavealeftlateralrotation,whichagreeswellwithregionalstressfieldinvertedbyformerresearchers(e.g.,Xuetal.,ActaSeismolSin30(5),1987;ActaGeophysSin32(6),1989;Cuietal.,SeismolGeol27(2):234–242,2005);(2)theFMSsoftheeventsnotonlyreflectedtheregionalstressstateoftheLongmenshanregion,butalsowereobviouslycontrolledbythefaultstosomeextent,whichwaspointedou